Search Results - "Faneca, H"

Intranasal Administration of Novel Chitosan Nanoparticle/DNA Complexes Induces Antibody Response to Hepatitis B Surface Antigen in Mice by Lebre, F, Borchard, G, Faneca, H, Pedroso de Lima, M. C, Borges, O

“…The generation of strong pathogen-specific immune responses at mucosal surfaces where hepatitis B virus (HBV) transmission can occur is still a major…”
Get full text

In Situ Forming Chitosan Hydrogels Prepared via Ionic/Covalent Co-Cross-Linking by Moura, M. José, Faneca, H, Lima, M. Pedroso, Gil, M. Helena, Figueiredo, M. Margarida

“…In situ forming chitosan hydrogels have been prepared via coupled ionic and covalent cross-linking. Thus, different amounts of genipin (0.05, 0.10, 0.15, and…”
Get full text

832: MicroRNA-139-5p: A tool for metastasis and chemotherapeutic resistance control in pancreatic adenocarcinoma by Passadouro, M, Nóbrega, C, Almeida, L, Pedroso de Lima, M, Faneca, H

Get full text

1028 A Novel Lipoplex Formulation for Targeted Cancer Gene Therapy by Alves Farinha, D. Pereira, de Lima, M. Pedroso, Faneca, H

Get full text

Synergistic antitumoral effect of vinblastine and HSV-Tk/GCV gene therapy mediated by albumin-associated cationic liposomes by Faneca, H., Faustino, A., Pedroso de Lima, M.C.

“…Despite recent advances in conventional therapeutic approaches for cancer, the frequently observed acquired drug resistance and toxic side effects have limited…”
Get full text

Vanadium compounds as therapeutic agents: Some chemical and biochemical studies by Faneca, H., Figueiredo, V.A., Tomaz, Isabel, Gonçalves, Gisela, Avecilla, Fernando, Pedroso de Lima, M.C., Geraldes, Carlos F.G.C., Pessoa, João Costa, Castro, M. Margarida C.A.

“…The behaviour of three vanadium(V) systems, namely the pyridinone (V V-dmpp), the salicylaldehyde (V V-salDPA) and the pyrimidinone (V V-MHCPE) complexes, is…”
Get full text

Evaluation of lipid-based reagents to mediate intracellular gene delivery by Faneca, H, Simões, S, Pedroso de Lima, M.C

“…We characterized different cationic lipid-based gene delivery systems consisting of both liposomes and nonliposomal structures, in terms of their in vitro…”
Get full text

Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system by Faneca, H., Cabrita, A.S., Simões, S., Pedroso de Lima, M.C.

“…In the present work, we used a novel albumin-associated lipoplex formulation, containing the cationic lipid 1-palmitoyl-2-oleoyl-…”
Get full text

Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response by Neves, S, Faneca, H, Bertin, S, Konopka, K, Düzgüneş, N, Pierrefite-Carle, V, Simões, S, Pedroso de Lima, M C

“…Suicide gene therapy has been used for the treatment of a variety of cancers. We reported previously the in vitro efficacy of the Herpes Simplex Virus…”
Get full text

Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum by Faneca, H., Simões, S., Pedroso de Lima, M. C.

“…Background The successful application of gene therapy depends on the availability of carriers to efficiently deliver genetic material into target cells. Such…”
Get full text

274 Development of folate-lipid-based systems for tumour-targeted gene delivery by Duarte, S, Faneca, H, Pedroso de Lima, M.C

Get full text

A Combined Antitumor Strategy Mediated by a New Targeted Nanosystem to Hepatocellular Carcinoma by Farinha, Dina, Migawa, Michael, Sarmento-Ribeiro, Ana, Faneca, Henrique

“…Hepatocellular carcinoma (HCC) is one of the main causes of cancer-related death. Sorafenib, which is the first-line therapy for this disease, is associated…”
Get full text

MicroRNA modulation combined with sunitinib as a novel therapeutic strategy for pancreatic cancer by Passadouro, Marta, Pedroso de Lima, Maria C, Faneca, Henrique

“…Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and mortal cancer, characterized by a set of known mutations, invasive features, and aberrant…”
Get full text

Cationic lipid–DNA complexes in gene delivery: from biophysics to biological applications by Pedroso de Lima, Maria C, Simões, Sérgio, Pires, Pedro, Faneca, Henrique, Düzgüneş, Nejat

“…Great expectations from the application of gene therapy approaches to human disease have been impaired by the unsatisfactory clinical progress observed. Among…”
Get full text

Increased gene delivery efficiency and specificity of a lipid-based nanosystem incorporating a glycolipid by Magalhães, Mariana, Farinha, Dina, Pedroso de Lima, Maria Conceição, Faneca, Henrique

“…Hepatocellular carcinoma (HCC) is the third most common cause of death related to cancer diseases worldwide. The current treatment options have many…”
Get full text