Search Results - "Fan, Xiaoying"

Single-cell RNA-seq transcriptome analysis of linear and circular RNAs in mouse preimplantation embryos by Fan, Xiaoying, Zhang, Xiannian, Wu, Xinglong, Guo, Hongshan, Hu, Yuqiong, Tang, Fuchou, Huang, Yanyi

“…Circular RNAs (circRNAs) are a new class of non-polyadenylated non-coding RNAs that may play important roles in many biological processes. Here we develop a…”
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A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex by Zhong, Suijuan, Zhang, Shu, Fan, Xiaoying, Wu, Qian, Yan, Liying, Dong, Ji, Zhang, Haofeng, Li, Long, Sun, Le, Pan, Na, Xu, Xiaohui, Tang, Fuchou, Zhang, Jun, Qiao, Jie, Wang, Xiaoqun

“…WebAnalysis of gene expression at single-cell resolution in the developing prefrontal cortex of the human embryo reveals a diversity of cell types, elucidates…”
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Single-cell RNA-seq analysis reveals the progression of human osteoarthritis by Ji, Quanbo, Zheng, Yuxuan, Zhang, Guoqiang, Hu, Yuqiong, Fan, Xiaoying, Hou, Yu, Wen, Lu, Li, Li, Xu, Yameng, Wang, Yan, Tang, Fuchou

“…Understanding the molecular mechanisms underlying human cartilage degeneration and regeneration is helpful for improving therapeutic strategies for treating…”
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Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart by Cui, Yueli, Zheng, Yuxuan, Liu, Xixi, Yan, Liying, Fan, Xiaoying, Yong, Jun, Hu, Yuqiong, Dong, Ji, Li, Qingqing, Wu, Xinglong, Gao, Shuai, Li, Jingyun, Wen, Lu, Qiao, Jie, Tang, Fuchou

“…The heart is the central organ of the circulatory system, and its proper development is vital for maintaining human life. Here, we used single-cell RNA…”
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Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta by Liu, Yawei, Fan, Xiaoying, Wang, Rui, Lu, Xiaoyin, Dang, Yan-Li, Wang, Huiying, Lin, Hai-Yan, Zhu, Cheng, Ge, Hao, Cross, James C., Wang, Hongmei

“…The placenta is crucial for a successful pregnancy and the health of both the fetus and the pregnant woman. However, how the human trophoblast lineage is…”
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Review of Metabolomics-Based Biomarker Research for Parkinson’s Disease by Li, Xin, Fan, Xiaoying, Yang, Hongtian, Liu, Yufeng

“…Parkinson’s disease (PD), as the second most common neurodegenerative disease, is seriously affecting the life quality of the elderly. However, there is still…”
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SMOOTH-seq: single-cell genome sequencing of human cells on a third-generation sequencing platform by Fan, Xiaoying, Yang, Cheng, Li, Wen, Bai, Xiuzhen, Zhou, Xin, Xie, Haoling, Wen, Lu, Tang, Fuchou

“…There is no effective way to detect structure variations (SVs) and extra-chromosomal circular DNAs (ecDNAs) at single-cell whole-genome level. Here, we develop…”
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Decoding the development of the human hippocampus by Zhong, Suijuan, Ding, Wenyu, Sun, Le, Lu, Yufeng, Dong, Hao, Fan, Xiaoying, Liu, Zeyuan, Chen, Ruiguo, Zhang, Shu, Ma, Qiang, Tang, Fuchou, Wu, Qian, Wang, Xiaoqun

“…The hippocampus is an important part of the limbic system in the human brain that has essential roles in spatial navigation and the consolidation of…”
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DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells by Guo, Hongshan, Hu, Boqiang, Yan, Liying, Yong, Jun, Wu, Yan, Gao, Yun, Guo, Fan, Hou, Yu, Fan, Xiaoying, Dong, Ji, Wang, Xiaoye, Zhu, Xiaohui, Yan, Jie, Wei, Yuan, Jin, Hongyan, Zhang, Wenxin, Wen, Lu, Tang, Fuchou, Qiao, Jie

“…Chromatin remodeling is important for the epigenetic reprogramming of human primordial germ cells. However, the comprehensive chromatin state has not yet been…”
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Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis by Fan, Xiaoying, Dong, Ji, Zhong, Suijuan, Wei, Yuan, Wu, Qian, Yan, Liying, Yong, Jun, Sun, Le, Wang, Xiaoye, Zhao, Yangyu, Wang, Wei, Yan, Jie, Wang, Xiaoqun, Qiao, Jie, Tang, Fuchou

“…The cellular complexity of human brain development has been intensively investigated, although a regional characterization of the entire human cerebral cortex…”
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Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions by Li, Li, Dong, Ji, Yan, Liying, Yong, Jun, Liu, Xixi, Hu, Yuqiong, Fan, Xiaoying, Wu, Xinglong, Guo, Hongshan, Wang, Xiaoye, Zhu, Xiaohui, Li, Rong, Yan, Jie, Wei, Yuan, Zhao, Yangyu, Wang, Wei, Ren, Yixin, Yuan, Peng, Yan, Zhiqiang, Hu, Boqiang, Guo, Fan, Wen, Lu, Tang, Fuchou, Qiao, Jie

