Search Results - "Fanglin, Gong"
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AGILE platform: a deep learning powered approach to accelerate LNP development for mRNA delivery
Published in Nature communications (26-07-2024)“…Ionizable lipid nanoparticles (LNPs) are seeing widespread use in mRNA delivery, notably in SARS-CoV-2 mRNA vaccines. However, the expansion of mRNA therapies…”
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Poly-β-cyclodextrin Supramolecular Nanoassembly with a pH-Sensitive Switch Removing Lysosomal Cholesterol Crystals for Antiatherosclerosis
Published in Nano letters (24-11-2021)“…Cholesterol crystals (CCs), originally accumulating in the lysosome of cholesterol-laden cells, can aggravate the progression of atherosclerosis…”
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An elastase-inhibiting, plaque-targeting and neutrophil-hitchhiking liposome against atherosclerosis
Published in Acta biomaterialia (01-01-2024)“…Neutrophil extracellular traps (NETs) play a crucial role in the formation of vulnerable plaques and the development of atherosclerosis. Alleviating the…”
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The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis
Published in Journal of cardiovascular pharmacology (01-09-2022)“…Cardiovascular disease is responsible for the largest number of deaths worldwide, and atherosclerosis is the primary cause. Apoptotic cell accumulation in…”
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The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis
Published in Journal of cardiovascular pharmacology (06-06-2022)Get full text
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Nano-sponge-like liposomes remove cholesterol crystals for antiatherosclerosis
Published in Journal of controlled release (01-09-2022)“…Atherosclerotic cardiovascular diseases remain the leading causes of morbidity and mortality worldwide. Cholesterol crystals in atherosclerotic plaques play an…”
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Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy
Published in Advanced materials (Weinheim) (01-07-2024)“…The advancement of message RNA (mRNA) ‐based immunotherapies for cancer is highly dependent on the effective delivery of RNA (Ribonucleic) payloads using…”
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Tumor‐Tailored Ionizable Lipid Nanoparticles Facilitate IL‐12 Circular RNA Delivery for Enhanced Lung Cancer Immunotherapy (Adv. Mater. 29/2024)
Published in Advanced materials (Weinheim) (01-07-2024)“…Inhalable RNA Immunotherapy In article number 2400307, Bowen Li and co‐workers develop a tumor‐tailored lipid nanoparticle system to deliver IL‐12 circular RNA…”
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