Search Results - "Farías, A."

Herpes Simplex Virus Type 1 Infection of the Central Nervous System: Insights Into Proposed Interrelationships With Neurodegenerative Disorders by Duarte, Luisa F, Farías, Mónica A, Álvarez, Diana M, Bueno, Susan M, Riedel, Claudia A, González, Pablo A

“…Herpes simplex virus type 1 (HSV-1) is highly prevalent in humans and can reach the brain without evident clinical symptoms. Once in the central nervous system…”
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Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches by Morales, Inelia, Guzmán-Martínez, Leonardo, Cerda-Troncoso, Cristóbal, Farías, Gonzalo A, Maccioni, Ricardo B

“…Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old. The molecular and cellular alterations that trigger this disease are…”
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Current Antivirals and Novel Botanical Molecules Interfering With Herpes Simplex Virus Infection by Álvarez, Diana M, Castillo, Estefanía, Duarte, Luisa F, Arriagada, José, Corrales, Nicolás, Farías, Mónica A, Henríquez, Adolfo, Agurto-Muñoz, Cristian, González, Pablo A

“…Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent within the human population and are characterized by lifelong infections and…”
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Impact of Hypoxia over Human Viral Infections and Key Cellular Processes by Reyes, Antonia, Duarte, Luisa F., Farías, Mónica A., Tognarelli, Eduardo, Kalergis, Alexis M., Bueno, Susan M., González, Pablo A.

“…Oxygen is essential for aerobic cells, and thus its sensing is critical for the optimal maintenance of vital cellular and tissue processes such as metabolism,…”
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Experimental Dissection of the Lytic Replication Cycles of Herpes Simplex Viruses in vitro by Ibáñez, Francisco J, Farías, Mónica A, Gonzalez-Troncoso, Maria P, Corrales, Nicolás, Duarte, Luisa F, Retamal-Díaz, Angello, González, Pablo A

“…Herpes simplex viruses type 1 and type 2 (HSV-1 and HSV-2) produce lifelong infections and are highly prevalent in the human population. Both viruses elicit…”
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Crosstalk Between Epithelial Cells, Neurons and Immune Mediators in HSV-1 Skin Infection by Duarte, Luisa F, Reyes, Antonia, Farías, Mónica A, Riedel, Claudia A, Bueno, Susan M, Kalergis, Alexis M, González, Pablo A

“…Herpes simplex virus type 1 (HSV-1) infection is highly prevalent in humans, with approximately two-thirds of the world population living with this virus…”
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Interplay between lipid metabolism, lipid droplets and RNA virus replication by Farías, Mónica A, Diethelm-Varela, Benjamín, Kalergis, Alexis M, González, Pablo A

“…Lipids play essential roles in the cell as components of cellular membranes, signaling molecules, and energy storage sources. Lipid droplets are cellular…”
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Interplay between Lipid Metabolism, Lipid Droplets, and DNA Virus Infections by Farías, Mónica A, Diethelm-Varela, Benjamín, Navarro, Areli J, Kalergis, Alexis M, González, Pablo A

“…Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and cholesterol esters that are coated by a phospholipid monolayer…”
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Pharmacological Induction of Heme Oxygenase-1 Impairs Nuclear Accumulation of Herpes Simplex Virus Capsids upon Infection by Ibáñez, Francisco J, Farías, Mónica A, Retamal-Díaz, Angello, Espinoza, Janyra A, Kalergis, Alexis M, González, Pablo A

“…Heme oxygenase-1 (HO-1) is an inducible enzyme that is expressed in response to physical and chemical stresses, such as ultraviolet radiation, hyperthermia,…”
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Pharmacological Inhibition of IRE-1 Alpha Activity in Herpes Simplex Virus Type 1 and Type 2-Infected Dendritic Cells Enhances T Cell Activation by Tognarelli, Eduardo I, Retamal-Díaz, Angello, Farías, Mónica A, Duarte, Luisa F, Palomino, Tomás F, Ibañez, Francisco J, Riedel, Claudia A, Kalergis, Alexis M, Bueno, Susan M, González, Pablo A

“…Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections are life-long and highly prevalent in the human population. These viruses persist in the…”
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Immunomodulatory markers and therapies for the management of infant respiratory syncytial virus infection by Loaiza, Ricardo A, Farías, Mónica A, Andrade, Catalina A, Ramírez, Mario A, Rodriguez-Guilarte, Linmar, Muñóz, José T, González, Pablo A, Bueno, Susan M, Kalergis, Alexis M

“…The human respiratory syncytial virus (hRSV) is one of childhood diseases' most common respiratory pathogens and is associated with lower respiratory tract…”
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Anti-herpetic Activity of Macrocystis pyrifera and Durvillaea antarctica Algae Extracts Against HSV-1 and HSV-2 by Castillo, Estefanía, Duarte, Luisa F, Corrales, Nicolas, Álvarez, Diana M, Farías, Mónica A, Henríquez, Adolfo, Smith, Patricio C, Agurto-Muñoz, Cristian, González, Pablo A

