Search Results - "Farago, Danilo Nascimento"
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Optimization of benzenesulfonyl derivatives as anti-Trypanosomatidae agents: Structural design, synthesis, and pharmacological assessment against Trypanosoma cruzi and Leishmania infantum
Published in Bioorganic & medicinal chemistry (01-05-2024)“…[Display omitted] Leishmaniasis and Chagas disease are neglected tropical diseases caused by Trypanosomatidae parasites. Given the numerous limitations…”
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Discovery and structural optimization of a new series of N-acyl-2-aminobenzothiazole as inhibitors of Zika virus
Published in Bioorganic & medicinal chemistry (15-11-2023)“…[Display omitted] •• Design, synthesis, and antiviral activity of N-acyl-2-aminobenzothiazole derivatives.•• The N-acyl-2-aminobenzothiazole class is a…”
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Discovery of Arylpiperazines with Broad-Spectrum Antimicrobial Activity and Favorable Pharmacokinetic Profiles
Published in Chemistry & biodiversity (26-09-2024)“…Microorganisms can induce diseases with significant clinical implications for human health. Multidrug-resistant microorganisms have been on the rise worldwide…”
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Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum
Published in Chemical biology & drug design (01-04-2024)“…An early exploration of the benzothiazole class against two kinetoplastid parasites, Leishmania infantum and Trypanosoma cruzi, has been performed after the…”
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