Search Results - "Faranda, Adam"

The aging mouse lens transcriptome by Faranda, Adam P., Shihan, Mahbubul H., Wang, Yan, Duncan, Melinda K.

“…Abstract Age is a major risk factor for cataract (ARC). However, the influence of aging on the lens transcriptome is under studied. Lens epithelial (LEC) and…”
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Fibronectin has multifunctional roles in posterior capsular opacification (PCO) by Shihan, Mahbubul H., Kanwar, Mallika, Wang, Yan, Jackson, Erin E., Faranda, Adam P., Duncan, Melinda K.

“…Fibrotic posterior capsular opacification (PCO), one of the major complications of cataract surgery, occurs when lens epithelial cells (LCs) left behind post…”
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The effect of sex on the mouse lens transcriptome by Faranda, Adam P., Shihan, Mahbubul H., Wang, Yan, Duncan, Melinda K.

“…The transcriptome of mammalian tissues differs between males and females, and these differences can change across the lifespan, likely regulating known sexual…”
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ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment by Xiang, Jiawen, Pompetti, Anthony J, Faranda, Adam P, Wang, Yan, Novo, Samuel G, Li, David Wan-Cheng, Duncan, Melinda K

“…The late embryonic mouse lens requires the transcription factor ATF4 for its survival although the underlying mechanisms were unknown. Here, RNAseq analysis…”
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The Immediate Early Response of Lens Epithelial Cells to Lens Injury by Novo, Samuel G, Faranda, Adam P, Shihan, Mahbubul H, Wang, Yan, Garg, Ananya, Duncan, Melinda K

“…Cataracts are treated by lens fiber cell removal followed by intraocular lens (IOL) implantation into the lens capsule. While effective, this procedure leaves…”
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αVβ8 integrin targeting to prevent posterior capsular opacification by Shihan, Mahbubul H, Novo, Samuel G, Wang, Yan, Sheppard, Dean, Atakilit, Amha, Arnold, Thomas D, Rossi, Nicole M, Faranda, Adam P, Duncan, Melinda K

“…Fibrotic posterior capsular opacification (PCO), a major complication of cataract surgery, is driven by transforming growth factor-β (TGF-β). Previously, αV…”
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Butylated Hydroxytoluene Is a Ligand of Urinary Proteins Derived from Female Mice by KWAK, Jae, JOSUE, Jesusa, FARANDA, Adam, CURRAN OPIEKUN, Maryanne, PRETI, George, OSADA, Kazumi, YAMAZAKI, Kunio, BEAUCHAMP, Gary K

“…Mice secrete substantial amounts of protein, particularly proteins called the major urinary proteins (MUPs), in urine. One function of MUPs is to sequester…”
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Bioinformatic Workflows for Deriving Transcriptomic Points of Departure: Current status, Data Gaps, and Research Priorities by O’Brien, Jason, Mitchell, Constance, Auerbach, Scott, Doonan, Liam, Ewald, Jessica, Everett, Logan, Faranda, Adam, Johnson, Kamin, Reardon, Anthony, Rooney, John, Shao, Kan, Stainforth, Robert, Wheeler, Matthew, Dalmas Wilk, Deidre, Williams, Andrew, Yauk, Carole, Costa, Eduardo

“…Abstract There is a pressing need to increase the efficiency and reliability of toxicological safety assessment for protecting human health and the…”
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Aging, Aniridia, and Injury: Transcriptomic Perspectives on the Molecular Pathology of the Ocular Lens by Faranda, Adam P

“…By helping to focus incoming light, the lens of the eye has an essential role in the vertebrate visual system. Consisting of two basic cell types, the lens has…”
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Volatile organic compounds released by enzymatic reactions in raw nonpareil almond kernel by Kwak, Jae, Faranda, Adam, Henkin, Joshua M, Gallagher, Michelle, Preti, George, McGovern, Patrick E

“…Benzaldehyde is well recognized as the predominant aroma in bitter almond (Prunus dulcis var amara) and is released from amygdalin upon enzymatic hydrolysis…”
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Volatile biomarkers from human melanoma cells by Kwak, Jae, Gallagher, Michelle, Ozdener, Mehmet Hakan, Wysocki, Charles J., Goldsmith, Brett R., Isamah, Amaka, Faranda, Adam, Fakharzadeh, Steven S., Herlyn, Meenhard, Johnson, A.T. Charlie, Preti, George

“…•VOC profiles of melanoma and normal melanocytes cultured in vitro were examined.•SPME, GC/MS and single-stranded DNA-coated nanotube sensors were…”
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On the persistence of mouse urine odour to human observers: a review by Kwak, Jae, Jackson, Marcus, Faranda, Adam, Osada, Kazumi, Tashiro, Takuya, Mori, Kenji, Quan, Ying, Voznessenskaya, Vera V., Preti, George

“…To the human nose, mice produce unique, persistent and potent odour which is widely assumed to be derived mainly from their urine. In this review, we discuss…”
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Identifying Key Gene Sets in Metastatic Dormancy: Ontology Enrichment in Gene Expression Profiles from Selected Human Breast Cancer Patients by Pater-Faranda, Adam B

“…For approximately 20% of breast cancer patients, many years pass between initial remission and the emergence of distal metastases. These late recurrences are…”
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