Search Results - "Fan, Weizheng"

Photodegradable and size-tunable single-chain nanoparticles prepared from a single main-chain coumarin-containing polymer precursor by Fan, Weizheng, Tong, Xia, Yan, Qiang, Fu, Shangyi, Zhao, Yue

“…A polyester bearing coumarin moieties in the main chain was used to prepare photodegradable single-chain nanoparticles (SCNPs) of variable sizes. While the…”
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Photoresponsive Coumarin Polyesters That Exhibit Cross-Linking and Chain Scission Properties by Maddipatla, Murthy V. S. N, Wehrung, Daniel, Tang, Chuan, Fan, Weizheng, Oyewumi, Moses O, Miyoshi, Toshikazu, Joy, Abraham

“…The synthesis and properties of a new class of photoresponsive coumarin polyesters are described. Incorporation of the coumarin chromophore in the polymer…”
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Ruthenium-Catalyzed Enantioselective Hydrogenation of Aryl-Pyridyl Ketones by Tao, Xiaoming, Li, Wanfang, Ma, Xin, Li, Xiaoming, Fan, Weizheng, Xie, Xiaomin, Ayad, Tahar, Ratovelomanana-Vidal, Virginie, Zhang, Zhaoguo

“…Various substituted aryl-pyridyl ketones were hydrogenated in the presence of Ru-XylSunPhos-Daipen bifunctional catalytic system with enantiomeric excesses up…”
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Enantioselective Hydrogenation of β‑Ketophosphonates with Chiral Ru(II) Catalysts by Tao, Xiaoming, Li, Wanfang, Ma, Xin, Li, Xiaoming, Fan, Weizheng, Zhu, Lvfeng, Xie, Xiaomin, Zhang, Zhaoguo

“…Highly effective asymmetric hydrogenation of β-ketophosphonates in the presence of Ru–(S)-SunPhos as catalyst was realized; good to excellent…”
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Direct Asymmetric Hydrogenation of 2-Oxo-4-arylbut-3-enoic Acids by Zhu, Lvfeng, Meng, Qinghua, Fan, Weizheng, Xie, Xiaomin, Zhang, Zhaoguo

“…A challenging direct asymmetric hydrogenation of (E)-2-oxo-4-arylbut-3-enoic acids to give 2-hydroxy-4-arylbutanoic acids (85.4−91.8% ee) was achieved with a…”
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Ru-Catalyzed Asymmetric Hydrogenation of γ-Heteroatom Substituted β-Keto Esters by Fan, Weizheng, Li, Wanfang, Ma, Xin, Tao, Xiaoming, Li, Xiaoming, Yao, Ying, Xie, Xiaomin, Zhang, Zhaoguo

“…A series of enantiomerically pure γ-heteroatom substituted β-hydroxy esters were synthesized with high enantioselectivities (up to 99.1% ee) by hydrogenation…”
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Highly enantioselective hydrogenation of 2-oxo-4-arybutanoic acids to 2-hydroxy-4-arylbutanoic acids by Zhu, Lufeng, Chen, Houhe, Meng, Qinghua, Fan, Weizheng, Xie, Xiaomin, Zhang, Zhaoguo

“…The Ru-catalyzed asymmetric hydrogenation of 2-oxo-4-arybutanoic acids to afford 2-hydroxy-4-arybutanoic acids was accomplished by employing SunPhos as chiral…”
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Synthesis of (S)-7-Amino-5-azaspiro[2.4]heptane via Highly Enantioselective Hydrogenation of Protected Ethyl 1-(2-Aminoaceto)cyclopropanecarboxylates by Yao, Ying, Fan, Weizheng, Li, Wanfang, Ma, Xin, Zhu, Lvfeng, Xie, Xiaomin, Zhang, Zhaoguo

“…Highly effective asymmetric hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropane carboxylates in the presence of [RuCl(benzene)(S)-SunPhos]Cl was…”
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Ru-catalyzed highly enantioselective hydrogenation of α-keto Weinreb amides by Zhao, MengMeng, Li, WanFang, Ma, Xin, Fan, WeiZheng, Tao, XiaoMing, Li, XiaoMing, Xie, XiaoMin, Zhang, ZhaoGuo

“…Asymmetric hydrogenation of α-keto Weinreb amides has been realized with [Ru(( S )-Sunphos)(benzene)Cl]Cl as the catalyst and CeCl 3 ·7H 2 O as the additive. A…”
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Catalytic Asymmetric Hydrogenation of Ethyl 2-(Benzo[b]thiophen-5-yl)-2-oxoacetate with Ru-SunPhos in the Formal Synthesis of T-588 by Li, Xiaoming, Ma, Xin, Li, Wanfang, Tao, Xiaoming, Meng, Qinghua, Fan, Weizheng, Zhang, Zhaoguo

