Search Results - "Fang, Jingwen"

Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm by Guo, Chuang, Li, Bin, Ma, Huan, Wang, Xiaofang, Cai, Pengfei, Yu, Qiaoni, Zhu, Lin, Jin, Liying, Jiang, Chen, Fang, Jingwen, Liu, Qian, Zong, Dandan, Zhang, Wen, Lu, Yichen, Li, Kun, Gao, Xuyuan, Fu, Binqing, Liu, Lianxin, Ma, Xiaoling, Weng, Jianping, Wei, Haiming, Jin, Tengchuan, Lin, Jun, Qu, Kun

“…Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6) receptor, including tocilizumab, ameliorate lethal inflammatory…”
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Multi-Objective Sustainable Supply Chain Network Planning Based on Proximity Optimization With Hybrid Genetic Algorithm Variable Neighborhood Search Strategy by Huang, Pei, Fang, Jingwen

“…With the continuous expansion of the global market and the change of consumer preferences, the market demand presents a trend of complexity and diversity,…”
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Single-cell profiling of the human decidual immune microenvironment in patients with recurrent pregnancy loss by Guo, Chuang, Cai, Pengfei, Jin, Liying, Sha, Qing, Yu, Qiaoni, Zhang, Wen, Jiang, Chen, Liu, Qian, Zong, Dandan, Li, Kun, Fang, Jingwen, Lu, Fangting, Wang, Yanshi, Li, Daojing, Lin, Jun, Li, Lu, Zeng, Zhutian, Tong, Xianhong, Wei, Haiming, Qu, Kun

“…Maintaining homeostasis of the decidual immune microenvironment at the maternal–fetal interface is essential for placentation and reproductive success…”
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The gut microbiome promotes arsenic metabolism and alleviates the metabolic disorder for their mammal host under arsenic exposure by Chen, Linkang, Li, Chengji, Zhong, Xiaoting, Lai, Chengze, Zhang, Bin, Luo, Yu, Guo, Honghui, Liang, Keqing, Fang, Jingwen, Zhu, Xuan, Zhang, Jingjing, Guo, Lianxian

“…[Display omitted] •Normal gut microbiome and metabolics contributes to the fecal arsenic excretion and biotransformation.•Normal gut microbiome decreases the…”
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Comparative analysis of methodologies for detecting extrachromosomal circular DNA by Gao, Xuyuan, Liu, Ke, Luo, Songwen, Tang, Meifang, Liu, Nianping, Jiang, Chen, Fang, Jingwen, Li, Shouzhen, Hou, Yanbing, Guo, Chuang, Qu, Kun

“…Extrachromosomal circular DNA (eccDNA) is crucial in oncogene amplification, gene transcription regulation, and intratumor heterogeneity. While various…”
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Single-cell analysis of COVID-19, sepsis, and HIV infection reveals hyperinflammatory and immunosuppressive signatures in monocytes by Liu, Nianping, Jiang, Chen, Cai, Pengfei, Shen, Zhuoqiao, Sun, Wujianan, Xu, Hao, Fang, Minghao, Yao, Xinfeng, Zhu, Lin, Gao, Xuyuan, Fang, Jingwen, Lin, Jun, Guo, Chuang, Qu, Kun

“…The mortality risk of coronavirus disease 2019 (COVID-19) patients has been linked to the cytokine storm caused by severe acute respiratory syndrome…”
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Circ_0025373 inhibits carbon black nanoparticles-induced malignant transformation of human bronchial epithelial cells by affecting DNA damage through binding to MSH2 by Zhang, Han, Lu, Wenfeng, Qiu, Lan, Li, Saifeng, Qiu, Liqiu, He, Mengnan, Chen, Xintong, Wang, Jiajing, Fang, Jingwen, Zhong, Chenghui, Lan, Meiqi, Xu, Xiaole, Zhou, Yun

“…[Display omitted] Carbon black nanoparticles (CBNPs) have been demonstrated to induce DNA damage in epithelial cells. However, the potential of the damage to…”
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Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19 by Guo, Chuang, Wu, Mingming, Huang, Beibei, Zhao, Rui, Jin, Linlin, Fu, Binqing, Wang, Ping, Wang, Dongyao, Zheng, Meijuan, Fang, Jingwen, Wei, Haiming, Qu, Kun, Ni, Fang

“…Natural killer (NK) cells are innate lymphoid cells that mediate antitumour and antiviral responses. However, very little is known about how ageing influences…”
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MicroRNA-10a/b inhibit TGF-β/Smad-induced renal fibrosis by targeting TGF-β receptor 1 in diabetic kidney disease by Li, Jinxiang, Yue, Shuling, Fang, Jingwen, Zeng, Junling, Chen, Siqi, Tian, Jianwei, Nie, Sheng, Liu, Xiaoting, Ding, Hanying

“…TGF-β/Smad signaling plays a vital role in the development of fibrosis in diabetic kidney disease (DKD). However, remedies targeting key elements in TGF-β/Smad…”
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APEC: an accesson-based method for single-cell chromatin accessibility analysis by Li, Bin, Li, Young, Li, Kun, Zhu, Lianbang, Yu, Qiaoni, Cai, Pengfei, Fang, Jingwen, Zhang, Wen, Du, Pengcheng, Jiang, Chen, Lin, Jun, Qu, Kun

