Search Results - "Faraci, M M"

Protecting against vascular disease in brain by Faraci, Frank M

“…Endothelial cells exert an enormous influence on blood vessels throughout the circulation, but their impact is particularly pronounced in the brain. New…”
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Cerebral Vascular Disease and Neurovascular Injury in Ischemic Stroke by Hu, Xiaoming, De Silva, T Michael, Chen, Jun, Faraci, Frank M

“…The consequences of cerebrovascular disease are among the leading health issues worldwide. Large and small cerebral vessel disease can trigger stroke and…”
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Impact of Hypertension on Cognitive Function: A Scientific Statement From the American Heart Association by Iadecola, Costantino, Yaffe, Kristine, Biller, José, Bratzke, Lisa C, Faraci, Frank M, Gorelick, Philip B, Gulati, Martha, Kamel, Hooman, Knopman, David S, Launer, Lenore J, Saczynski, Jane S, Seshadri, Sudha, Zeki Al Hazzouri, Adina

“…BACKGROUND—Age-related dementia, most commonly caused by Alzheimer disease or cerebrovascular factors (vascular dementia), is a major public health threat…”
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The role of oxidative stress and NADPH oxidase in cerebrovascular disease by Chrissobolis, Sophocles, Faraci, Frank M

“…The study of reactive oxygen species (ROS) and oxidative stress remains a very active area of biological research, particularly in relation to cellular…”
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Reactive oxygen species: influence on cerebral vascular tone by Faraci, Frank M

“…Departments of Internal Medicine and Pharmacology and Cardiovascular Center, Carver College of Medicine, University of Iowa, Iowa City, Iowa Reactive oxygen…”
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Free radical biology of the cardiovascular system by Chen, Alex F, Chen, Dan-Dan, Daiber, Andreas, Faraci, Frank M, Li, Huige, Rembold, Christopher M, Laher, Ismail

“…Most cardiovascular diseases (CVDs), as well as age-related cardiovascular alterations, are accompanied by increases in oxidative stress, usually due to…”
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Association between oral and fecal microbiome dysbiosis and treatment complications in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation by Faraci, M., Bonaretti, C., Dell’Orso, G., Pierri, F., Giardino, S., Angiero, F., Blasi, S., Farronato, G., Di Marco, E., Trevisiol, A., Olcese, E., Rufino, L., Squillario, M., Biassoni, R.

“…The oral and gastrointestinal mucosae represent the main targets of the toxic effect of chemo and/or radiotherapy administered during the conditioning regimen…”
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Role of Nox isoforms in angiotensin II-induced oxidative stress and endothelial dysfunction in brain by Chrissobolis, Sophocles, Banfi, Botond, Sobey, Christopher G, Faraci, Frank M

“…Angiotensin II (Ang II) promotes vascular disease through several mechanisms including by producing oxidative stress and endothelial dysfunction. Although…”
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Nox2-Derived Superoxide Contributes to Cerebral Vascular Dysfunction in Diet-Induced Obesity by LYNCH, Cynthia M, KINZENBAW, Dale A, XUNXHENG CHEN, SHANSHAN ZHAN, MEZZETTI, Erin, FILOSA, Jessica, ERGUL, Adviye, FAULKNER, Jessica L, FARACI, Frank M, DIDION, Sean P

“…Obesity is an increasing epidemic worldwide; however, little is known about effects of obesity produced by high-fat diet (HFD) on the cerebral circulation. The…”
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Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation by Claassen, Jurgen A H R, Thijssen, Dick H J, Panerai, Ronney B, Faraci, Frank M

“…Brain function critically depends on a close matching between metabolic demands, appropriate delivery of oxygen and nutrients, and removal of cellular waste…”
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Brain endothelium: a nexus for cerebral small vessel disease by Dichgans, Martin, Faraci, Frank M

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Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function by De Silva, T Michael, Kinzenbaw, Dale A, Modrick, Mary L, Reinhardt, Lindsey D, Faraci, Frank M

“…Rho kinase (ROCK) has been implicated in physiological and pathophysiological processes, including regulation of vascular function. ROCK signaling is thought…”
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Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia by Dayal, Sanjana, Baumbach, Gary L, Arning, Erland, Bottiglieri, Teodoro, Faraci, Frank M, Lentz, Steven R

“…There is an emerging consensus that hyperhomocysteinemia is an independent risk factor for cerebral vascular disease and that homocysteine-lowering therapy…”
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Pregnancy and pregnancy outcomes after hematopoietic stem cell transplantation in childhood: a cross-sectional survey of the EBMT Pediatric Diseases Working Party by Diesch-Furlanetto, T, Rovó, A, Galimard, J E, Szinnai, G, Dalissier, A, Sedlacek, P, Bodova, I, Roussou, V K, Gibson, B E, Poiré, X, Fagioli, F, Pichler, H, Faraci, M, Gumy-Pause, F G, Dalle, J H, Balduzzi, A, Bader, P, Corbacioglu, S

“…STUDY QUESTIONWhat are the characteristics of patients with conceptions transplanted in childhood and adolescence? SUMMARY ANSWERInsemination and conception…”
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Vascular Protection: Superoxide Dismutase Isoforms in the Vessel Wall by Faraci, Frank M, Didion, Sean P

“…Blood vessels express 3 isoforms of superoxide dismutase (SOD)cytosolic or copper-zinc SOD (CuZn-SOD), manganese SOD (Mn-SOD) localized in mitochondria, and an…”
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Chronic aldosterone administration causes Nox2-mediated increases in reactive oxygen species production and endothelial dysfunction in the cerebral circulation by Chrissobolis, Sophocles, Drummond, Grant R, Faraci, Frank M, Sobey, Christopher G

“…OBJECTIVES:An elevated plasma aldosterone level is an independent cardiovascular risk factor. Although excess aldosterone promotes cardiovascular disease, no…”
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Regulation of the Cerebral Circulation: Role of Endothelium and Potassium Channels by FARACI, FRANK M, HEISTAD, DONALD D

“…FRANK M. FARACI AND DONALD D. HEISTAD Departments of Internal Medicine and Pharmacology, Cardiovascular Center and Center on Aging, University of Iowa College…”
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IL-6 Deficiency Protects Against Angiotensin II–Induced Endothelial Dysfunction and Hypertrophy by Schrader, Laura I, Kinzenbaw, Dale A, Johnson, Andrew W, Faraci, Frank M, Didion, Sean P

“…OBJECTIVE—The goal of this study was to test the hypothesis that IL-6 mediates the increases in superoxide, vascular hypertrophy, and endothelial dysfunction…”
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Angiotensin II‐induced endothelial dysfunction: Impact of sex, genetic background, and rho kinase by Kinzenbaw, Dale A., Langmack, Lucy, Faraci, Frank M.

“…The renin‐angiotensin system (RAS) contributes to vascular disease with multiple cardiovascular risk factors including hypertension. As a major effector within…”
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Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-Kinase by Pelham, Christopher J., Ketsawatsomkron, Pimonrat, Groh, Séverine, Grobe, Justin L., de Lange, Willem J., Ibeawuchi, Stella-Rita C., Keen, Henry L., Weatherford, Eric T., Faraci, Frank M., Sigmund, Curt D.

“…Dominant-negative (DN) mutations in the nuclear hormone receptor peroxisome proliferator-activated receptor-γ (PPARγ) cause hypertension by an unknown…”
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