Search Results - "Fan, Qiying"

Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance by Mao, Hua, Li, Luge, Fan, Qiying, Angelini, Aude, Saha, Pradip K., Wu, Huaizhu, Ballantyne, Christie M., Hartig, Sean M., Xie, Liang, Pi, Xinchun

“…Accumulating evidence suggests that chronic inflammation of metabolic tissues plays a causal role in obesity-induced insulin resistance. Yet, how specific…”
Get full text

Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin by Mao, Hua, Li, Luge, Fan, Qiying, Angelini, Aude, Saha, Pradip K., Coarfa, Cristian, Rajapakshe, Kimal, Perera, Dimuthu, Cheng, Jizhong, Wu, Huaizhu, Ballantyne, Christie M., Sun, Zheng, Xie, Liang, Pi, Xinchun

“…The vascular endothelium is present within metabolic organs and actively regulates energy metabolism. Here we show osteocalcin, recognized as a bone-secreted…”
Get full text

Depletion of Endothelial Prolyl Hydroxylase Domain Protein 2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction by Fan, Qiying, Mao, Hua, Angelini, Aude, Coarfa, Cristian, Robertson, Matthew J, Lagor, William R, Wehrens, Xander H.T, Martin, James F, Pi, Xinchun, Xie, Liang

Get full text

Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis by Valenzuela, Nicolas, Fan, Qiying, Fa'ak, Faisal, Soibam, Benjamin, Nagandla, Harika, Liu, Yu, Schwartz, Robert J, McConnell, Bradley K, Stewart, M David

“…HIRA is the histone chaperone responsible for replication-independent incorporation of histone variant H3.3 within gene bodies and regulatory regions of…”
Get full text

Prolyl Hydroxylase Domain-2 Protein Regulates Lipopolysaccharide-Induced Vascular Inflammation by Fan, Qiying, Mao, Hua, Xie, Liang, Pi, Xinchun

“…Acute lung injury and its more severe form, acute respiratory distress syndrome, are life-threatening respiratory disorders. Overwhelming pulmonary…”
Get full text

Myocardial Rev-erb–Mediated Diurnal Metabolic Rhythm and Obesity Paradox by Song, Shiyang, Tien, Chih-Liang, Cui, Hao, Basil, Paul, Zhu, Ningxia, Gong, Yingyun, Li, Wenbo, Li, Hui, Fan, Qiying, Min Choi, Jong, Luo, Weijia, Xue, Yanfeng, Cao, Rui, Zhou, Wenjun, Ortiz, Andrea R., Stork, Brittany, Mundra, Vatsala, Putluri, Nagireddy, York, Brian, Chu, Maoping, Chang, Jiang, Yun Jung, Sung, Xie, Liang, Song, Jiangping, Zhang, Lilei, Sun, Zheng

“…The nuclear receptor Rev-erbα/β, a key component of the circadian clock, emerges as a drug target for heart diseases, but the function of cardiac Rev-erb has…”
Get full text

LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation by Lockyer, Pamela, Mao, Hua, Fan, Qiying, Li, Luge, Yu-Lee, Li-Yuan, Eissa, N Tony, Patterson, Cam, Xie, Liang, Pi, Xinchun

“…OBJECTIVE—Bacterial endotoxin (lipopolysaccharide)-mediated sepsis involves dysregulated systemic inflammation, which injures the lung and other organs, often…”
Get full text

Depletion of Endothelial PHD2 and 3 Promotes Cardiomyocyte Proliferation and Prevents Ventricular Failure Induced by Myocardial Infarction by Fan, Qiying, Mao, Hua, Angelini, Aude, Coarfa, Cristian, Robertson, Matthew J, Lagor, William R., Wehrens, Xander H.T., Martin, James F., Pi, Xinchun, Xie, Liang

Get full text

Myocardial Rev-erb-Mediated Diurnal Metabolic Rhythm and Obesity Paradox by Song, Shiyang, Tien, Chih-Liang, Cui, Hao, Basil, Paul, Zhu, Ningxia, Gong, Yingyun, Li, Wenbo, Li, Hui, Fan, Qiying, Choi, Jong Min, Luo, Weijia, Xue, Yanfeng, Cao, Rui, Zhou, Wenjun, Ortiz, Andrea R., Stork, Brittany, Mundra, Vatsala, Putluri, Nagireddy, York, Brian, Chu, Maoping, Chang, Jiang, Jung, Sung Yun, Xie, Liang, Song, Jiangping, Zhang, Lilei, Sun, Zheng

