Search Results - "Fan, Sibin"

Expansion of human megakaryocyte-biased hematopoietic stem cells by biomimetic Microniche by Li, Yinghui, He, Mei, Zhang, Wenshan, Liu, Wei, Xu, Hui, Yang, Ming, Zhang, Hexiao, Liang, Haiwei, Li, Wenjing, Wu, Zhaozhao, Fu, Weichao, Xu, Shiqi, Liu, Xiaolei, Fan, Sibin, Zhou, Liwei, Wang, Chaoqun, Zhang, Lele, Li, Yafang, Gu, Jiali, Yin, Jingjing, Zhang, Yiran, Xia, Yonghui, Mao, Xuemei, Cheng, Tao, Shi, Jun, Du, Yanan, Gao, Yingdai

“…Limited numbers of available hematopoietic stem cells (HSCs) limit the widespread use of HSC-based therapies. Expansion systems for functional heterogenous…”
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Ixazomib‐based maintenance therapy after bortezomib‐based induction in patients with multiple myeloma not undergoing transplantation: A real‐world study by Shen, Man, Zhang, Jiajia, Tang, Ran, Wang, Yuhao, Zhan, Xiaokai, Fan, Sibin, Huang, Zhongxia, Zhong, Yuping, Li, Xin

“…Background Maintenance therapy with proteasome inhibitors (PIs) can improve outcomes of multiple myeloma (MM) patients, however, the neurotoxicity and…”
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Single-cell transcriptomics dissects hematopoietic cell destruction and T-cell engagement in aplastic anemia by Zhu, Caiying, Lian, Yu, Wang, Chenchen, Wu, Peng, Li, Xuan, Gao, Yan, Fan, Sibin, Ai, Lanlan, Fang, Liwei, Pan, Hong, Cheng, Tao, Shi, Jun, Zhu, Ping

“…Aplastic anemia (AA) is a T cell–mediated autoimmune disorder of the hematopoietic system manifested by severe depletion of the hematopoietic stem and…”
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Detection of lenalidomide metabolites in urine to discover drug-resistant compounds by Zhan, Xiaokai, Liu, Xikun, Rang, Li, Shen, Man, Zhang, Jiajia, Tang, Ran, Fan, Sibin, Zhao, Fengyi, Li, Xin, Zhang, Xiaoying, Huang, Zhongxia, Zhang, Sen

“…•The difference in the efficacy of lenalidomide is related to metabolites.•Ultra-performance liquid chromatography–time-of-flight tandem mass spectrometry…”
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SCREENING AND VERIFICATION OF ANTIOXIDANT SMALL MOLECULAR COMPOUNDS FOR EXPANSION OF HUMAN HEMATOPOIETIC STEM CELLS EX VITRO by Zhang, Wenshan, He, Mei, Fan, Sibin, Song, Henan, Ding, Yahui, Yang, Ming, Ji, Qing, Li, Yinghui, Gao, Yingdai

“…Objective: To screen the antioxidant small molecular compounds with optimal efficiency of expanding hHSC ex vitro based on antioxidant small molecular compound…”
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Survival and Prognosis Analysis of Bortezomib Based Regimen in Newly Diagnosed Super-aged Multiple Myeloma Patients by ZHAO Fengyi, LI Xin, ZHAN Xiaokai, ZHANG Jiajia, SHEN Man, TANG Ran, FAN Sibin, HUANG Zhongxia

“…Background Multiple myeloma is a highly heterogeneous disease. Super-aged patients with multiple myeloma are a special group. There is a lack of evidence-based…”
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Efficacy and Safety of Dual-targeted Chimeric Antigen Receptor-T Cell Therapy in Patients with Refractory-relapsed Multiple Myeloma: a Meta-analysis by YU Haibo, ZHANG Tianyu, LI Xin, ZHANG Jiajia, SHEN Man, ZHAN Xiaokai, TANG Ran, FAN Sibin, ZHAO Fengyi, HUANG Zhongxia

“…Background Chimeric antigen receptor (CAR) -T cell immunotherapy has achieved good therapeutic effect in multiple myeloma (MM) , and the most common target is…”
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Hepcidin for iron homeostasis and target therapy in ironrelated disorders by Fan, Sibin, Zheng, Yizhou, Shi, Jun

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初诊超高龄多发性骨髓瘤患者硼替佐米基础方案治疗的生存预后分析 by 赵凤仪, 李新, 詹晓凯, 张佳佳, 申曼, 汤然, 范斯斌, 黄仲夏

“…R733.3; 背景 多发性骨髓瘤(MM)是一种高度异质性疾病,超高龄老年MM患者是一类特殊群体,其治疗决策和一般评价缺乏一定的循证医学依据,在衰弱评估方面也有一定争议.目的 分析以硼替佐米为基础方案治疗初诊超高龄MM患者的一般临床特征和生存预后的影响因素,同时评价超高龄MM患者一般状况的最佳评估模式.方法回顾性分析…”
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双靶点嵌合抗原受体-T细胞治疗复发难治多发性骨髓瘤患者疗效和安全性的Meta分析 by 于海搏, 张天宇, 李新, 张佳佳, 申曼, 詹晓凯, 汤然, 范斯斌, 赵凤仪, 黄仲夏

“…R733.3; 背景…”
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Hepcidin调控铁稳态分子机制及其靶向治疗铁代谢失衡 by 范斯斌 郑以州 施均

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地中海贫血合并获得性骨髓衰竭12例临床诊断及治疗转归 by 范斯斌;施均;聂能;邵英起;黄振东;张静;黄金波;李星鑫;葛美丽;郑以州

“…地中海贫血（地贫）是一类血红蛋白编码基因突变或缺失导致珠蛋白α或β肽链合成不足或缺如的慢性溶血性贫血，多伴阳性家族史。…”
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意义未明克隆性血细胞减少症临床诊断研究 by 施均 聂能 黄振东 范斯斌 邵英起 张静 黄金波 李星鑫 葛美丽 郑以州

“…获得性骨髓造血衰竭综合征的临床诊断及鉴别诊断是比较难以准确把握的临床问题，相当一部分患者的临床特征不典型，与目前再生障碍性贫血（AA）、骨髓增生异常综合征（MDS）的诊断标准不符。Wimazal等[1]及Valent等[2]提出意义未明特发性血细胞减少症（Idiopathic cytopenia of…”
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复发/难治自身免疫性溶血性贫血患者脾切除术疗效分析 by 范斯斌, 王志军, 毛强, 童春帆, 翟伟涛, 郑以州, 孙朝侠, 施均

“…目的 评估脾切术治疗复发/难治自身免疫性溶血性贫血(AIHA)患者的疗效.方法 回顾性分析中国医学科学院血液病医院30例行脾切除术治疗的复发/难治自身免疫性溶血性贫血(AIHA)患者的临床资料,评估手术疗效.结果 30例复发/难治AIHA患者中,单纯AIHA…”
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