Search Results - "Farahani, Rahele A."

Metabolic Syndrome Alters the Cargo of Mitochondria-Related microRNAs in Swine Mesenchymal Stem Cell-Derived Extracellular Vesicles, Impairing Their Capacity to Repair the Stenotic Kidney by Eirin, Alfonso, Lerman, Amir, Jordan, Kyra L., Tang, Hui, Zhu, Xiang-Yang, Farahani, Rahele A., Lerman, Lilach O.

“…Background. Coexisting metabolic syndrome (MetS) and renal artery stenosis (RAS) are linked to poor renal outcomes. Mesenchymal stem/stromal cell- (MSC-)…”
Get full text

Metabolic Syndrome Induces Epigenetic Alterations in Mitochondria-Related Genes in Swine Mesenchymal Stem Cells by Rajagopalan, Kamalnath S, Kazeminia, Sara, Glasstetter, Logan M, Farahani, Rahele A, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L, Chade, Alejandro R, Lerman, Amir, Lerman, Lilach O, Eirin, Alfonso

“…Autologous mesenchymal stem/stromal cells (MSCs) have demonstrated important therapeutic effects in several diseases. Cardiovascular risk factors may impair…”
Get full text

Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles Elicit Better Preservation of the Intra-Renal Microvasculature Than Renal Revascularization in Pigs with Renovascular Disease by Ferguson, Christopher M, Farahani, Rahele A, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L, Saadiq, Ishran M, Lerman, Amir, Lerman, Lilach O, Eirin, Alfonso

“…Percutaneous transluminal renal angioplasty (PTRA) confers clinical and mortality benefits in select 'high-risk' patients with renovascular disease (RVD)…”
Get full text

The Effect of Glucagon-Like Peptide 1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion by Farahani, Rahele A, Egan, Aoife M, Welch, Andrew A, Laurenti, Marcello C, Cobelli, Claudio, Dalla Man, Chiara, Vella, Adrian

“…Data from transgenic rodent models suggest that glucagon acts as an insulin secretagogue by signaling through the glucagon-like peptide 1 receptor (GLP-1R)…”
Get full text

Very-Early-Onset Inflammatory Bowel Disease in a Patient With Junctional Epidermolysis Bullosa With a Homozygous Mutation in the α6 Integrin Gene (ITGA6) by Vahidnezhad, Hassan, Youssefian, Leila, Anbardar, Mohammad Hossein, Zeinali, Sirous, Farahani, Rahele A, Uitto, Jouni

Get full text

1646-P: The Effect of Glucagon-Like Peptide-1 Receptor Blockade and Acute Insulin Resistance on Islet Function and Glucose Metabolism in People without Diabetes by ZEINI, MAYA, FARAHANI, RAHELE A., WELCH, ANDREW A., LAURENTI, MARCELLO C., COBELLI, CLAUDIO, DALLA MAN, CHIARA, EGAN, AOIFE M., VELLA, ADRIAN

“…Intra-islet Glucagon-Like Peptide-1 (GLP-1) is increased by islet inflammation and diabetes. GLP-1 Receptor (GLP1R) blockade with exendin-9,39 impairs fasting…”
Get full text

1547-P: The Differential Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucose Metabolism in People With and Without Type 2 Diabetes by WELCH, ANDREW A., FARAHANI, RAHELE A., ZEINI, MAYA, EGAN, AOIFE M., LAURENTI, MARCELLO C., COBELLI, CLAUDIO, DALLA MAN, CHIARA, VELLA, ADRIAN

“…Glucagon-Like Peptide-1 (GLP-1) is present within the islet but the effects of GLP-1 Receptor (GLP1R) blockade on islet function in humans remains unknown. To…”
Get full text

36-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on the ß-Cell Response to Glucagon Bolus in People With and Without Type 2 Diabetes by EGAN, AOIFE M., ZEINI, MAYA, WELCH, ANDREW A., FARAHANI, RAHELE A., LAURENTI, MARCELLO C., COBELLI, CLAUDIO, DALLA MAN, CHIARA, VELLA, ADRIAN

“…Glucagon acts as an insulin secretagogue in part via the glucagon-like peptide-1 receptor (GLP1R) expressed on β-cells. Type 2 diabetes (DM2) is characterized…”
Get full text

