Search Results - "Farah, Zackariah"

Integrative Drug Screening and Multiomic Characterization of Patient-derived Bladder Cancer Organoids Reveal Novel Molecular Correlates of Gemcitabine Response by Merrill, Nathan M., Kaffenberger, Samuel D., Bao, Liwei, Vandecan, Nathalie, Goo, Laura, Apfel, Athena, Cheng, Xu, Qin, Zhaoping, Liu, Chia-Jen, Bankhead, Armand, Wang, Yin, Kathawate, Varun, Tudrick, Lila, Serhan, Habib A., Farah, Zackariah, Ellimoottil, Chad, Hafez, Khaled S., Herrel, Lindsey A., Montgomery, Jeffrey S., Morgan, Todd M., Salami, Simpa S., Weizer, Alon Z., Ulintz, Peter J., Day, Mark L., Soellner, Matthew B., Palmbos, Phillip L., Merajver, Sofia D., Udager, Aaron M.

“…We utilize patient tumor material to generate short-term bladder cancer patient–derived organoid (PDO) cultures for ex vivo drug testing, show that these PDOs…”
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Abstract 7091: Significance of the tryptophan catabolism pathway in triple-negative breast cancer shows potential targets in certain subsets relating to the serine pathway by Jeon, Jin Heon, Achreja, Abhinav, Slayton, Mark, Animasahun, Olamide, Nenwani, Minal, Paserba, Miya, Farah, Zackariah, Merajver, Sofia D., Nagrath, Deepak

“…Background: Breast cancer (BC) is the most prevalent form of cancer worldwide, encompassing 12.5% of all forms of cancers with the fifth highest mortality…”
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Abstract 431: Malic enzyme 2 inhibition reveals metabolic vulnerability in serine-dependent triple-negative breast cancer by Slayton, Mark D., Farah, Zackariah A., Jeon, Jin Heon, Achreja, Abhinav, Krinkel, Ben, Nilaj, Brisilda, Eu, Yi-Hsien, Sung, Justin, Rosenfeld, Alyssa, Lui, Alisa, Collard, Mason, Bao, Liwei, Cheng, Xu, Kleer, Celina, Loomes, Kerry, Nagrath, Deepak, Merajver, Sofia D.

“…Background & Hypothesis: Treatments for triple-negative breast cancer (TNBC) are limited to chemotherapy, PARP inhibitors and immunotherapies. Tumor metabolism…”
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Abstract 3921: Malic enzyme 2 identified as metabolic target in triple-negative breast cancers with increased serine biosynthesis by Slayton, Mark D., Jeon, Jin Heon, Achreja, Abhinav, Farah, Zackariah A., Nilaj, Brisilda, Eu, Yi-Hsien, Lui, Alisa, Collard, Mason, Bao, Liwei, Kleer, Celina, Nagrath, Deepak, Merajver, Sofia D.

“…Background & Hypothesis: Triple-negative breast cancer (TNBC) is a difficult to treat and deadly form of breast cancer. Pyruvate is an essential intermediate…”
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Abstract A009: Integrative drug screening and multi-omic characterization of patient-derived bladder cancer organoids reveals novel molecular correlates of chemotherapy response by Merrill, Nathan M., Kaffenberger, Samuel D., Bao, Liwei, Vandecan, Nathalie, Goo, Laura E., Apfel, Athena, Cheng, Xu, Qin, Zhaoping, Liu, Chia-Jen, Bankhead, Armand, Wang, Yin, Kathawate, Varun, Tudrick, Lila, Serhan, Habib, Farah, Zackariah, Ellimoottil, Chad, Hafez, Khaled S., Herrel, Lindsey A., Montgomery, Jeffrey S., Morgan, Todd M., Salami, Simpa S., Weizer, Alon Z., Ulintz, Peter J., Day, Mark L., Soellner, Matthew B., Palmbos, Phillip L., Merajver, Sofia D., Udager, Aaron M.

“…Introduction: Predicting response to therapy for each patient’s tumor is critical to improving long-term outcomes for muscle-invasive bladder cancer (MIBC)…”
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