“…Human fetal germ cells (FGCs) are precursors to sperm and eggs and are crucial for maintenance of the species. However, the developmental trajectories and…”
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The DNA methylation landscape of human early embryos by Guo, Hongshan, Zhu, Ping, Yan, Liying, Li, Rong, Hu, Boqiang, Lian, Ying, Yan, Jie, Ren, Xiulian, Lin, Shengli, Li, Junsheng, Jin, Xiaohu, Shi, Xiaodan, Liu, Ping, Wang, Xiaoye, Wang, Wei, Wei, Yuan, Li, Xianlong, Guo, Fan, Wu, Xinglong, Fan, Xiaoying, Yong, Jun, Wen, Lu, Xie, Sunney X., Tang, Fuchou, Qiao, Jie

“…Base-resolution maps of DNA methylation in human gametes and early embryos offer novel insights into human methylation dynamics and the functional relationship…”
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Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells by Wu, Yuxuan, Zhou, Hai, Fan, Xiaoying, Zhang, Ying, Zhang, Man, Wang, Yinghua, Xie, Zhenfei, Bai, Meizhu, Yin, Qi, Liang, Dan, Tang, Wei, Liao, Jiaoyang, Zhou, Chikai, Liu, Wujuan, Zhu, Ping, Guo, Hongshan, Pan, Hong, Wu, Chunlian, Shi, Huijuan, Wu, Ligang, Tang, Fuchou, Li, Jinsong

“…Spermatogonial stem cells （SSCs） can produce numerous male gametes after transplantation into recipient testes, presenting a valuable approach for gene therapy…”
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Single-cell multi-omics sequencing and its applications in studying the nervous system by Wang, Chaoyang, Fan, Xiaoying

“…Single-cell sequencing has become one of the most powerful and popular techniques in dissecting molecular heterogeneity and modeling the cellular architecture…”
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Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses by Hou, Siyuan, Li, Zongcheng, Zheng, Xiaona, Gao, Yun, Dong, Ji, Ni, Yanli, Wang, Xiaobo, Li, Yunqiao, Ding, Xiaochen, Chang, Zhilin, Li, Shuaili, Hu, Yuqiong, Fan, Xiaoying, Hou, Yu, Wen, Lu, Liu, Bing, Tang, Fuchou, Lan, Yu

“…Hematopoietic stem cells (HSCs) in adults are believed to be born from hemogenic endothelial cells (HECs) in mid-gestational embryos. Due to the rare and…”
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Categorizing Extrachromosomal Circular DNA as Biomarkers in Serum of Cancer by Deng, Enze, Fan, Xiaoying

“…Extrachromosomal circular DNA (eccDNA), a double-stranded circular DNA molecule found in multiple organisms, has garnered an increasing amount of attention in…”
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Single-cell RNA-seq analysis of mouse preimplantation embryos by third-generation sequencing by Fan, Xiaoying, Tang, Dong, Liao, Yuhan, Li, Pidong, Zhang, Yu, Wang, Minxia, Liang, Fan, Wang, Xiao, Gao, Yun, Wen, Lu, Wang, Depeng, Wang, Yang, Tang, Fuchou

“…The development of next generation sequencing (NGS) platform-based single-cell RNA sequencing (scRNA-seq) techniques has tremendously changed biological…”
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Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells by Chang, Lei, Li, Mengfan, Shao, Shipeng, Li, Chen, Ai, Shanshan, Xue, Boxin, Hou, Yingping, Zhang, Yiwen, Li, Ruifeng, Fan, Xiaoying, He, Aibin, Li, Cheng, Sun, Yujie

“…The eukaryotic genome is folded into higher-order conformation accompanied with constrained dynamics for coordinated genome functions. However, the molecular…”
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Effect of breathing phase number on the 4D robust optimization for pancreatic cancer intensity modulated proton therapy by Fan, Xiaoying, Wang, Shuting, Li, Weijie, Li, Tengxiang, Yin, Yong, Dai, Tianyuan

“…Respiratory movement, as one of the main challenges in proton therapy for pancreatic cancer patients, could not only lead to harm to normal tissues but also…”
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Tracing the expression of circular RNAs in human pre-implantation embryos by Dang, Yujiao, Yan, Liying, Hu, Boqiang, Fan, Xiaoying, Ren, Yixin, Li, Rong, Lian, Ying, Yan, Jie, Li, Qingqing, Zhang, Yan, Li, Min, Ren, Xiulian, Huang, Jin, Wu, Yuqi, Liu, Ping, Wen, Lu, Zhang, Chen, Huang, Yanyi, Tang, Fuchou, Qiao, Jie

“…PolyA- RNAs have not been widely analyzed in human pre-implantation embryos due to the scarcity of materials. In particular, circular RNA (circRNA), a novel…”
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