Search Results - "Fan, Yi Chiao"
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Advances in nucleophilic phosphine catalysis of alkenes, allenes, alkynes, and MBHADs
Published in Chemical communications (Cambridge, England) (25-12-2013)“…In nucleophilic phosphine catalysis, tertiary phosphines undergo conjugate additions to activated carbon-carbon multiple bonds to form β-phosphonium enolates,…”
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Diversity-oriented synthesis based on the DPPP-catalyzed mixed double-Michael reactions of electron-deficient acetylenes and β-amino alcohols
Published in Molecules (Basel, Switzerland) (05-05-2011)“…In this study, we prepared oxizolidines through 1,3-bis(diphenylphosphino)-propane (DPPP)-catalyzed mixed double-Michael reactions of β-amino alcohols with…”
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Phosphine Organocatalysis
Published in Chemical reviews (24-10-2018)“…The hallmark of nucleophilic phosphine catalysis is the initial nucleophilic addition of a phosphine to an electrophilic starting material, producing a…”
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Synthesis of Functionalized Alkylidene Indanes and Indanones through Tandem Phosphine–Palladium Catalysis
Published in Organic letters (01-05-2015)“…Densely functionalized alkylidene indanes and indanones can be prepared efficiently in one pot, in high yields with good stereoselectivities (in some cases…”
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Phosphine/Palladium-Catalyzed Syntheses of Alkylidene Phthalans, 3-Deoxyisoochracinic Acid, Isoochracinic Acid, and Isoochracinol
Published in Organic letters (06-07-2012)“…In this study we used sequential catalysisPPh3-catalyzed nucleophilic addition followed by Pd(0)-catalyzed Heck cyclizationto construct complex…”
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Hydroxyproline-Derived Pseudoenantiomeric [2.2.1] Bicyclic Phosphines: Asymmetric Synthesis of (+)- and (−)-Pyrrolines
Published in Journal of the American Chemical Society (27-08-2014)“…We have prepared two new diastereoisomeric 2-aza-5-phosphabicyclo[2.2.1]heptanes from naturally occurring trans-4-hydroxy-l-proline in six chemical…”
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Catalytic Enantioselective Synthesis of Guvacine Derivatives through [4 + 2] Annulations of Imines with α‑Methylallenoates
Published in Organic letters (05-10-2018)“…P-Chiral [2.2.1] bicyclic phosphines (HypPhos catalysts) have been applied to reactions between α-alkylallenoates and imines, producing guvacine derivatives…”
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Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival
Published in ACS chemical biology (17-04-2015)“…Platelet-activating factor acetylhydrolases (PAFAHs) 1b2 and 1b3 are poorly characterized serine hydrolases that form a complex with a noncatalytic protein…”
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Diversity-Oriented Synthesis Based on the DPPP-Catalyzed Mixed Double-Michael Reactions of Electron-Deficient Acetylenes and [beta]-Amino Alcohols
Published in Molecules (Basel, Switzerland) (01-05-2011)“…In this study, we prepared oxizolidines through 1,3-bis(diphenylphosphino)-propane (DPPP)-catalyzed mixed double-Michael reactions of b-amino alcohols with…”
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Journal Article -
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Tandem Phosphine-Palladium Catalysis and Total Syntheses of Natural Products
Published 01-01-2015“…In Chapter 1, tertiary phosphines undergo conjugate additions to activated carbon–carbon multiple bonds to form β-phosphonium enolates, β-phosphonium…”
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Dissertation