Search Results - "Farajifard, Hamid"
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Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis
Published in Stem cell research & therapy (28-11-2023)“…The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the…”
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Immunopathogenesis of viral infections in neurological autoimmune disease
Published in BMC neurology (23-05-2023)“…Autoimmune diseases develop due to self-tolerance failure in recognizing self and non-self-antigens. Several factors play a role in inducing autoimmunity,…”
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An insight to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis; evidence from high-throughput data integration and meta-analysis
Published in Retrovirology (30-12-2019)“…Human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the central nervous system that…”
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Collagen II-primed Foxp3 Transduced T Cells Ameliorate Collagen-induced Arthritis in Rats: The Effect of Antigenic Priming on T Regulatory Cell Function
Published in Iranian journal of allergy, asthma, and immunology (01-08-2018)“…Regulatory T cells (Tregs) play a major role in the prevention of autoimmune diseases. Transfer of Foxp3 gene into conventional T cells converts their…”
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Congenital neutropenia and primary immunodeficiency diseases
Published in Critical reviews in oncology/hematology (01-01-2019)“…[Display omitted] Neutropenia is a dangerous and potentially fatal condition that renders patients vulnerable to recurrent infections. Its severity is…”
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Historical Cohort of Severe Congenital Neutropenia in Iran: Clinical Course, Laboratory Evaluation, Treatment, and Survival
Published in Journal of pediatric hematology/oncology (01-07-2023)“…Severe congenital neutropenia (SCN) is one of the primary immunodeficiency diseases developed by genetic alterations. Mutations in several genes including…”
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Historical Cohort of Severe Congenital Neutropenia in Iran: Clinical Course, Laboratory Evaluation, Treatment, and Survival
Published in Journal of pediatric hematology/oncology (10-04-2023)Get full text
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Protective and pathological roles of regulatory immune cells in human cytomegalovirus infection following hematopoietic stem cell transplantation
Published in Reviews in medical virology (01-07-2022)“…Human cytomegalovirus (HCMV) is ubiquitously prevalent. Immune system in healthy individuals is capable of controlling HCMV infection; however, HCMV can be…”
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Signaling factors potentially associated to the pathogenesis of Adult T-cell leukemia /lymphoma: A network-analysis and novel findings assessment
Published in Virus research (02-10-2022)“…•Five high-throughput data of ATLL were integrated and analyzed by systems biology.•The hsa-mir-146, 451, 31, and 125 might be implicated in ATLL…”
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Different roles of CXCR1 and CXCR2 in HTLV-1 carriers and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients
Published in Medical microbiology and immunology (01-10-2019)“…One of the prominent features of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the excessive recruitment of leukocytes to the central…”
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Prophylactic DNA vaccine targeting Foxp3+ regulatory T cells depletes myeloid-derived suppressor cells and improves anti-melanoma immune responses in a murine model
Published in Cancer Immunology, Immunotherapy (01-03-2018)“…Regulatory T cells (Treg) and myeloid-derived suppressor cells (MDSC) are the two important and interactive immunosuppressive components of the tumor…”
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Fludarabine‐based reduced‐intensity conditioning regimen for hematopoietic stem cell transplantation in pediatric patient with IL10 receptor deficiency
Published in Pediatric transplantation (01-03-2021)“…IL‐10R deficiency results in severe immune dysregulation. Herein, we describe the successful treatment of a girl aged 6.8 years with IL10R deficiency by using…”
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Effect of Early Bacillus Calmette-Guerin Vaccination of Pediatric Severe Combined Immunodeficiency Patients on the Outcome of Hematopoietic Stem Cell Transplantation Using a Reduced-Intensity Conditioning Regimen
Published in Transplantation and cellular therapy (01-03-2023)“…The eminence of Bacillus Calmette-Guerin (BCG) vaccine in newborn vaccination programs has been conspicuous throughout the years, especially in low-income…”
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In vitro study of HAX1 gene therapy by retro viral transduction as a therapeutic target in severe congenital neutropenia
Published in European cytokine network (Montrouge) (01-12-2018)“…Severe congenital neutropenia (SCN) is a primary immunodeficiency disease in which a number of underlying gene defects are responsible for abnormalities in…”
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Role of IL-21 in HTLV-1 infections with emphasis on HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Published in Medical microbiology and immunology (01-06-2017)“…Interleukin-21 (IL-21) enhances the survival and cytotoxic properties of cytotoxic T cells (CTLs) and exhibits essential roles in controlling chronic viral…”
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Altered expression of CXCR3 and CCR6 and their ligands in HTLV‐1 carriers and HAM/TSP patients
Published in Journal of medical virology (01-08-2017)“…Recruitment of leukocytes by chemokines and chemokine receptors to CNS plays a crucial role in the induction of inflammatory response in HTLV‐1‐associated…”
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Development and validation of real-time RT-PCR method for assessing of IL-21 and IL-23 gene expression
Published in Clinical biochemistry (01-09-2011)Get full text
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Development of a real-time RT-PCR TaqMan assay for measurement of CXCR-1 and CXCR2 in HAM/TSP subjects
Published in Clinical biochemistry (01-09-2011)Get full text
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