Search Results - "Fang, Edward"

Effects of organizational learning on process technology and operations performance in mass customizers by Fang, Edward Aihua, Li, Xiaoyi, Lu, Jiajun

“…This study investigates the role of organizational learning and process technology in the implementation of mass customization based on 211 samples obtained…”
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Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial by Moran, Gregory J, Prof, Fang, Edward, MD, Corey, G Ralph, Prof, Das, Anita F, PhD, De Anda, Carisa, PharmD, Prokocimer, Philippe, Dr

“…Summary Background New antibiotics are needed to treat infections caused by drug-resistant bacteria. Tedizolid is a novel oxazolidinone antibacterial drug…”
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Analysis of the phase 3 ESTABLISH trials of tedizolid versus linezolid in acute bacterial skin and skin structure infections by Shorr, Andrew F, Lodise, Thomas P, Corey, G Ralph, De Anda, Carisa, Fang, Edward, Das, Anita F, Prokocimer, Philippe

“…Tedizolid, a novel oxazolidinone with activity against a wide range of Gram-positive pathogens, was evaluated in two noninferiority phase 3 acute bacterial…”
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Inflammatory mediators induced by amyloid-beta in the retina and RPE in vivo: implications for inflammasome activation in age-related macular degeneration by Liu, Ruozhou Tom, Gao, Jiangyuan, Cao, Sijia, Sandhu, Navroop, Cui, Jing Z, Chou, Chai Lin, Fang, Edward, Matsubara, Joanne A

“…Drusen are hallmarks of age-related macular degeneration (AMD). Amyloid-beta 1-40 (Aβ 1-40), a constituent of drusen, is known to stimulate inflammatory…”
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Absorption, distribution, metabolism, and excretion of the novel antibacterial prodrug tedizolid phosphate by Ong, Voon, Flanagan, Shawn, Fang, Edward, Dreskin, Howard J, Locke, Jeffrey B, Bartizal, Kenneth, Prokocimer, Philippe

“…Tedizolid phosphate is a novel antibacterial prodrug with potent activity against Gram-positive pathogens. In vitro and in vivo studies demonstrated that the…”
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The impact of new product & operations technological practices on organization structure by Fang, Edward Aihua, Wu, Qizhi, Miao, Chaowei, Xia, Jiansheng, Chen, Dezhi

“…This study chooses two product technological elements (customized design and modular design) and two operations technological elements (process automation and…”
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Efficacy, safety, tolerability and population pharmacokinetics of tedizolid, a novel antibiotic, in Latino patients with acute bacterial skin and skin structure infections by Ortiz-Covarrubias, Alejandro, Fang, Edward, Prokocimer, Philippe G., Flanagan, Shawn D., Zhu, Xu, Cabré-Márquez, Jose Francisco, Tanaka, Toshiaki, Passarell, Julie, Fiedler-Kelly, Jill, Nannini, Esteban C.

“…Acute bacterial skin and skin structure infections are caused mainly by Gram-positive bacteria which are often treated with intravenous vancomycin, daptomycin,…”
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Tedizolid Phosphate vs Linezolid for Treatment of Acute Bacterial Skin and Skin Structure Infections: The ESTABLISH-1 Randomized Trial by Prokocimer, Philippe, De Anda, Carisa, Fang, Edward, Mehra, Purvi, Das, Anita

“…IMPORTANCE Acute bacterial skin and skin structure infections (ABSSSIs), including cellulitis or erysipelas, major cutaneous abscesses, and wound infections,…”
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More work cooperation or relationship harmony in mass customization? The impacts of personalized design, modular design, and automated processes by Fang, Edward Aihua, Yang, Na

“…Mass customization (MC) is recognized as a new manufacturing paradigm for market competition, and several empirical studies have discussed elements of…”
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1702. Platelet Counts in Contezolid Complicated Skin and Soft Tissue Infection Phase 2 and Phase 3 Clinical Trials by Fang, Edward, Yang, Huahui, Yuan, Hong