“…Application of catalytic asymmetric hydrogenation of ethyl 2‐(benzo[b]thiophen‐5‐yl)‐2‐oxoacetate for the formal synthesis of cognitive enhancer T‐588 is…”
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CO2‑Responsive Polymer Single-Chain Nanoparticles and Self-Assembly for Gas-Tunable Nanoreactors by Fan, Weizheng, Tong, Xia, Farnia, Farhad, Yu, Bing, Zhao, Yue

“…CO2-responsive polymer single-chain nanoparticles (SCNPs) and self-assembled micellar aggregates are investigated as gas-controlled, rate- and size-tunable…”
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Ultrasensitive pH-Induced Water Solubility Switch Using UCST Polymers by Zhang, Hu, Guo, Shengwei, Fan, Weizheng, Zhao, Yue

“…For some thermosensitive polymers, the absence of an upper critical solution temperature (UCST) in water in an accessible temperature range (say, 5–90 °C) can…”
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Design, synthesis and biological evaluation of 2-phenylaminopyrimidine derivatives as EGFR inhibitors by Tang, Chunlei, Wang, Jie, Wang, Dong, Wang, Huabing, Cui, Shengkai, Xiao, Tianxin, Fan, Weizheng, Zhang, Yan

“…[Display omitted] •New 2-phenylaminopyrimidine derivatives were designed and synthesized.•EGFRL858R/T790M/C797S inhibitory activity and antiproliferative…”
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Gelation of Triblock Copolymers in Aqueous Solution through CO2‐Triggered Electrostatic Interaction by Yu, Bing, Fan, Weizheng, Zhao, Yue

“…Polymer systems displaying CO2‐triggered rheology alteration are widely investigated in recent years, which can change from nonviscous liquid to high‐viscosity…”
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An efficient one-pot, three-component synthesis of vinyl sulfones via iodide-catalyzed radical alkenylation by Fan, Weizheng, Su, Jiapeng, Shi, Dongyang, Feng, Bainian

“…An efficient one-pot, three-component synthesis of vinyl sulfones via iodide-catalyzed radical alkenylation using aryl diazonium salts, terminal alkenes and…”
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Pyrizolo[1,5-a]pyrimidine derivatives of the second-generation TRK inhibitor: Design, synthesis and biological evaluation by Fan, Yiqing, Zhang, Yongjie, Liu, Yan, Jiang, Hongyu, Zhou, Ying, Tang, Chunlei, Fan, Weizheng

“…[Display omitted] •New pyrido[1,2-α]pyrazole derivatives were designed and synthesized.•Wild-type TrkA, TrkAG595R and Alk inhibitory activity in vitro were…”
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Design, synthesis and biological evaluation of quinazoline SOS1 inhibitors by Jiang, Hongyu, Fan, Yiqing, Wang, Xia, Wang, Jie, Yang, Haifan, Fan, Weizheng, Tang, Chunlei

“…[Display omitted] Son of sevenless 1 (SOS1) is a vital guanine nucleotide exchange factor (GEFs) that activates rat sarcoma (Ras) protein in cells. SOS1…”
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Pyrazolo[1,5-a]pyrimidine based Trk inhibitors: Design, synthesis, biological activity evaluation by Zhang, Yongjie, Liu, Yan, Zhou, Ying, Zhang, Qing, Han, Tianfu, Tang, Chunlei, Fan, Weizheng

“…[Display omitted] •Novel pyrazolo[1,5-a]pyrimidine derivatives were designed and synthesized.•TrkA, TrkB and TrkC inhibitory activity were evaluated.•Compounds…”
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Making Nanocomposites of Hydrophilic and Hydrophobic Polymers Using Gas‐Responsive Cellulose Nanocrystals by Farnia, Farhad, Fan, Weizheng, Dory, Yves, Zhao, Yue

“…Generally, different surface‐functionalized cellulose nanocrystals (CNC) are required for use as nanofillers in hydrophilic and hydrophobic polymers. In the…”
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Immobilizing of oxo-molybdenum complex on cross-linked copolymer and its catalytic activity for epoxidation reactions by Fan, Weizheng, Shi, Dongyang, Feng, Bainian

“…This work describes the immobilization of molybdenum acetylacetonate oxygen (MoO2(acac)2) on cross-linked porous copolymer support via covalent attachment…”
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