Search Results - "Fancellu, R"

Inventory of Non-Ataxia Signs (INAS): Validation of a New Clinical Assessment Instrument by Jacobi, H., Rakowicz, M., Rola, R., Fancellu, R., Mariotti, C., Charles, P., Dürr, A., Küper, M., Timmann, D., Linnemann, C., Schöls, L., Kaut, O., Schaub, C., Filla, A., Baliko, L., Melegh, B., Kang, J.-S., Giunti, P., van de Warrenburg, B. P. C., Fimmers, R., Klockgether, T.

“…Although ataxia is by definition the prominent symptom of ataxia disorders, there are various neurological signs that may accompany ataxia in affected…”
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The natural history of spinocerebellar ataxia type 1, 2, 3, and 6 A 2-year follow-up study by JACOBI, H, BAUER, P, SCHÖLS, L, RAKOWICZ, M, ROLA, R, ZDZIENICKA, E, SCHMITZ-HUBSCH, T, FANCELLU, R, MARIOTTI, C, TOMASELLO, C, BALIKO, L, MELEGH, B, GIUNTI, P, FILLA, A, RINALDI, C, VAN DE WARRENBURG, B. P, VERSTAPPEN, C. C. P, SZYMANSKI, S, BERCIANO, J, INFANTE, J, TIMMANN, D, BOESCH, S, HERING, S, LABRUM, R, DEPONDT, C, PANDOLFO, M, KANG, J.-S, RATZKA, S, SCHULZ, J, TEZENAS DU MONTCEL, S, KLOCKGETHER, T, SWEENEY, M. G, CHARLES, P, DÜRR, A, MARELLI, C, GLOBAS, C, LINNEMANN, C

“…To obtain quantitative data on the progression of the most common spinocerebellar ataxias (SCAs) and identify factors that influence their progression, we…”
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Responsiveness of different rating instruments in spinocerebellar ataxia patients by SCHMITZ-HÜBSCH, T, FIMMERS, R, FILLA, A, SALVATORE, E, INFANTE, J, GIUNTI, P, LABRUM, R, KREMER, B, VAN DE WARRENBURG, B. P. C, BALIKO, L, MELEGH, B, DEPONDT, C, RAKOWICZ, M, SCHULZ, J, DU MONTCEL, S. Tezenas, KLOCKGETHER, T, ROLA, R, ZDZIENICKA, E, FANCELLU, R, MARIOTTI, C, LINNEMANN, C, SCHÖLS, L, TIMMANN, D

“…To determine the longitudinal metric properties of recently developed clinical assessment tools in spinocerebellar ataxia (SCA). A subset of 171 patients from…”
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Spinocerebellar ataxia types 1, 2, 3, and 6 : Disease severity and nonataxia symptoms by SCHMITZ-HÜBSCH, T, COUDERT, M, RIBAI, P, SZYMANSKI, S, INFANTE, J, VAN DE WARRENBURG, B. P. C, DÜRR, A, TIMMANN, D, BOESCH, S, FANCELLU, R, ROLA, R, DEPONDT, C, BAUER, P, SCHÖLS, L, ZDIENICKA, E, KANG, J.-S, DÖHLINGER, S, KREMER, B, STEPHENSON, D. A, MELEGH, B, PANDOLFO, M, DI DONATO, S, TEZENAS DU MONTCEL, S, GIUNTI, P, KLOCKGETHER, T, GLOBAS, C, BALIKO, L, FILLA, A, MARIOTTI, C, RAKOWICZ, M, CHARLES, P

“…To identify factors that determine disease severity and clinical phenotype of the most common spinocerebellar ataxias (SCAs), we studied 526 patients with…”
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Can MR imaging diagnose adult-onset Alexander disease? by Farina, L, Pareyson, D, Minati, L, Ceccherini, I, Chiapparini, L, Romano, S, Gambaro, P, Fancellu, R, Savoiardo, M

“…In recent years, the discovery that mutations in the glial fibrillary acidic protein gene (GFAP) were responsible for Alexander disease (AD) brought…”
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SCA Functional Index : A useful compound performance measure for spinocerebellar ataxia by SCHMITZ-HÜBSCH, T, GIUNTI, P, VAN DE WARRENBURG, B. P. C, TIMMANN, D, FANCELLU, R, FROLA, R, DEPONDT, C, SCHÖLS, L, ZDZIENICKA, E, KANG, J.-S, DOHLINGER, S, KREMER, B, STEPHENSON, D. A, MELEGH, B, FILLA, A, KLOCKGETHER, T, GLOBAS, C, BALIKO, L, SACCA, F, MARIOTTI, C, RAKOWICZ, M, SZYMANSKI, S, INFANTE, J

“…To evaluate the usefulness of functional measures in patients with spinocerebellar ataxia (SCA). We assessed three functional measures-8 m walking time (8MW),…”
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Neuroprotective effect of rasagiline in a rodent model of Parkinson's disease by Blandini, F., Armentero, M.T., Fancellu, R., Blaugrund, E., Nappi, G.

“…Sprague–Dawley rats received a unilateral injection of 6-hydroxydopamine (6-OHDA) into the striatum and were treated daily for 6 weeks with increasing doses of…”
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Cognitive and affective status in mild hypothyroidism and interactions with l-thyroxine treatment by Bono, G., Fancellu, R., Blandini, F., Santoro, G., Mauri, M.