“…Abstract Background Contezolid (CZD; MRX-I) is a novel oral (PO) oxazolidinone with potent activity against Gram-positive pathogens, including…”
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1700. Efficacy and Safety in Subjects with Renal Impairment in Contezolid and Contezolid Acefosamil Phase 2 and Phase 3 Skin Infection Clinical Trials by Fang, Edward, Yang, Huahui, Yuan, Hong

“…Abstract Background Contezolid (CZD; MRX-I) is a novel oral (PO) oxazolidinone with potent activity against Gram-positive pathogens, including…”
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1701. Pharmacokinetics in Subjects with Renal Impairment in a Contezolid Complicated Skin and Soft Tissue Infection Phase 3 Clinical Trial by Fang, Edward, Yang, Huahui, Yuan, Hong

“…Abstract Background Contezolid (CZD; MRX-I) is a novel oral (PO) oxazolidinone with potent activity against Gram-positive pathogens, including…”
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1699. Efficacy and Safety by BMI Category and Gender in Contezolid and Contezolid Acefosamil Phase 2 and Phase 3 Skin Infection Clinical Trials by Fang, Edward, Yang, Huahui, Yuan, Hong

“…Abstract Background Contezolid (CZD; MRX-I) is a novel oral (PO) oxazolidinone with potent activity against multidrug-resistant Gram-positive pathogens…”
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1118. Population Pharmacokinetics of Contezolid Acefosamil and Contezolid – Rationale for a Safe and Effective Loading Dose Regimen by Bulitta, Jürgen B, Hafkin, Barry, Fang, Edward

“…Abstract Background Contezolid (CZD) is a novel oral oxazolidnone with comparable activity and potentially improved safety compared to current oxazolidinones…”
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Platelet profile in patients with acute bacterial skin and skin structure infections receiving tedizolid or linezolid: findings from the Phase 3 ESTABLISH clinical trials by Lodise, Thomas P, Fang, Edward, Minassian, Sonia L, Prokocimer, Philippe G

“…Tedizolid, the active moiety of tedizolid phosphate, is a recently approved oxazolidinone antibacterial with activity against a wide range of Gram-positive…”
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Population pharmacokinetic rationale for intravenous contezolid acefosamil followed by oral contezolid dosage regimens by Bulitta, Jürgen B, Fang, Edward, Stryjewski, Martin E, Wang, Wen, Atiee, George J, Stark, Jeffrey G, Hafkin, Barry

“…Contezolid is a novel oxazolidinone antibiotic with a promising safety profile. Oral contezolid and its intravenous (IV) prodrug contezolid acefosamil (CZA)…”
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Clinical Response of Tedizolid versus Linezolid in Acute Bacterial Skin and Skin Structure Infections by Severity Measure Using a Pooled Analysis from Two Phase 3 Double-Blind Trials by Sandison, Taylor, De Anda, Carisa, Fang, Edward, Das, Anita F, Prokocimer, Philippe

“…Tedizolid phosphate is approved for the treatment of acute bacterial skin and skin structure infections (ABSSSI). In a pooled analysis of 1,333 ABSSSI patients…”
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Single- and Multiple-Dose Pharmacokinetics and Absolute Bioavailability of Tedizolid by Flanagan, Shawn, Fang, Edward, Muñoz, Kelly A., Minassian, Sonia L., Prokocimer, Philippe G.

“…Objectives Tedizolid phosphate is a novel antibacterial under investigation for the treatment of gram‐positive infections. This study was conducted to assess…”
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Effects of therapeutic and supratherapeutic doses of oral tedizolid phosphate on cardiac repolarisation in healthy volunteers: a randomised controlled study by Flanagan, Shawn, Litwin, Jeffrey, Fang, Edward, Prokocimer, Philippe

“…Highlights • Drugs associated with QT prolongation include several classes of commonly used antibacterial agents. • Guidelines recommend clinical…”
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916: Neurologic and Ophthalmologic Safety Results with 10 Day Dosing of Tedizolid Phosphate by Fang, Edward, Muñoz, Kelly Ann, Prokocimer, Philippe

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