“…The development of sequencing technologies has promoted the survey of genome-wide chromatin accessibility at single-cell resolution. However, comprehensive…”
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Menin enhances c-Myc-mediated transcription to promote cancer progression by Wu, Gongwei, Yuan, Mengqiu, Shen, Shengqi, Ma, Xiaoyu, Fang, Jingwen, Zhu, Lianbang, Sun, Linchong, Liu, Zhaoji, He, Xiaoping, Huang, De, Li, Tingting, Li, Chenchen, Wu, Jun, Hu, Xin, Li, Zhaoyong, Song, Libing, Qu, Kun, Zhang, Huafeng, Gao, Ping

“…Menin is an enigmatic protein that displays unique ability to either suppress or promote tumorigenesis in a context-dependent manner. The role for Menin to…”
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PIRCh-seq: functional classification of non-coding RNAs associated with distinct histone modifications by Fang, Jingwen, Ma, Qing, Chu, Ci, Huang, Beibei, Li, Lingjie, Cai, Pengfei, Batista, Pedro J, Tolentino, Karen Erisse Martin, Xu, Jin, Li, Rui, Du, Pengcheng, Qu, Kun, Chang, Howard Y

“…We develop PIRCh-seq, a method which enables a comprehensive survey of chromatin-associated RNAs in a histone modification-specific manner. We identify…”
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High Expression of Complement Components in the Kidneys of Type 2 Diabetic Rats With Diabetic Nephropathy by Huang, Yinqiong, Xu, Jinting, Wu, Xiaohong, Chen, Xiaoyu, Bai, Xuefeng, Zhuang, Yong, Fang, Jingwen, Lin, Xiahong

“…Diabetic nephropathy (DN) is the leading cause of end-stage failure of the kidneys; however, its pathogenesis remains unknown. This study assessed the…”
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Single-cell transcriptomic analysis of immune cell dynamics in the healthy human endometrium by Chen, Kaixing, Yu, Qiaoni, Sha, Qing, Wang, Junyu, Fang, Jingwen, Li, Xin, Shen, Xiaokun, Fu, Binqing, Guo, Chuang

“…The microenvironment of the endometrial immune system is crucial to the success of placental implantation and healthy pregnancy. However, the functionalities…”
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A single-cell landscape of pre- and post-menopausal high-grade serous ovarian cancer ascites by Chen, Wenying, Liu, Hanyuan, Huang, Xinya, Qian, Lili, Chen, Liang, Zhou, Yonggang, Liu, Yi, Liu, Yujie, Wang, Yingying, Zhang, Tianjiao, Zhou, Youyang, Fang, Jingwen, Yang, Jiaxuan, Ni, Fang, Guo, Chuang, Zhou, Ying

“…High-grade serous ovarian cancer (HGSOC) is a hormone-related cancer with high mortality and poor prognosis. Based on the transcriptome of 57,444 cells in…”
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Correction: Author Correction: Menin enhances c-Myc-mediated transcription to promote cancer progression by Wu, Gongwei, Yuan, Mengqiu, Shen, Shengqi, Ma, Xiaoyu, Fang, Jingwen, Zhu, Lianbang, Sun, Linchong, Liu, Zhaoji, He, Xiaoping, Huang, De, Li, Tingting, Li, Chenchen, Wu, Jun, Hu, Xin, Li, Zhaoyong, Song, Libing, Qu, Kun, Zhang, Huafeng, Gao, Ping

“…Nature Communications 8: Article number: 15278 (2017); Published 5 May 2017; Updated 30 March 2018 The originally published version of this Article contained…”
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Multi-cycle signal-amplified colorimetric detection of tobramycin based on dual-strand displacement and three-way DNA junction by Ou, Ying, Jin, Xin, Fang, Jingwen, Tian, Yaping, Zhou, Nandi

“…•Colorimetric assay of tobramycin was developed via multiple signal amplification.•Isothermal amplification and DNA junction-based loop amplification were…”
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Salvianolic acid A inhibits the growth of diffuse large B-cell lymphoma through MAPK pathways by Li, Shuting, Fang, Jingwen, Si, Ting, Lu, Ying, Jiang, Lei

“…•Salvianolic acid A reduced the viability of DLBCL cells in vitro.•Salvianolic acid A inhibited DLBCL tumor growth in vivo.•Salvianolic acid A regulated MAPK…”
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miR-146a promotes M2 macrophage polarization and accelerates diabetic wound healing by inhibiting the TLR4/NF-κB axis by Peng, Xuefeng, He, Fang, Mao, Yanling, Lin, Yihui, Fang, Jingwen, Chen, Yangchun, Sun, Zhichun, Zhuo, Yafen, Jiang, Jianjia

“…We tried to unveil the clinical significance of miR-146a as a biomarker in M2 macrophage polarization in diabetic wound healing. Initially, we found reduced…”
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RNAkines are secreted messengers shaping health and disease by Li, Jing, Fang, Jingwen, Jiang, Xiaohong, Zhang, Yujing, Vidal-Puig, Antonio, Zhang, Chen-Yu

“…A new nomenclature ‘RNAkine’ is proposed to designate extracellular noncoding RNA in light of its tightly regulated secretion, signalling properties, and…”
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