Search Results - "Fang, Zihui"
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Long-noncoding RNAs (lncRNAs) in drug metabolism and disposition, implications in cancer chemo-resistance
Published in Acta pharmaceutica Sinica. B (01-01-2020)“…Drug metabolism is an orchestrated process in which drugs are metabolized and disposed through a series of specialized enzymes and transporters. Alterations in…”
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Effect of Carbon-Ion Radiation on Drug Transporters Organic Anion Transporting Polypeptides in Breast Cancer Cells
Published in Radiation research (01-06-2017)“…Organic anion transporting polypeptides (OATPs) are a family of membrane uptake transporters that play important roles in absorption, distribution, metabolism…”
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Amino-terminal region of human organic anion transporting polypeptide 1B1 dictates transporter stability and substrate interaction
Published in Toxicology and applied pharmacology (01-09-2019)“…Organic anion transporting polypeptides (OATPs) are key players of drug absorption, distribution and excretion due to their broad substrate specificity, wide…”
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Transmembrane Domain 1 of Human Organic Anion Transporting Polypeptide 2B1 Is Essential for Transporter Function and Stability
Published in Molecular pharmacology (01-08-2018)“…Organic anion transporting polypeptides (OATPs, gene symbol ) are important membrane transporter proteins that mediate the uptake of wide ranges of endogenous…”
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Development of Bivalent mRNA Vaccines against SARS-CoV-2 Variants
Published in Vaccines (Basel) (26-10-2022)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected billions of individuals and is the cause of the current global coronavirus…”
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ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway
Published in Cancer research (Chicago, Ill.) (15-10-2020)“…Resistance to therapeutic drugs is a major challenge in the treatment of cancers, including breast cancer. Long noncoding RNAs (lncRNA) are known to have…”
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The intracellular NPxY motif is critical in maintaining the function and expression of human organic anion transporting polypeptide 1B1
Published in Biochimica et biophysica acta. Biomembranes (01-06-2019)“…Organic anion transporting polypeptides (OATPs, gene symbol SLCO) mediate sodium-independent transport of endogenous compounds such as bile salts, hormones and…”
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Abstract 2604: Constitutive activation of the human aryl hydrocarbon receptor in mice promotes hepatocarcinogenesis independent of its coactivator Gadd45b
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), or dioxin, is a potent liver cancer promoter through its sustained activation of the aryl hydrocarbon receptor…”
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Effect of major components of Tripterygium wilfordii Hook. f on the uptake function of organic anion transporting polypeptide 1B1
Published in Toxicology and applied pharmacology (15-01-2022)“…Organic anion transporting polypeptide 1B1 (OATP1B1), which is specifically expressed at the basolateral membrane of human hepatocytes, is well recognized as…”
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Amino‐terminal region plays an important role in transport function of human organic anion transporting polypeptide 1B1
Published in The FASEB journal (01-04-2018)“…Objective The family of organic anion transporting polypeptides (OATPs, gene symbol SLCO) mediates sodium‐independent transport of a wide variety of endogenous…”
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Oligomerization Study of Human Organic Anion Transporting Polypeptide 1B1
Published in Molecular pharmaceutics (06-02-2017)“…Organic anion-transporting polypeptides play important roles in the uptake of various endogenous and exogenous compounds. It has been proposed that OATP family…”
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12
The role of protein kinase C alpha translocation in radiation-induced bystander effect
Published in Scientific reports (11-05-2016)“…Ionizing radiation is a well known human carcinogen. Evidence accumulated over the past decade suggested that extranuclear/extracellular targets and events may…”
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13
Amino Acid Residues in the Putative Transmembrane Domain 11 of Human Organic Anion Transporting Polypeptide 1B1 Dictate Transporter Substrate Binding, Stability, and Trafficking
Published in Molecular pharmaceutics (07-12-2015)“…Organic anion transporting polypeptides (OATPs, gene symbol SLCO) are membrane proteins that mediate the sodium-independent transport of a wide range of…”
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14
Effects of sand-fixing and windbreak forests on wind flow: a synthesis of results from field experiments and numerical simulations
Published in 干旱区科学:英文版 (2017)“…Sand-fixing and windbreak forests are widely used to protect or/and improve the ecological environments in arid and semi-arid regions. A full understanding of…”
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Depositional environment of terrestrial petroleum source rocks and geochemical indicators in the Songliao Basin
Published in Science China. Earth sciences (01-09-2011)“…To determine geochemical indicators for depositional environment favored by terrestrial petroleum source rocks, we selected 40 source rock samples from the…”
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Effects of sand-fixing and windbreak forests on wind flow: a synthesis of results from field experiments and numerical simulations
Published in Journal of arid land (01-02-2017)“…Sand-fixing and windbreak forests are widely used to protect or/and improve the ecological environments in arid and semi-arid regions. A full understanding of…”
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17
Crude-oil hydrocarbon composition characteristics and oil viscosity prediction in the northern Songliao Basin
Published in Science China. Earth sciences (01-02-2014)“…Crude oil hydrocarbon composition characteristics and oil viscosity prediction are important bases in petroleum exploration. A total of 54 oil/heavy-oil…”
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Characteristics of the lower layer of sandstorms in the Minqin desert-oasis zone
Published in Science China. Earth sciences (01-05-2011)“…By measuring the sand-dust flux, vertical deposition, and the wind velocity throughout 19 sandstorms in the Minqin region, we quantitatively analyzed the…”
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Distribution and significance of C40+ alkanes in the extracts of Cretaceous source rocks from the Songliao Basin
Published in Science China. Earth sciences (2007)“…Source rock extracts and crude oils from the Songliao Basin were analyzed by high-temperature gas chromatography (HTGC), gas chromatography-mass spectrometry…”
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Bivariate association analysis for quantitative traits using generalized estimation equation
Published in Journal of genetics and genomics (01-12-2009)“…Quantitative traits often underlie risk for complex diseases. Many studies collect multiple correlated quantitative phenotypes and perform univariate analyses…”
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