Get full text

Absence of gravin-mediated signaling inhibits development of high-fat diet-induced hyperlipidemia and atherosclerosis by Fan, Qiying, Yin, Xing, Rababa'h, Abeer, Diaz Diaz, Andrea, Wijaya, Cori S, Singh, Sonal, Suryavanshi, Santosh V, Vo, Henry Hiep, Saeed, Moawiz, Zhang, Yang, McConnell, Bradley K

“…Gravin, an A-kinase anchoring protein, is known to play a role in regulating key processes that lead to inflammation and atherosclerosis development, namely,…”
Get more information

Characterization of vascular smooth muscle cell function in Gravin (AKAP12) truncated mice model in response to angiotensin‐II (866.7) by Fan, Qiying, Wijaya, Cori, Diaz Diaz, Andrea, McConnell, Bradley

“…Vascular smooth muscle cells (VSMCs), plays a crucial role in the progression of atherosclerosis in response to angiotensin II (Ang II). Gravin, one of the…”
Get full text

Gravin Scaffolding Protein Mediates Signaling Involved in theRegulation of Hyperlipidemia and Atherosclerosis by Fan, Qiying, Wijaya, Cori, Diaz Diaz, Andrea, Vo, Hiep, McConnell, Bradley

“…Abstract only Atherosclerosis is a leading health problem and contributes to cardiovascular related mortality. Furthermore, hyperlipidemia is a major…”
Get full text

Role of Calcium Sensitivity of Troponin C in the Development of Dilated Cardiomyopathy by Tikunova, Svetlana, Singh, Sonal, Fan, Qiying, Hernandez, Adriana, Portillo, Jesus, McConnell, Bradley

“…Abstract only Dilated cardiomyopathy (DCM) is a disease of cardiac muscle characterized by left ventricular dilation and systolic dysfunction. In 30‐40% of all…”
Get full text

Gravin mutant mice show resistance to the development and progression of cardiac hypertrophy (837.12) by Singh, Sonal, Diaz Diaz, Andrea, Wijaya, Cori, Suryavanshi, Santosh, Fan, Qiying, McConnell, Bradley

“…Gravin, an A kinase anchoring protein is involved in the desensitization cycle of the β2‐adrenergic receptors (β2‐ARs) upon agonist stimulation via localized…”
Get full text

Gravin Scaffolding Protein Mediates Signaling in High Fat Diet Model by Fan, Qiying, Diaz, Andrea C Diaz, Wijaya, Cori S, Yin, Xing, Singh, Sonal, McConnell, Bradley K

“…Abstract only Atherosclerosis is an inflammatory response principally in the walls of arteries contributing to cardiovascular related mortality, which can be…”
Get full text

Protein Kinase A and Phosphodiesterase-4D3 Binding to Coding Polymorphisms of Cardiac Muscle Anchoring Protein (mAKAP) by Rababa'h, Abeer, Craft, John W., Wijaya, Cori S., Atrooz, Fatin, Fan, Qiying, Singh, Sonal, Guillory, Ashley N., Katsonis, Panagiotis, Lichtarge, Olivier, McConnell, Bradley K.

“…Protein kinase A (PKA) substrate phosphorylation is facilitated through its co-localization with its signaling partner by A-kinase anchoring proteins (AKAPs)…”
Get full text

Knock-in mice harboring a Ca2+ desensitizing mutation in cardiac troponin C develop early onset dilated cardiomyopathy by McConnell, Bradley K., Singh, Sonal, Fan, Qiying, Hernandez, Adriana, Portillo, Jesus P., Reiser, Peter J., Tikunova, Svetlana B.

“…The physiological consequences of aberrant Ca 2+ binding and exchange with cardiac myofilaments are not clearly understood. In order to examine the effect of…”
Get full text

Cardiac Scaffold Protein Binding Kinetics: A Role For Altered Signaling During Human Heart Disease by Rababah, Abeer, Craft, John, Guillory, Ashley, Wijaya, Cori, Singh, Sonal, Fan, Qiying, Diaz, Andrea Diaz, Yin, Xing, McConnell, Bradley

“…Abstract only Cardiac contractility is physiologically modulated primarily through beta‐adrenergic (β‐AR) receptor signaling. Beta‐adrenergic stimulation…”
Get full text

Knock-in mice harboring a Ca(2+) desensitizing mutation in cardiac troponin C develop early onset dilated cardiomyopathy by McConnell, Bradley K, Singh, Sonal, Fan, Qiying, Hernandez, Adriana, Portillo, Jesus P, Reiser, Peter J, Tikunova, Svetlana B

“…The physiological consequences of aberrant Ca(2+) binding and exchange with cardiac myofilaments are not clearly understood. In order to examine the effect of…”
Get full text