Search Results - "Fang, Chaodong"
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Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy
Published in Nature (London) (12-04-2012)“…Pregnant corin- or ANP-deficient mice have impaired trophoblast invasion and uterine spiral artery remodelling, and patients with pre-eclampsia have lower…”
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Corin Mutation R539C from Hypertensive Patients Impairs Zymogen Activation and Generates an Inactive Alternative Ectodomain Fragment
Published in The Journal of biological chemistry (15-03-2013)“…Corin is a cardiac transmembrane serine protease that regulates blood pressure by activating natriuretic peptides. Corin variants have been associated with…”
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Reduced urinary corin levels in patients with chronic kidney disease
Published in Clinical science (1979) (01-06-2013)“…Corin is a cardiac protease that regulates BP (blood pressure) by activating natriuretic peptides. Recent animal studies identified corin expression in the…”
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Reduced serum corin levels in patients with osteoporosis
Published in Clinica chimica acta (15-11-2013)“…Corin is a cardiac protease that activates the natriuretic peptides. Corin is also expressed in chondrocytes and bone marrow-derived mesenchymal stem cells…”
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Molecular studies of novel corin mutations in patients with hypertension and heart failure
Published in The FASEB journal (01-04-2011)“…Corin is a membrane serine protease that activates atrial natriuretic peptide (ANP), a cardiac hormone important in regulating blood pressure and salt‐water…”
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Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy
Published in Nature (London) (12-04-2012)“…In pregnancy, trophoblast invasion and uterine spiral artery remodelling are important for lowering maternal vascular resistance and increasing uteroplacental…”
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Journal Article