Search Results - "Fan, Rebecca Z"

Mitochondrial division inhibitor-1 is neuroprotective in the A53T-α-synuclein rat model of Parkinson’s disease by Bido, Simone, Soria, Federico N., Fan, Rebecca Z., Bezard, Erwan, Tieu, Kim

“…Alpha-synuclein (α-syn) is involved in both familial and sporadic Parkinson’s disease (PD). One of the proposed pathogenic mechanisms of α-syn mutations is…”
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Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo by Rappold, Phillip M., Cui, Mei, Grima, Jonathan C., Fan, Rebecca Z., de Mesy-Bentley, Karen L., Chen, Linan, Zhuang, Xiaoxi, Bowers, William J., Tieu, Kim

“…Mitochondrial dysfunction has been reported in both familial and sporadic Parkinson’s disease (PD). However, effective therapy targeting this pathway is…”
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Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition by Fan, Rebecca Z, Guo, Min, Luo, Shouqing, Cui, Mei, Tieu, Kim

“…Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson's disease (PD) has been intensively pursued largely due to its well-recognized…”
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A partial Drp1 knockout improves autophagy flux independent of mitochondrial function by Fan, Rebecca Z, Sportelli, Carolina, Lai, Yanhao, Salehe, Said S, Pinnell, Jennifer R, Brown, Harry J, Richardson, Jason R, Luo, Shouqing, Tieu, Kim

“…Dynamin-related protein 1 (Drp1) plays a critical role in mitochondrial dynamics. Partial inhibition of this protein is protective in experimental models of…”
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Exosome release and neuropathology induced by [alpha]-synuclein: new insights into protective mechanisms of Drp1 inhibition by Fan, Rebecca Z, Guo, Min, Luo, Shouqing, Cui, Mei, Tieu, Kim

“…Targeting alpha-synuclein ([alpha]-syn) as a therapeutic strategy for Parkinson's disease (PD) has been intensively pursued largely due to its well-recognized…”
Get full text