Search Results - "Fang, Qijun"
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Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy
Published in Redox biology (01-08-2021)“…Activated microglia are an important type of innate immune cell in the brain, and they secrete inflammatory cytokines into the extracellular milieu, exert…”
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Tongbian formula alleviates slow transit constipation by increasing intestinal butyric acid to activate the 5-HT signaling
Published in Scientific reports (02-08-2024)“…Slow transit constipation (STC) is a long-lasting and prevalent intestinal condition, marked by hard, dry feces. The primary cause of STC may be attributed to…”
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Kaempferol alleviates LD-mitochondrial damage by promoting autophagy: Implications in Parkinson's disease
Published in Redox biology (01-05-2021)“…Emerging evidence indicates that unexpected lipid droplet (LD) deposition and peroxidation can accelerate organelle stress and plays a crucial role in the…”
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Neuronal NR4A1 deficiency drives complement-coordinated synaptic stripping by microglia in a mouse model of lupus
Published in Signal transduction and targeted therapy (18-02-2022)“…Neuropsychiatric lupus (NPSLE) is a frequent manifestation of systemic lupus erythematosus (SLE) that occurs in 40–90% of SLE patients; however, the underlying…”
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Regression analysis of insulin resistance and Chinese medicine syndromes in patients with diabetic kidney disease
Published in Zhongguo lin chuang yan jiu (01-12-2023)“…Objective To analyze the interdependent relationships between insulin resistance (IR) related indicators and Chinese medicine syndromes in patients with…”
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Clinical validation of p16/Ki‐67 dual‐stained cytology triage of HPV‐positive women: Results from the IMPACT trial
Published in International journal of cancer (01-02-2022)“…Triage strategies are needed for primary human papillomavirus (HPV)‐based cervical cancer screening to identify women requiring colposcopy/biopsy. We assessed…”
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Microglia orchestrate synaptic and neuronal stripping: Implication in neuropsychiatric lupus
Published in Journal of cellular and molecular medicine (01-04-2024)“…Systemic lupus erythematosus (SLE), a multifactorial autoimmune disease, can affect the brain and cause neuropsychiatric dysfunction, also named…”
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Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
Published in Aging (Albany, NY.) (24-12-2018)“…The kidney is a typical organ undergoing age and injury. Hyperoside is reported to be useful for preventing aging induced by D-galactose (D-gal). However,…”
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The IMproving Primary Screening And Colposcopy Triage trial: human papillomavirus, cervical cytology, and histopathologic results from the baseline and 1-year follow-up phase
Published in American journal of obstetrics and gynecology (01-09-2021)“…An increase in human papillomavirus test volumes is expected in the near future because human papillomavirus–based screening protocols are expected to become…”
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Routine Use of Adjunctive p16 Immunohistochemistry Improves Diagnostic Agreement of Cervical Biopsy Interpretation: Results From the CERTAIN Study
Published in The American journal of surgical pathology (01-08-2018)“…The diagnosis of squamous intraepithelial lesions in cervical tissue specimens is subject to substantial variability. Adjunctive immunohistochemical (IHC)…”
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The CERTAIN Study Results: Adjunctive p16 Immunohistochemistry Use in Cervical Biopsies According to LAST Criteria
Published in The American journal of surgical pathology (01-10-2021)“…The Lower Anogenital Squamous Terminology (LAST) Project recommends the use of p16 immunohistochemistry as an adjunct to morphologic assessment of cervical…”
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Correction for: Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
Published in Aging (Albany, NY.) (15-05-2024)Get full text
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Systematic literature review and testing of HER2 status in urothelial carcinoma (UC)
Published in Journal of clinical oncology (20-02-2023)“…556 Background: Recent clinical trials suggest an emerging role for HER2-targeted therapy in locally advanced and metastatic UC (LA/mUC). The prevalence of…”
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Analytical and clinical validation of PATHWAY Anti-HER-2/neu (4B5) antibody to assess HER2-low status for trastuzumab deruxtecan treatment in breast cancer
Published in Virchows Archiv : an international journal of pathology (01-06-2024)“…In DESTINY-Breast04 (DB-04), safety and efficacy of HER2-targeted antibody-drug conjugate (ADC) trastuzumab deruxtecan (T-DXd) in previously treated HER2-low…”
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Jinlida for Diabetes Prevention in Impaired Glucose Tolerance and Multiple Metabolic Abnormalities: The FOCUS Randomized Clinical Trial
Published in JAMA internal medicine (01-07-2024)“…Previous studies have shown that Jinlida (JLD) granules, an approved treatment for type 2 diabetes in China, can reduce blood glucose level, reduce glycated…”
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The IMPACT trial: human papillomavirus, cervical cytology and histopathological results from the baseline and 1-year follow-up phase
Published in American journal of obstetrics and gynecology (11-04-2021)“…An increase in human papillomavirus (HPV) test volumes is expected in the near future as HPV-based screening protocols are expected to become more broadly…”
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Hierarchical bayesian benchmark dose analysis
Published 01-01-2014“…An important objective in statistical risk assessment is estimation of minimum exposure levels, called Benchmark Doses (BMDs) that induce a pre-specified…”
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Dissertation -
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Bayesian model averaging for benchmark dose estimation
Published in Environmental and ecological statistics (01-03-2015)“…Benchmark dose estimation is widely used in various regulatory and industrial settings to estimate acceptable exposure levels to hazardous or toxic agents by…”
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Bayesian Benchmark Dose Analysis
Published 10-06-2014“…An important objective in environmental risk assessment is estimation of minimum exposure levels, called Benchmark Doses (BMDs) that induce a pre-specified…”
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Journal Article