Search Results - "Faraonio, R"
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A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts
Published in Cell death and differentiation (01-04-2012)“…Here we show that replicative senescence in normal human diploid IMR90 fibroblasts is accompanied by altered expression of a set of microRNAs (miRNAs)…”
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p53 regulates the mevalonate pathway in human glioblastoma multiforme
Published in Cell death & disease (01-10-2015)“…The mevalonate (MVA) pathway is an important metabolic pathway implicated in multiple aspects of tumorigenesis. In this study, we provided evidence that p53…”
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In vitro acquired cellular senescence and aging-specific phenotype can be distinguished on the basis of specific mRNA expression
Published in Cell death and differentiation (01-08-2002)“…CELL DEATH AND DIFFERENTIATION: (2002) 9, 862-864. doi:10.1038/sj.cdd.4401053…”
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YO-4 - Molecular mechanisms of HO-1 up-regulation in neuroblastoma cell response to oxidative stress
Published in Free radical biology & medicine (20-05-2018)“…Heme oxygenase 1 (HO-1) up-regulation drives cell adaptation to different stressors. Previous works from our lab have shown that HO-1 plays a crucial role in…”
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Molecular mechanisms of HO-1 up-regulation in neuroblastoma cell response to oxidative stress
Published in Free radical biology & medicine (01-05-2018)Get full text
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Redox control of signal transduction, gene expression and cellular senescence
Published in Neurochemical research (01-03-2004)“…Reactive oxygen species (ROS) act as subcellular messengers in such complex cellular processes as mitogenic signal transduction, gene expression, regulation of…”
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Detection of cellular retinol-binding protein messenger RNA in the somatic cells of the rat seminiferous tubules
Published in Biochemical and biophysical research communications (15-08-1988)“…A cDNA clone coding for Cellular Retinol-Binding Protein (CRBP) was used as a probe to study the expression of the gene in the somatic cells of the…”
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The β-Amyloid Precursor Protein Functions as a Cytosolic Anchoring Site That Prevents Fe65 Nuclear Translocation
Published in The Journal of biological chemistry (02-03-2001)“…In this study we addressed the question of the intracellular localization of Fe65, an adaptor protein interacting with the β-amyloid precursor protein (APP)…”
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Fe65, a ligand of the Alzheimer's beta-amyloid precursor protein, blocks cell cycle progression by down-regulating thymidylate synthase expression
Published in The Journal of biological chemistry (20-09-2002)“…The functions of the Alzheimer's beta-amyloid precursor protein (APP) and of its complex with the adaptor protein Fe65 are still unknown. We have demonstrated…”
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Fe65 and the protein network centered around the cytosolic domain of the Alzheimer's β-amyloid precursor protein
Published in FEBS Letters (28-08-1998)“…A distinctive tract of all the forms of Alzheimer's disease is the extracellular deposition of a 40–42/43 amino acid-long peptide derived from the so-called…”
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Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein
Published in Biochemical journal (15-02-1998)“…We previously demonstrated that Fe65 protein is one of the ligands of the cytoplasmic domain of beta-amyloid precursor protein (APP). Another ligand of this…”
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Interaction of the Phosphotyrosine Interaction/Phosphotyrosine Binding-related Domains of Fe65 with Wild-type and Mutant Alzheimer's β-Amyloid Precursor Proteins
Published in The Journal of biological chemistry (07-03-1997)“…The two tandem phosphotyrosine interaction/phosphotyrosine binding (PID/PTB) domains of the Fe65 protein interact with the intracellular region of the…”
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Heat Shock Induces Preferential Translation of ERGIC-53 and Affects Its Recycling Pathway
Published in The Journal of biological chemistry (08-10-2004)“…ERGIC-53 is a lectin-like transport receptor protein, which recirculates between the ER and the Golgi complex and is required for the intracellular transport…”
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Detection and functional analysis of an SNP in the promoter of the human ferritin H gene that modulates the gene expression
Published in Gene (01-08-2006)“…The H ferritin promoter spans approximately 150 bp, upstream of the transcription start and is composed by two cis-elements in position -132 (A box) and -62…”
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Fe65, a Ligand of the Alzheimer's [beta]-Amyloid Precursor Protein, Blocks Cell Cycle Progression by Down-regulating Thymidylate Synthase Expression
Published in The Journal of biological chemistry (20-09-2002)“…The functions of the Alzheimer's [beta]-amyloid precursor protein (APP) and of its complex with the adaptor protein Fe65 are still unknown. We have…”
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DNA-binding protein Pur alpha and transcription factor YY1 function as transcription activators of the neuron-specific FE65 gene promoter
Published in Biochemical journal (15-11-1997)“…Fe65 is an adaptor protein that interacts with the Alzheimer beta-amyloid precursor protein and is expressed mainly in the neurons of several regions of the…”
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The DNA sequence encompassing the transcription start site of a TATA-less promoter contains enough information to drive neuron-specific transcription
Published in Nucleic acids research (25-11-1994)“…The FE65 gene encodes a nuclear protein of unknown function that is expressed in several areas of the rat nervous system during development and in the adult…”
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Extinction of retinol-binding protein gene expression in somatic cell-hybrids: Identification of the target sequences
Published in Nucleic acids research (01-01-1991)“…The Retinol-Binding Protein (RBP) is expressed primarily in the liver. The regulatory elements involved in its tissue-specific expression have been identified…”
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