“…Herpes simplex viruses (HSVs) type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent in the human population, and the infections they produce are lifelong with…”
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Biomarkers for dementia in Latin American countries: Gaps and opportunities by Parra, Mario A., Orellana, Paulina, Leon, Tomas, Victoria, Cabello G., Henriquez, Fernando, Gomez, Rodrigo, Avalos, Constanza, Damian, Andres, Slachevsky, Andrea, Ibañez, Agustin, Zetterberg, Henrik, Tijms, Betty M., Yokoyama, Jennifer S., Piña‐Escudero, Stefanie D., Cochran, J. Nicholas, Matallana, Diana L., Acosta, Daisy, Allegri, Ricardo, Arias‐Suárez, Bianca P., Barra, Bernardo, Behrens, Maria Isabel, Brucki, Sonia M. D., Busatto, Geraldo, Caramelli, Paulo, Castro‐Suarez, Sheila, Contreras, Valeria, Custodio, Nilton, Dansilio, Sergio, Cruz‐Puebla, Myriam De, Souza, Leonardo Cruz, Diaz, Monica M., Duque, Lissette, Farías, Gonzalo A., Ferreira, Sergio T., Guimet, Nahuel Magrath, Kmaid, Ana, Lira, David, Lopera, Francisco, Meza, Beatriz Mar, Miotto, Eliane C., Nitrini, Ricardo, Nuñez, Alberto, O'Neill, Santiago, Ochoa, John, Pintado‐Caipa, Maritza, Resende, Elisa de Paula França, Risacher, Shannon, Rojas, Luz Angela, Sabaj, Valentina, Schilling, Lucas, Sellek, Allis F., Sosa, Ana, Takada, Leonel T., Teixeira, Antonio L., Unaucho‐Pilalumbo, Martha, Duran‐Aniotz, Claudia

“…Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the…”
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The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population by Guzmán-Martínez, Leonardo, Tapia, José Pablo, Farías, Gonzalo A, González, Andrea, Estrella, Matías, Maccioni, Ricardo B

“…The establishment of a molecular biomarker for early detection of Alzheimer's disease (AD) is critical for diagnosis and follow up of patients, and as a…”
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Cochlear dysfunction as an early biomarker of cognitive decline in normal hearing and mild hearing loss by Medel, Vicente, Delano, Paul H., Belkhiria, Chama, Leiva, Alexis, De Gatica, Cristina, Vidal, Victor, Navarro, Carlos F., Martín, Simon San, Martínez, Melissa, Gierke, Christine, García, Ximena, Cerda, Mauricio, Vergara, Rodrigo, Delgado, Carolina, Farías, Gonzalo A.

“…INTRODUCTION Age‐related hearing loss is an important risk factor for cognitive decline. However, audiogram thresholds are not good estimators of dementia risk…”
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Herpes simplex virus interference with immunity: Focus on dendritic cells by Farías, MA, Duarte, LF, Tognarelli, EI, González, PA

“…Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are highly prevalent in the human population. These viruses cause lifelong infections by establishing…”
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Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease by Slachevsky, Andrea, Guzmán-Martínez, Leonardo, Delgado, Carolina, Reyes, Pablo, Farías, Gonzalo A, Muñoz-Neira, Carlos, Bravo, Eduardo, Farías, Mauricio, Flores, Patricia, Garrido, Cristian, Becker, James T, López, Oscar L, Maccioni, Ricardo B

“…Intracellular neurofibrillary tangles are part of the core pathology of Alzheimer's disease (AD), which are mainly composed of hyperphosphorylated tau protein…”
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Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the central nervous system of mice suffering multiple sclerosis-like disease by Duarte, Luisa F., Villalobos, Verónica, Farías, Mónica A., Rangel-Ramírez, Ma. Andreina, González-Madrid, Enrique, Navarro, Areli J., Carbone-Schellman, Javier, Domínguez, Angélica, Alvarez, Alejandra, Riedel, Claudia A., Bueno, Susan M., Kalergis, Alexis M., Cáceres, Mónica, González, Pablo A.

“…Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease affecting the central nervous system (CNS) in animals that parallels several…”
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Heme Oxygenase-1 Expression in Dendritic Cells Contributes to Protective Immunity against Herpes Simplex Virus Skin Infection by Tognarelli, Eduardo I, Duarte, Luisa F, Farías, Mónica A, Cancino, Felipe A, Corrales, Nicolás, Ibáñez, Francisco J, Riedel, Claudia A, Bueno, Susan M, Kalergis, Alexis M, González, Pablo A

“…Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections are highly prevalent in the human population and produce mild to life-threatening diseases…”
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Limited Heme Oxygenase Contribution to Modulating the Severity of Salmonella enterica serovar Typhimurium Infection by Sebastián, Valentina P., Moreno-Tapia, Daniela, Melo-González, Felipe, Hernández-Cáceres, María P., Salazar, Geraldyne A., Pardo-Roa, Catalina, Farías, Mónica A., Vallejos, Omar P., Schultz, Bárbara M., Morselli, Eugenia, Álvarez-Lobos, Manuel M., González, Pablo A., Kalergis, Alexis M., Bueno, Susan M.

“…An important virulence trait of Salmonella enterica serovar Typhimurium (S. Typhimurium) is the ability to avoid the host immune response, generating systemic…”
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