Search Results - "Fan, Matthew"

A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells by Li, Xue, Jiang, Quan, Song, Guiyu, Barkestani, Mahsa Nouri, Wang, Qianxun, Wang, Shaoxun, Fan, Matthew, Fang, Caodi, Jiang, Bo, Johnson, Justin, Geirsson, Arnar, Tellides, George, Pober, Jordan S., Jane-wit, Dan

“…Internalization of complement membrane attack complexes (MACs) assembles NLRP3 inflammasomes in endothelial cells (EC) and promotes IL-β-mediated tissue…”
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Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells by Li, Xue, Jiang, Quan, Song, Guiyu, Barkestani, Mahsa Nouri, Wang, Qianxun, Wang, Shaoxun, Fan, Matthew, Fang, Caodi, Jiang, Bo, Johnson, Justin, Geirsson, Arnar, Tellides, George, Pober, Jordan S., Jane-wit, Dan

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Author Correction: A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells by Li, Xue, Jiang, Quan, Song, Guiyu, Barkestani, Mahsa Nouri, Wang, Qianxun, Wang, Shaoxun, Fan, Matthew, Fang, Caodi, Jiang, Bo, Johnson, Justin, Geirsson, Arnar, Tellides, George, Pober, Jordan S., Jane-wit, Dan

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Membrane attack complexes, endothelial cell activation, and direct allorecognition by Song, Guiyu, Wang, Shaoxun, Barkestani, Mahsa Nouri, Mullan, Clancy, Fan, Matthew, Jiang, Bo, Jiang, Quan, Li, Xue, Jane-Wit, Dan

“…Endothelial cells (ECs) form a critical immune interface regulating both the activation and trafficking of alloreactive T cells. In the setting of solid organ…”
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Hedgehog costimulation during ischemia-reperfusion injury potentiates cytokine and homing responses of CD4 + T cells by Wang, Shaoxun, Song, Guiyu, Barkestani, Mahsa Nouri, Tobiasova, Zuzana, Wang, Qianxun, Jiang, Quan, Lopez, Roberto, Adelekan-Kamara, Yasmin, Fan, Matthew, Pober, Jordan S, Tellides, George, Jane-Wit, Dan

“…Ischemia reperfusion injury (IRI) confers worsened outcomes and is an increasing clinical problem in solid organ transplantation. Previously, we identified a…”
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Melatonin ameliorates retinal ganglion cell senescence and apoptosis in a SIRT1-dependent manner in an optic nerve injury model by Shi, Yuxun, Ye, Dan, Cui, Kaixuan, Bai, Xue, Fan, Matthew, Feng, Yanlin, Hu, Chenyang, Xu, Yue, Huang, Jingjing

“…Melatonin is involved in exerting protective effects in aged-related and neurodegenerative diseases through a silent information regulator type 1…”
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Anti‐PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model by Ye, Dan, Xu, Yue, Shi, Yuxun, Fan, Matthew, Lu, Peng, Bai, Xue, Feng, Yanlin, Hu, Chenyang, Cui, Kaixuan, Tang, Xiaoyu, Liao, Jing, Huang, Wei, Xu, Fan, Liang, Xiaoling, Huang, Jingjing

“…Acute ocular hypertension (AOH) is the most important characteristic of acute glaucoma, which can lead to retinal ganglion cell (RGC) death and permanent…”
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Therapeutic Benefit of Melatonin in Choroidal Neovascularization During Aging Through the Regulation of Senescent Macrophage/Microglia Polarization by Cui, Kaixuan, Tang, Xiaoyu, Hu, Andina, Fan, Matthew, Wu, Peiqi, Lu, Xi, Lin, Jicheng, Yang, Fengmei, Zhao, Xinyu, Huang, Jingjing, Yu, Shanshan, Xu, Yue, Liang, Xiaoling

“…This study aimed to investigate the age-dependent anti-angiogenic capability of melatonin in choroidal neovascularization (CNV) and to explore the underlying…”
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Sema4D Knockout Attenuates Choroidal Neovascularization by Inhibiting M2 Macrophage Polarization Via Regulation of the RhoA/ROCK Pathway by Cui, Kaixuan, Tang, Xiaoyu, Yang, Boyu, Fan, Matthew, Hu, Andina, Wu, Peiqi, Yang, Fengmei, Lin, Jicheng, Kong, Haolin, Lu, Xi, Yu, Shanshan, Xu, Yue, Liang, Xiaoling

“…The aim of this study was to elucidate the role of Sema4D in the pathogenesis of senescence-associated choroidal neovascularization (CNV) and to explore its…”
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GSK840 Alleviates Retinal Neuronal Injury by Inhibiting RIPK3/MLKL-Mediated RGC Necroptosis After Ischemia/Reperfusion by Feng, Yanlin, Hu, Chenyang, Cui, Kaixuan, Fan, Matthew, Xiang, Wu, Ye, Dan, Shi, Yuxun, Ye, Huiwen, Bai, Xue, Wei, Yantao, Xu, Yue, Huang, Jingjing