“…Objectives – While clinical hypothyroidism is associated with frank neuropsychological and affective alterations and is considered one of the causes of…”
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Diffusion Tensor Imaging of Spinocerebellar Ataxias Types 1 and 2 by Mandelli, M.L, De Simone, T, Minati, L, Bruzzone, M.G, Mariotti, C, Fancellu, R, Savoiardo, M, Grisoli, M

“…Structural MR imaging does not enable reliable differentiation of spinocerebellar ataxia (SCA) types 1 and 2 (SCA1 and SCA2), and imaging may be normal during…”
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Spinocerebellar ataxia type 17 (SCA17) : Oculomotor phenotype and clinical characterization of 15 Italian patients by MARIOTTI, Caterina, ALPINI, Dario, TARONI, Franco, GELLERA, Cinzia, DI DONATO, Stefano, FANCELLU, Roberto, SOLIVERI, Paola, GRISOLI, Marina, RAVAGLIA, Sabrina, LOVATI, Carlo, FETONI, Vincenza, GIACCONE, Giorgio, CASTUCCI, Alessia

“…SCA17 is a rare type of autosomal dominant spinocerebellar ataxia caused by a CAG/CAA expansion in the gene encoding the TATA-binding protein (TBP). We…”
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Peripheral levels of BDNF and NGF in primary headaches by Blandini, F, Rinaldi, L, Tassorelli, C, Sances, G, Motta, M, Samuele, A, Fancellu, R, Nappi, G, Leon, A

“…Neurotrophins, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), have been implicated in the generation and modulation of pain…”
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Plasma homocysteine and l-DOPA Metabolism in patients with Parkinson Disease by BLANDINI, Fabio, FANCELLU, Roberto, MARTIGNONI, Emilia, MANGIAGALLI, Anna, NAPPI, Giuseppe, SAMUEL, Alberta, PACHETTI, Claudio

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Predictive genetic tests in neurodegenerative disorders: a methodological approach integrating psychological counseling for at-risk individuals and referring clinicians by Mariotti, C, Ferruta, A, Gellera, C, Nespolo, C, Fancellu, R, Genitrini, S, Di Bella, D, Panzeri, M, Nanetti, L, Tomasello, C, Taroni, F, Foresti, G, Astori, S

“…The identification of the molecular basis of numerous hereditary neurological disorders allowed the feasibility of predictive genetic tests for at-risk family…”
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Modifications of apoptosis-related protein levels in lymphocytes of patients with Parkinson's disease. The effect of dopaminergic treatment by Blandini, F, Cosentino, M, Mangiagalli, A, Marino, F, Samuele, A, Rasini, E, Fancellu, R, Tassorelli, C, Pacchetti, C, Martignoni, E, Riboldazzi, G, Calandrella, D, Lecchini, S, Frigo, G, Nappi, G

“…In this study, we investigated whether changes in the regulatory mechanisms of apoptosis and oxidative stress may be detected, peripherally, in patients with…”
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Peripheral markers of apoptosis in Parkinson's disease: the effect of dopaminergic drugs by Blandini, F, Mangiagalli, A, Cosentino, M, Marino, F, Samuele, A, Rasini, E, Fancellu, R, Martignoni, E, Riboldazzi, G, Calandrella, D, Frigo, G M, Nappi, G

“…In this study, we measured the lymphocyte levels of proteins involved in apoptosis regulation, such as Bcl-2, the peripheral benzodiazepine receptor (PBR),…”
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Selective lesion of the substantia nigra pars reticulata reduces the cortical Fos expression induced by stimulation of striatal D1-like receptors, in the rat by BLANDINI, F, ARMENTERO, M. T, TASSORELLI, C, GRECO, R, FANCELLU, R, BRAMANTI, P, NAPPI, G, MARTIGNONI, E

“…We investigated the effects of a selective lesion of the substantia nigra pars reticulata (SNr), obtained by stereotaxic injection of ibotenic acid, on the…”
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Can MR Imaging Diagnose Adult-Onset Alexander Disease? by Farina, L, Pareyson, D, Minati, L, Ceccherini, I, Chiapparini, L, Romano, S, Gambaro, P, Fancellu, R, Savoiardo, M

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Neuroprotective effects mediated by dopamine receptor agonists against malonate-induced lesion in the rat striatum by Fancellu, R, Armentero, M-T, Nappi, G, Blandini, F

“…In rats, intrastriatal injection of malonate, a reversible inhibitor of the mitochondrial enzyme succinate dehydrogenase, induces a lesion similar to that…”
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Modifications of plasma and platelet levels of L-DOPA and its direct metabolites during treatment with tolcapone or entacapone in patients with Parkinson's disease by BLANDINI, F, NAPPI, G, FANCELLU, R, MANGIAGALLI, A, SAMUELE, A, RIBOLDAZZI, G, CALANDRELLA, D, PACCHETTI, C, BONO, G, MARTIGNON, E

“…We compared--retrospectively--the effects of a 3-month therapy with catechol- O-methyltransferase (COMT) inhibitors tolcapone (100 mg, t.i.d.) and entacapone…”
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Blockade of subthalamic glutamatergic activity corrects changes in neuronal metabolism and motor behavior in rats with nigrostriatal lesions by Blandini, F, Greenamyre, J T, Fancellu, R, Nappi, G

“…We infused--for four weeks--a selective antagonist of the NMDA receptor, MK-801, into the subthalamic nucleus of rats bearing an evolving nigrostriatal lesion…”
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