Whole-Transcriptome Analysis by RNA Sequencing for Genetic Diagnosis of Mendelian Skin Disorders in the Context of Consanguinity by Youssefian, Leila, Saeidian, Amir Hossein, Palizban, Fahimeh, Bagherieh, Atefeh, Abdollahimajd, Fahimeh, Sotoudeh, Soheila, Mozafari, Nikoo, Farahani, Rahele A, Mahmoudi, Hamidreza, Babashah, Sadegh, Zabihi, Masoud, Zeinali, Sirous, Fortina, Paolo, Salas-Alanis, Julio C, South, Andrew P, Vahidnezhad, Hassan, Uitto, Jouni

“…Abstract Background Among the approximately 8000 Mendelian disorders, >1000 have cutaneous manifestations. In many of these conditions, the underlying mutated…”
Get full text

Glucagon-like peptide-1 receptor blockade impairs islet secretion and glucose metabolism in humans by Welch, Andrew A, Farahani, Rahele A, Egan, Aoife M, Laurenti, Marcello C, Zeini, Maya, Vella, Max, Bailey, Kent R, Cobelli, Claudio, Dalla Man, Chiara, Matveyenko, Aleksey, Vella, Adrian

“…BACKGROUNDProglucagon can be processed to glucagon-like peptide1 (GLP-1) within the islet, but its contribution to islet function in humans remains unknown. We…”
Get full text

1325-P: Modulation of Overnight Free Fatty Acid and Glucose Concentrations and Their Effect on Postprandial Islet Function and Glucose Metabolism by WELCH, ANDREW A., SCHEMBRI WISMAYER, DANIEL, EGAN, AOIFE M., FARAHANI, RAHELE A., LAURENTI, MARCELLO C., COBELLI, CLAUDIO, DALLA MAN, CHIARA, VELLA, ADRIAN

“…Individuals with prediabetes can be classified by fasting and glucose tolerance status. Previously we observed that elevated fasting Free Fatty Acids (FFA) are…”
Get full text

358-OR: The Effect of Glucagon-Like Peptide-1 Receptor Blockade on Glucagon-Induced Stimulation of Insulin Secretion by FARAHANI, RAHELE A., EGAN, AOIFE M., WELCH, ANDREW A., LAURENTI, MARCELLO C., COBELLI, CLAUDIO, DALLA MAN, CHIARA, VELLA, ADRIAN

“…Data from transgenic rodent models suggest that glucagon acts as an insulin secretagogue by signalling through the Glucagon-Like Peptide-1 Receptor (GLP1R)…”
Get full text

Percutaneous transluminal renal angioplasty attenuates poststenotic kidney mitochondrial damage in pigs with renal artery stenosis and metabolic syndrome by Farahani, Rahele A., Afarideh, Mohsen, Zhu, Xiang‐Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Ferguson, Christopher M., Lerman, Amir, Textor, Stephen C., Lerman, Lilach O., Eirin, Alfonso

“…Percutaneous transluminal renal angioplasty (PTRA) has been used to treat renovascular disease (RVD), a chronic condition characterized by renal ischemia and…”
Get full text

Renal Revascularization Attenuates Myocardial Mitochondrial Damage and Improves Diastolic Function in Pigs with Metabolic Syndrome and Renovascular Hypertension by Farahani, Rahele A., Yu, Shasha, Ferguson, Christopher M., Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Herrmann, Sandra M., Chade, Alejandro R., Lerman, Amir, Lerman, Lilach O., Eirin, Alfonso

“…Percutaneous transluminal renal angioplasty (PTRA) may improve cardiac function in renovascular hypertension (RVH), but its effect on the biological mechanisms…”
Get full text

Renal Revascularization Attenuates Myocardial Mitochondrial Damage and Improves Diastolic Function in Pigs with Metabolic Syndrome and Renovascular Hypertension: TH-OR44 by Eirin, Alfonso, Farahani, Rahele A., Ferguson, Christopher M., Zhu, Xiang yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Herrmann, Sandra, Chade, Alejandro R., Lerman, Amir, Lerman, Lilach O.

Get full text

Percutaneous transluminal renal angioplasty attenuates post-stenotic kidney mitochondrial damage in pigs with renal artery stenosis and metabolic syndrome by Farahani, Rahele A., Afarideh, Mohsen, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Ferguson, Christopher M., Lerman, Amir, Textor, Stephen C., Lerman, Lilach O., Eirin, Alfonso

Get full text