Search Results - "Farag, Rania"
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Hesperetin mitigates sorafenib-induced cardiotoxicity in mice through inhibition of the TLR4/NLRP3 signaling pathway
Published in PloS one (09-08-2022)“…Sorafenib is an oral multi-kinase receptor inhibitor that targets various signaling pathways. It is used as the first line of treatment in advanced…”
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Design, synthesis, biological evaluation, and docking studies of novel triazolo[4,3- b ]pyridazine derivatives as dual c-Met/Pim-1 potential inhibitors with antitumor activity
Published in RSC advances (18-09-2024)“…Interest has been piqued in c-Met and Pim-1, potential new cancer treatment targets. A variety of triazolo[4,3- ]pyridazine derivatives were synthesized to…”
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Antitumor and multikinase inhibition activities of some synthesized coumarin and benzofuran derivatives
Published in Archiv der Pharmazie (Weinheim) (01-06-2022)“…Two new series of coumarin and benzofuran derivatives were designed, synthesized, and assessed for their in vitro and in vivo antitumor activities against…”
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Repurposing of nifedipine loaded in situ ophthalmic gel as a novel approach for glaucoma treatment
Published in Biomedicine & pharmacotherapy (01-10-2021)“…Glaucoma is a chronic eye disease characterized by elevated intraocular pressure (IOP) which causes severe complications to the eyes and may lead to vision…”
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Reduction of intraocular pressure using timolol orally dissolving strips in the treatment of induced primary open‐angle glaucoma in rabbits
Published in Journal of pharmacy and pharmacology (01-05-2020)“…Objective To enhance bioavailability of timolol (TML) and utilize alternatives for traditional eye drops for more patient compliance, this study was aiming to…”
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Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Hydroxyzine HCL (HHCL) is an antihistamine, used for the treatment of allergic skin conditions. The purpose of this study was to achieve a dual phase drug…”
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Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles
Published in Scientific reports (08-09-2022)“…Resveratrol (RSV), a non-flavonoid stilbene polyphenol, possesses anti-carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN…”
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Safety and efficacy of eye drops from umbilical cord blood platelet lysate to treat resistant corneal ulcer
Published in Medical hypothesis, discovery and innovation in ophthalmology (03-02-2023)“…Background: Umbilical cord blood (UCB) is a novel treatment of resistant corneal ulcers owing to the unique anti-inflammatory molecules and growth factors it…”
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Combined umbilical cord patching with amniotic membrane graft for corneal surface reconstruction
Published in Medical hypothesis, discovery and innovation in ophthalmology (03-12-2022)“…Umbilical cord patch (UCP) grafts have been successfully used for glaucoma shunt tube coverage and conjunctival surface reconstruction. In recent years, the…”
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Optimization and clinical evaluation of hyaluronic acid proniosome loaded in-situ gel for the management of recurrent aphthous stomatitis
Published in Journal of drug delivery science and technology (01-10-2024)“…Recurrent aphthous stomatitis (RAS) is a frequent unpleasant oral condition that causes ulcers. Hyaluronic acid (HY) is an inherent polymer owing antioxidant,…”
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Serum levels of chemerin, apelin, vaspin, and omentin-1 in obese type 2 diabetic Egyptian patients with coronary artery stenosis
Published in Canadian journal of physiology and pharmacology (01-01-2018)“…Cardiovascular diseases (CVD) are the leading cause of death in the diabetic population. Obesity is a serious problem that has been linked with CVD and…”
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Design, synthesis, biological evaluation, and docking studies of novel (imidazol-5-yl)pyrimidine-based derivatives as dual BRAFV600E/p38α inhibitors
Published in European journal of medicinal chemistry (05-04-2021)“…The synergistic effect of dual inhibition of serine/threonine protein kinases that are involved in the same signalling pathway of the diseases can exert…”
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The Role of Medical Image Modalities and AI in the Early Detection, Diagnosis and Grading of Retinal Diseases: A Survey
Published in Bioengineering (Basel) (01-08-2022)“…Traditional dilated ophthalmoscopy can reveal diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), diabetic macular edema…”
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Visumax femtolasik versus Moria M2 microkeratome in mild to moderate myopia: efficacy, safety, predictability, aberrometric changes and flap thickness predictability
Published in BMC ophthalmology (17-07-2017)“…This is an interventional prospective clinical study which was conducted to evaluate the efficacy, safety, predictability, ocular aberrations, and flap…”
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A Computer-Aided Diagnostic System for Diabetic Retinopathy Based on Local and Global Extracted Features
Published in Applied sciences (01-08-2022)“…Diabetic retinopathy (DR) is a major public health problem and the leading cause of vision loss in the working age population. This paper presents a novel deep…”
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Simultaneous versus Sequential Accelerated Corneal Collagen Cross-Linking and Wave Front Guided PRK for Treatment of Keratoconus: Objective and Subjective Evaluation
Published in Journal of Ophthalmology (01-01-2016)“…Aim. To compare objective and subjective outcome after simultaneous wave front guided (WFG) PRK and accelerated corneal cross-linking (CXL) in patients with…”
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Outcomes of bimanual microincision cataract surgery and 2.2-mm coaxial phacoemulsification
Published in Journal of Egyptian ophthalmological society (01-04-2018)“…Purpose To compare the efficacy and safety outcomes of bimanual microincision cataract surgery (B-MICS) versus 2.2-mm coaxial phacoemulsification (C-MICS)…”
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Design, synthesis, biological evaluation, and docking studies of novel triazolo4,3-bpyridazine derivatives as dual c-Met/Pim-1 potential inhibitors with antitumor activity
Published in RSC advances (18-09-2024)“…Interest has been piqued in c-Met and Pim-1, potential new cancer treatment targets. A variety of triazolo[4,3-b]pyridazine derivatives were synthesized to…”
Get full text
Journal Article -
19
Physiological responses of the eustigmatophycean Nannochloropsis salina to aqueous diesel fuel pollution
Published in Oceanologia (01-01-2005)“…The marine eustigmatophycean microalga Nannochloropsis(Monallantus) salina Hibberd was cultivated in a batchculture in the presence of various concentrations…”
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Omega-3 modulates anxiety and improves autistic like features induced by high fat diet but not valproate
Published in Neurology, psychiatry, and brain research (01-09-2019)“…•A relationship existed between neurodevelopmental disorder (autism) and maternal consumption of high fat diet (HFD)•Omega-3 deficient diet is linked to the…”
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