“…PurposeThis study aimed to explore the impact of GSK840 on retinal neuronal injury after retinal ischemia/reperfusion (IR) and its associated…”
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Neuroprotection of SRT2104 in Murine Ischemia/Reperfusion Injury Through the Enhancement of Sirt1-Mediated Deacetylation by Bai, Xue, Ye, Dan, Shi, Yuxun, Fan, Matthew, Lu, Peng, Feng, Yanlin, Hu, Chenyang, Liao, Jing, Cui, Kaixuan, Tang, Xiaoyu, Wu, Peiqi, Xu, Fan, Xu, Yue, Huang, Jingjing

“…Strategies for neuroprotection are the main targets of glaucoma research. The neuroprotective properties of SRT2104 administration have been proven in central…”
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Melatonin prevents EAAC1 deletion‐induced retinal ganglion cell degeneration by inhibiting apoptosis and senescence by Hu, Chenyang, Feng, Yanlin, Huang, Guangyi, Cui, Kaixuan, Fan, Matthew, Xiang, Wu, Shi, Yuxun, Ye, Dan, Ye, Huiwen, Bai, Xue, Xu, Fan, Xu, Yue, Huang, Jingjing

“…Normal tension glaucoma (NTG) is referred to as a progressive degenerative disorder of the retinal ganglion cells (RGCs), resulting in nonreversible visual…”
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ZFYVE21 promotes endothelial nitric oxide signaling and vascular barrier function in the kidney during aging by Jiang, Quan, Song, Guiyu, He, Liying, Li, Xue, Jiang, Bo, Wang, Qianxun, Wang, Shaoxun, Kim, Catherine, Barkestani, Mahsa Nouri, Lopez, Roberto, Fan, Matthew, Wanniarachchi, Kujani, Quaranta, Maya, Tian, Xuefei, Mani, Arya, Gonzalez, Anjelica, Goodwin, Julie E, Sessa, William C, Ishibe, Shuta, Jane-Wit, Dan

“…ZFYVE21 is an ancient, endosome-associated protein that is highly expressed in endothelial cells (ECs) but whose function(s) in vivo are undefined. Here, we…”
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Hedgehog-induced ZFYVE21 promotes chronic vascular inflammation by activating NLRP3 inflammasomes in T cells by Jiang, Bo, Wang, Shaoxun, Song, Guiyu, Jiang, Quan, Fan, Matthew, Fang, Caodi, Li, Xue, Soh, Chien Lin, Manes, Thomas D, Cheru, Nardos, Qin, Lingfeng, Ren, Pengwei, Jortner, Bianca, Wang, Qianxun, Quaranta, Emma, Yoo, Peter, Geirsson, Arnar, Davis, Robert P, Tellides, George, Pober, Jordan S, Jane-Wit, Dan

“…The zinc finger protein ZFYVE21 is involved in immune signaling. Using humanized mouse models, primary human cells, and patient samples, we identified a T…”
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Towards Autonomous Control of Magnetic Suture Needles by Fan, Matthew, Liu, Xiaolong, Jain, Kamakshi, Lerner, Daniel, Mair, Lamar O., Weinberg, Irving N., Diaz-Mercado, Yancy, Krieger, Axel

“…This paper proposes a magnetic needle steering controller to manipulate mesoscale magnetic suture needles for executing planned suturing motion. This is an…”
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Acrizanib as a Novel Therapeutic Agent for Fundus Neovascularization via Inhibitory Phosphorylation of VEGFR2 by Tang, Xiaoyu, Cui, Kaixuan, Wu, Peiqi, Hu, Andina, Fan, Matthew, Lu, Xi, Yang, Fengmei, Lin, Jicheng, Yu, Shanshan, Xu, Yue, Liang, Xiaoling

“…The present study aimed to evaluate the effect of acrizanib, a small molecule inhibitor targeting vascular endothelial growth factor receptor 2 (VEGFR2), on…”
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Choroidal Vortex Vein Drainage System in Central Serous Chorioretinopathy Using Ultra-Widefield Optical Coherence Tomography Angiography by Luo, Zhonghua, Xu, Yue, Xu, Kun, Fan, Matthew, Tsui, Ching-Kit, Lu, Xi, Wu, Benjuan, Zhao, Xinyu, Tang, Xiaoyu, Wu, Peiqi, Cui, Kaixuan, Yu, Shanshan, Liang, Xiaoling

“…PurposeTo evaluate differences in the choroidal vortex vein drainage system (VV) in eyes between patients with central serous chorioretinopathy (CSC) and…”
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A real-time platform for contextualized conspiracy theory analysis by Chong, David, Lee, Erl, Fan, Matthew, Holur, Pavan, Shahsavari, Shadi, Tangherlini, Timothy, Roychowdhury, Vwani

“…As the U.S. Capitol riots of January 6, 2021 attest, conspiracy theories can lead to civil unrest. Many "netizens" of the radical online fora that host these…”
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Activated Alleles of the Schizosaccharomyces pombe gpa2+ G Gene Identify Residues Involved in GDP-GTP Exchange by Ivey, Francis XTaglia Fan Yang Matthew MLander David AKelly FDouglas, Hoffman, Charles S

“…The Schizosaccharomyces pombe glucose/cyclic AMP (cAMP) signaling pathway includes the Gpa2-Git5-Git11 heterotrimeric G protein, whose Gpa2 G subunit directly…”
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