Search Results - "Faqehi, Abdullah M. M"
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Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men
Published in The journal of clinical endocrinology and metabolism (01-05-2016)“…Context: Deficiency of aromatase, the enzyme that catalyzes the conversion of androgens to estrogens, is associated with insulin resistance in humans and mice…”
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Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors
Published in The journal of clinical endocrinology and metabolism (01-09-2019)“…Abstract Context Aromatase deficiency causes obesity and insulin resistance in aromatase knockout mice and humans with rare mutations of the aromatase gene…”
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Derivatization of estrogens enhances specificity and sensitivity of analysis of human plasma and serum by liquid chromatography tandem mass spectrometry
Published in Talanta (Oxford) (01-05-2016)“…Estrogens circulate at concentrations less than 20pg/mL in men and postmenopausal women, presenting analytical challenges. Quantitation by immunoassay is…”
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Derivatization with 2-hydrazino-1-methylpyridine enhances sensitivity of analysis of 5α-dihydrotestosterone in human plasma by liquid chromatography tandem mass spectrometry
Published in Journal of Chromatography A (15-03-2021)“…•Quantitative analysis of low abundance androgens in human plasma.•Quantitation of androgens over physiological range in men and post-menopausal women.•Use of…”
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Simultaneous pharmacokinetic and pharmacodynamic analysis of 5α-reductase inhibitors and androgens by liquid chromatography tandem mass spectrometry
Published in Talanta (Oxford) (01-01-2015)“…Benign prostatic hyperplasia and prostate cancer can be treated with the 5α-reductase inhibitors, finasteride and dutasteride, when pharmacodynamic biomarkers…”
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