Search Results - "Fan, Isabella Y."

Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment by Poznanski, Sophie M, Singh, Kanwaldeep, Ritchie, Tyrah M, Aguiar, Jennifer A, Fan, Isabella Y, Portillo, Ana L, Rojas, Eduardo A, Vahedi, Fatemeh, El-Sayes, Abdullah, Xing, Sansi, Butcher, Martin, Lu, Yu, Doxey, Andrew C, Schertzer, Jonathan D, Hirte, Hal W, Ashkar, Ali A

“…NK cells are central to anti-tumor immunity and recently showed efficacy for treating hematologic malignancies. However, their dysfunction in the hostile tumor…”
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Expanded human NK cells from lung cancer patients sensitize patients’ PDL1−negative tumors to PD1-blockade therapy by Poznanski, Sophie M, Ritchie, Tyrah M, Fan, Isabella Y, El-Sayes, Abdullah, Portillo, Ana L, Ben-Avi, Ronny, Rojas, Eduardo A, Chew, Marianne V, Shargall, Yaron, Ashkar, Ali A

“…Lung cancer remains the leading cause of cancer death worldwide despite the significant progress made by immune checkpoint inhibitors, including programmed…”
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High Intensity Interval Training Increases Natural Killer Cell Number and Function in Obese Breast Cancer-challenged Mice and Obese Women by Barra, Nicole G, Fan, Isabella Y, Gillen, Jenna B, Chew, Marianne, Marcinko, Katarina, Steinberg, Gregory R, Gibala, Martin J, Ashkar, Ali A

“…High intensity interval training (HIIT) boosts natural killer (NK) cell number and activity in normal weight breast cancer patients; however, whether this…”
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The association between fetal head station at the first diagnosis of the second stage of labor and delivery outcomes by Ashwal, Eran, Fan, Isabella Y., Berger, Howard, Livne, Michal Y., Hiersch, Liran, Aviram, Amir, Mani, Ariel, Yogev, Yariv

“…Controversy surrounds the impact of the fetal head station on labor duration and mode of delivery. Although an extensive body of evidence has been published…”
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Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells by Nham, Tina, Poznanski, Sophie M., Fan, Isabella Y., Shenouda, Mira M., Chew, Marianne V., Lee, Amanda J., Vahedi, Fatemeh, Karimi, Yalda, Butcher, Martin, Lee, Dean A., Hirte, Hal, Ashkar, Ali A.

“…Ovarian cancer (OC) is the leading cause of gynecological cancer-related death in North America. Most ovarian cancer patients (OCPs) experience disease…”
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Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells by Nham, Tina, Poznanski, Sophie M, Fan, Isabella Y, Vahedi, Fatemeh, Shenouda, Mira M, Lee, Amanda J, Chew, Marianne V, Hogg, Richard T, Lee, Dean A, Ashkar, Ali A

“…With over 600,000 units of umbilical cord blood (CB) stored on a global scale, it is important to elucidate the therapeutic abilities of this cryopreserved…”
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Abstract 2556: Expanded ovarian cancer patient NK cells represent a novel, cytotoxic phenotype and reduce autologous tumor in a patient-derived xenograft ovarian cancer model by Poznanski, Sophie M., Nham, Tina, Chew, Marianne V., Lee, Amanda J., Fan, Isabella Y., Lee, Dean A., Hirte, Hal, Ashkar, Ali A.

“…Abstract Introduction: Ex vivo expanded NK cells are emerging as a promising cancer immunotherapy and have recently shown clinical effectiveness in treating…”
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