Search Results - "Fangfang Yan"
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An overview of potential inhibitors targeting non-structural proteins 3 (PLpro and Mac1) and 5 (3CLpro/Mpro) of SARS-CoV-2
Published in Computational and structural biotechnology journal (01-01-2021)“…[Display omitted] Potential inhibitors against nsp3 and nsp5 of SARS-CoV-2 obtained through an extensive literature retrieval. There is an urgent need to…”
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scGWAS: landscape of trait-cell type associations by integrating single-cell transcriptomics-wide and genome-wide association studies
Published in Genome Biology (17-10-2022)“…The rapid accumulation of single-cell RNA sequencing (scRNA-seq) data presents unique opportunities to decode the genetically mediated cell-type specificity in…”
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Body iron stores and heme-iron intake in relation to risk of type 2 diabetes: a systematic review and meta-analysis
Published in PloS one (26-07-2012)“…Emerging evidence from biological and epidemiological studies has suggested that body iron stores and heme-iron intake may be related to the risk of type 2…”
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Insight into the Structures and Electrocatalytic Activities of PdAg Alloy on RGO in the Oxidation of Ethanol, Ethylene Glycol and Glycerol
Published in Catalysis letters (01-06-2021)“…The biorenewable alcohols are identified as the promising energy in fuel cells, but the lack of efficient catalysts limits the electricity output. Here, we…”
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Congestion-Aware Embedding of Heterogeneous Bandwidth Virtual Data Centers With Hose Model Abstraction
Published in IEEE/ACM transactions on networking (01-04-2017)“…Predictable network performance is critical for cloud applications and can be achieved by providing tenants a dedicated virtual data center (VDC) with…”
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Molecular Dynamics Exploration of Selectivity of Dual Inhibitors 5M7, 65X, and 65Z toward Fatty Acid Binding Proteins 4 and 5
Published in International journal of molecular sciences (23-08-2018)“…Designing highly selective inhibitors of fatty acid binding proteins 4 and 5 (FABP4 and FABP5) is of importance for treatment of some diseases related with…”
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Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages
Published in Frontiers in immunology (02-08-2022)“…Murine macrophages activated by the Toll-like receptor 4 agonist lipopolysaccharide (LPS) polarize to the M1 type by inducing proinflammatory marker proteins…”
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A systematic strategy for the investigation of vaccines and drugs targeting bacteria
Published in Computational and structural biotechnology journal (01-01-2020)“…[Display omitted] Infectious and epidemic diseases induced by bacteria have historically caused great distress to people, and have even resulted in a large…”
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NF-κB signaling and its relevance to the treatment of mantle cell lymphoma
Published in Journal of hematology and oncology (15-06-2018)“…Mantle cell lymphoma is an aggressive subtype of non-Hodgkin B cell lymphoma that is characterized by a poor prognosis determined by Ki67 and Mantle Cell…”
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Metabolomic profiles of A-type procyanidin dimer and trimer with gut microbiota in vitro
Published in Journal of functional foods (01-10-2021)“…[Display omitted] •The procyanidin metabolism by faecal microbiota in vitro was dissected based on metabolomics.•Procyanidin A1 and (epi)catechin were…”
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Corrigendum: Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages
Published in Frontiers in immunology (22-04-2024)“…[This corrects the article DOI: 10.3389/fimmu.2022.935692.]…”
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Single-cell multiomics decodes regulatory programs for mouse secondary palate development
Published in Nature communications (27-01-2024)“…Perturbations in gene regulation during palatogenesis can lead to cleft palate, which is among the most common congenital birth defects. Here, we perform…”
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An integrative, genomic, transcriptomic and network-assisted study to identify genes associated with human cleft lip with or without cleft palate
Published in BMC medical genomics (03-04-2020)“…Cleft lip with or without cleft palate (CL/P) is one of the most common congenital human birth defects. A combination of genetic and epidemiology studies has…”
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3'UTR of tobacco vein mottling virus regulates downstream GFP expression and changes in host gene expression
Published in Frontiers in microbiology (14-10-2024)“…Tobacco vein mottling virus (TVMV) is a member of the family . The 3' untranslated region (3'UTR) of viral genomic RNA has been reported to significantly…”
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Editorial: Progress of programmed cell death in antitumor immunity
Published in Frontiers in immunology (12-06-2023)Get full text
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Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma
Published in The Journal of clinical investigation (01-02-2023)“…Bruton's tyrosine kinase (BTK) is a proven target in mantle cell lymphoma (MCL), an aggressive subtype of non-Hodgkin lymphoma. However, resistance to BTK…”
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Bacillus velezensis SYL-3 suppresses Alternaria alternata and tobacco mosaic virus infecting Nicotiana tabacum by regulating the phyllosphere microbial community
Published in Frontiers in microbiology (28-07-2022)“…The occurrence of plant diseases is closely associated with the imbalance of plant tissue microecological environment. The regulation of the phyllosphere…”
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Integrative transcriptome analysis revealed the pathogenic molecular basis of Rhizoctonia solani AG-3 TB at three progressive stages of infection
Published in Frontiers in microbiology (11-10-2022)“…Rhizoctonia solani has a broad host range and results in significant losses in agricultural production. Here, an integrated transcriptomic analysis was…”
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A developmental stage specific network approach for studying dynamic transcription factor-microRNA co-regulation during craniofacial development
Published in Development (Cambridge) (01-01-2020)“…Craniofacial development is regulated through dynamic and complex mechanisms that involve various signaling cascades and gene regulations. Disruption of such…”
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