Search Results - "Fandl, James"

VEGF-Trap: A VEGF Blocker with Potent Antitumor Effects by Holash, Jocelyn, Davis, Sam, Papadopoulos, Nick, Croll, Susan D., Ho, Lillian, Russell, Michelle, Boland, Patricia, Leidich, Ray, Hylton, Donna, Burova, Elena, Ioffe, Ella, Huang, Tammy, Radziejewski, Czeslaw, Bailey, Kevin, Fandl, James P., Daly, Tom, Wiegand, Stanley J., Yancopoulos, George D., Rudge, John S.

“…Vascular endothelial growth factor (VEGF) plays a critical role during normal embryonic angiogenesis and also in the pathological angiogenesis that occurs in a…”
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Angiopoietin-2 Functions as an Autocrine Protective Factor in Stressed Endothelial Cells by Daly, Christopher, Pasnikowski, Elizabeth, Burova, Elena, Wong, Vivian, Aldrich, Thomas H., Griffiths, Jennifer, Ioffe, Ella, Daly, Thomas J., Fandl, James P., Papadopoulos, Nick, McDonald, Donald M., Thurston, Gavin, Yancopoulos, George D., Rudge, John S.

“…Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of…”
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Cytokine traps: multi-component, high-affinity blockers of cytokine action by Stahl, Neil, Economides, Aris N, Carpenter, Laura Rocco, Rudge, John S, Wong, Vivien, Koehler-Stec, Ellen M, Hartnett, Christopher, Pyles, Erica A, Xu, Xiaobing, Daly, Thomas J, Young, Michael R, Fandl, James P, Lee, Frank, Carver, Scott, McNay, Jennifer, Bailey, Kevin, Ramakanth, Swayampakula, Hutabarat, Renta, Huang, Tammy T, Radziejewski, Czeslaw, Yancopoulos, George D

“…Cytokines can initiate and perpetuate human diseases, and are among the best-validated of therapeutic targets. Cytokines can be blocked by the use of soluble…”
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In Vivo Somatic Cell Gene Transfer of an Engineered Noggin Mutein Prevents BMP4-Induced Heterotopic Ossification by Glaser, David L, Economides, Aris N, Wang, Lili, Liu, Xia, Kimble, Robert D, Fandl, James P, Wilson, James M, Stahl, Neil, Kaplan, Frederick S, Shore, Eileen M

“…BackgroundThe formation of the skeleton requires inductive signals that are balanced with their antagonists in a highly regulated negative feedback system…”
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A BDNF autocrine loop in adult sensory neurons prevents cell death by Acheson, Ann, Conover, Joanne C, Fandl, James P, DeChiara, Thomas M, Russell, Michelle, Thadani, Anu, Squinto, Stephen P, Yancopoulos, George D, Lindsay, Ronald M

“…During the initial phase of their development, sensory neurons of the dorsal root ganglion (DRG) require target-derived trophic support for their survival, but…”
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Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells by Ip, Nancy Y, Stitt, Trevor N, Tapley, Peter, Klein, Rudiger, Glass, David J, Fandl, James, Greene, Lloyd A, Barbacid, Mariano, Yancopoulos, George D

“…We have exploited a battery of approaches to address several controversies that have accompanied the expansion of the nerve growth factor (NGF) family of…”
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1H, 15N, and 13C resonance assignments of low molecular weight human cytoplasmic protein tyrosine phosphatase-A (HCPTP-A) by Rastogi, Vinit K, Diven, Conrad F, Seabrook, Genevieve M, Genbauffe, Frank S, Bechard, Randy T, Fandl, James P, Peters, Kevin G

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Letter to the Editor: 1H, 15N, and 13C resonance assignments of low molecular weight human cytoplasmic protein tyrosine phosphatase-A (HCPTP-A) by Rastogi, Vinit K, Diven, Conrad F, Seabrook, Genevieve M, Genbauffe, Frank S, Bechard, Randy T, Fandl, James P, Peters, Kevin G

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Biochemical Evidence for the secY24 Defect in Escherichia coli Protein Translocation and Its Suppression by Soluble Cytoplasmic Factors by Fandl, James P., Tai, Phang C.

“…The secY (prlA) gene product is an integral membrane protein that has been identified genetically as one of the central components of the Escherichia coli…”
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SecA Suppresses the Temperature-Sensitive SecY24 Defect in Protein Translocation in Escherichia coli Membrane Vesicles by Fandl, James P., Cabelli, Robert, Oliver, Donald, Tai, Phang C.

“…Genetic analysis of protein secretion in Escherichia coli has identified secY/prlA and secA as components of the secretory apparatus. We have examined the…”
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On protein translocation across bacterial cytoplasmic membranes by TAI, P. C, JIANPING LIAN, NIAN-JUN YU, FANDL, J, HAODA XU, VIDUGIRIENE, J

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