Search Results - "Fan, Jinzhu"
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Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-κB signaling pathway in osteoblasts
Published in BMC musculoskeletal disorders (11-04-2022)“…The purpose of this study was to determine the role of Orai1 in the regulation of the proliferation and cell cycle of osteoblasts. The expression of Orai1 was…”
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MYC inhibition reprograms tumor immune microenvironment by recruiting T lymphocytes and activating the CD40/CD40L system in osteosarcoma
Published in Cell death discovery (15-03-2022)“…The efficacy of immune checkpoint blockade (ICB) therapy depends on sufficient infiltration and activation of primed tumor-specific cytotoxic T lymphocytes…”
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The CtIP-CtBP1/2-HDAC1-AP1 transcriptional complex is required for the transrepression of DNA damage modulators in the pathogenesis of osteosarcoma
Published in Translational oncology (01-07-2022)“…•CtIP couples with CtBP1/2 heterodimer, HDAC1, and two subunits of AP1 transcription factor to assemble a complex.•The CtIP-CtBP1/2-HDAC1-AP1 complex is…”
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Orai1 downregulation causes proliferation reduction and cell cycle arrest via inactivation of the Ras-NF-?B signaling pathway in osteoblasts
Published in BMC musculoskeletal disorders (11-04-2022)“…Background The purpose of this study was to determine the role of Orai1 in the regulation of the proliferation and cell cycle of osteoblasts. Methods The…”
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MicroRNA-34c promotes osteoclast differentiation through targeting LGR4
Published in Gene (30-04-2017)“…MicroRNAs have emerged as important regulators of osteoclast differentiation in recent years. Of these, miR-34c has been reported to play an important role in…”
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Downregulation of Bach1 protects osteoblasts against hydrogen peroxide-induced oxidative damage in vitro by enhancing the activation of Nrf2/ARE signaling
Published in Chemico-biological interactions (25-08-2019)“…Oxidative-stress-induced osteoblast dysfunction plays an important role in the development and progression of osteoporosis. BTB and CNC homology 1 (Bach1) has…”
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Approach to osteomyelitis treatment with antibiotic loaded PMMA
Published in Microbial pathogenesis (01-01-2017)“…To reduce the incidence of osteomyelitis infection, local antibiotic impregnated delivery systems are commonly used as a promising and effective approach to…”
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WITHDRAWN: Characterization of Ag2O nanorods/TiO2 nanotubes hybrid coating for potential orthopedic implant applications
Published in Results in physics (01-10-2024)Get full text
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Orai1 Promotes Osteosarcoma Metastasis by Activating the Ras-Rac1-WAVE2 Signaling Pathway
Published in Medical science monitor (04-12-2019)“…BACKGROUND The purpose of this study was to investigate whether Orai1 plays a role in the metastasis of osteosarcoma. MATERIAL AND METHODS The expression of…”
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Blockade of interleukin 6 by rat anti-mouse interleukin 6 receptor antibody promotes fracture healing
Published in Biochemistry (Moscow) (01-10-2017)“…Level of interleukin 6 (IL-6) is associated with fracture healing. This study was performed to explore the effect of IL-6 blockade on fracture healing…”
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MicroRNA-499a-5p inhibits osteosarcoma cell proliferation and differentiation by targeting protein phosphatase 1D through protein kinase B/glycogen synthase kinase 3β signaling
Published in Oncology letters (01-04-2018)“…A number of studies have attempted to elucidate the association between mircoRNAs (miRNAs/miRs) and cancer-associated processes. The aim of the present study…”
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Targeting the CtBP1-FOXM1 transcriptional complex with small molecules to overcome MDR1-mediated chemoresistance in osteosarcoma cancer stem cells
Published in Journal of Cancer (01-01-2021)“…Chemoresistance is a major barrier for the chemotherapy of osteosarcoma. The induction of multidrug resistance protein 1 (MDR1), an ATP-dependent transporter,…”
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Ginsenoside Rb2 inhibits osteoclast differentiation through nuclear factor-kappaB and signal transducer and activator of transcription protein 3 signaling pathway
Published in Biomedicine & pharmacotherapy (01-08-2017)“…Abstract Ginsenoside-Rb2 (Rb2) is a 20( S )-protopanaxadiol glycoside extracted from ginseng possessing various bioactivities which has drawn considerable…”
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MicroRNA-499a-5p inhibits osteosarcoma cell proliferation and differentiation by targeting protein phosphatase 1D through protein kinase B/glycogen synthase kinase 3[beta] signaling
Published in Oncology letters (01-04-2018)“…A number of studies have attempted to elucidate the association between mircoRNAs (miRNAs/miRs) and cancer-associated processes. The aim of the present study…”
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Flap combined with induced membrane technique in treatment of post-traumatic tibial osteomyelitis with soft tissue defect
Published in Zhongguo xiu fu chong jian wai ke za zhi (15-05-2022)“…To investigate the effectiveness of flap combined with induced membrane technique in treatment of post-traumatic tibial osteomyelitis with soft tissue defect…”
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Treatment of Gustilo-Anderson ⅢB type injury of distal femur complicated with bone defect by membrane induction technique
Published in Zhongguo xiu fu chong jian wai ke za zhi (15-05-2022)“…To evaluate the effectiveness of membrane induction technique in the treatment of Gustilo-Anderson ⅢB type injury of distal femur complicated with bone…”
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Treatment of Gustilo-Anderson Ⅲ B type injury of distal femur complicated with bone defect by membrane induction technique
Published in Zhongguo xiu fu chong jian wai ke za zhi (15-05-2022)“…To evaluate the effectiveness of membrane induction technique in the treatment of Gustilo-Anderson ⅢB type injury of distal femur complicated with bone defect…”
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Prediction of Users 9 Participation Willingness in Electric Energy Substitution Under Energy Market
Published in 2018 International Conference on Power System Technology (POWERCON) (01-11-2018)“…In order to effectively implement electric energy substitution (EES) and expand the electricity consumption market, it is important to analyze users'…”
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