Search Results - "Fan, Guangqin"

Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures by Zhou, Fankun, Yin, Guangming, Gao, Yanyan, Liu, Dong, Xie, Jie, Ouyang, Lu, Fan, Ying, Yu, Han, Zha, Zhipeng, Wang, Kai, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…•Early effects of Pb, Cd, and Hg mixtures were evaluated at low levels.•Metal mixtures (MM) caused multiple organ changes in morphology and function.•MM…”
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Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition by Ouyang, Lu, Li, Qi, Yang, Shuo, Yan, Lingyu, Li, Jiajun, Wan, Xin, Cheng, Hui, Li, Lingling, Liu, Peishan, Xie, Jie, Du, Guihua, Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…Lead (Pb), mercury (Hg), and cadmium (Cd) are prevalent and persistent environmental contaminants, causing detrimental effects on millions of individuals…”
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Assessing electrocardiogram changes after ischemic stroke with artificial intelligence by Zeng, Ziqiang, Wang, Qixuan, Yu, Yingjing, Zhang, Yichu, Chen, Qi, Lou, Weiming, Wang, Yuting, Yan, Lingyu, Cheng, Zujue, Xu, Lijun, Yi, Yingping, Fan, Guangqin, Deng, Libin

“…Ischemic stroke (IS) with subsequent cerebrocardiac syndrome (CCS) has a poor prognosis. We aimed to investigate electrocardiogram (ECG) changes after IS with…”
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Dietary, Nutrient Patterns and Blood Essential Elements in Chinese Children with ADHD by Zhou, Fankun, Wu, Fengyun, Zou, Shipu, Chen, Ying, Feng, Chang, Fan, Guangqin

“…Dietary or nutrient patterns represent the combined effects of foods or nutrients, and elucidate efficaciously the impact of diet on diseases. Because the…”
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Co-exposure to low-dose lead, cadmium, and mercury promotes memory deficits in rats: Insights from the dynamics of dendritic spine pruning in brain development by Zhou, Fankun, Ouyang, Lu, Xie, Jie, Liu, Sisi, Li, Qi, Yang, Shuo, Li, Jiajun, Su, Rui, Rao, Shaoqi, Yan, Lingyu, Wan, Xin, Cheng, Hui, Liu, Peishan, Li, Lingling, Zhu, Yanhui, Du, Guihua, Feng, Chang, Fan, Guangqin

“…Lead (Pb), cadmium (Cd), and mercury (Hg) are environmentally toxic heavy metals that can be simultaneously detected at low levels in the blood of the general…”
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dbMDEGA: a database for meta-analysis of differentially expressed genes in autism spectrum disorder by Zhang, Shuyun, Deng, Libin, Jia, Qiyue, Huang, Shaoting, Gu, Junwang, Zhou, Fankun, Gao, Meng, Sun, Xinyi, Feng, Chang, Fan, Guangqin

“…Autism spectrum disorders (ASD) are hereditary, heterogeneous and biologically complex neurodevelopmental disorders. Individual studies on gene expression in…”
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Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress by Huang, Ying, Yang, Wuping, Zeng, Huihong, Hu, Chuan, Zhang, Yaqiong, Ding, Nanhua, Fan, Guangqin, Shao, Lijian, Kuang, Bohai

“…Upregulation of histone acetylation plays a critical role in the dysregulation of transcription. It alters the structure of chromatin, which leads to the onset…”
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Transient Inhibition of mTORC1 Signaling Ameliorates Irradiation-Induced Liver Damage by Yang, Wuping, Shao, Lijian, Zhu, Sihong, Li, Huan, Zhang, Xinxin, Ding, Congcong, Wu, Xincheng, Xu, Rui, Yue, Mengzhen, Tang, Jiahui, Kuang, Bohai, Fan, Guangqin, Zhu, Qingxian, Zeng, Huihong

“…Recurrent liver cancer after surgery is often treated with radiotherapy, which induces liver damage. It has been documented that activation of the TGF-β and…”
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Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells by Shao, Lijian, Yang, Wuping, Xu, Rui, Zhu, Shuqin, Huang, Yanqiu, Li, Huan, Wu, Xincheng, Yue, Mengzhen, Xiong, Xiaoliang, Chen, Xiaowen, Kuang, Bohai, Fan, Guangqin, Zhu, Qingxian, Zeng, Huihong

“…Irradiation-induced kidney damage is inevitable during radiotherapeutic practice, which limits effective radiotherapy doses on tumor treatment. In the present…”
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The effect of the hemochromatosis (HFE) genotype on lead load and iron metabolism among lead smelter workers by Fan, Guangqin, Du, Guihua, Li, Huijun, Lin, Fen, Sun, Ziyong, Yang, Wei, Feng, Chang, Zhu, Gaochun, Li, Yanshu, Chen, Ying, Jiao, Huan, Zhou, Fankun

“…Both an excess of toxic lead (Pb) and an essential iron disorder have been implicated in many diseases and public health problems. Iron metabolism genes, such…”
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Lead-induced ER calcium release and inhibitory effects of methionine choline in cultured rat hippocampal neurons by Fan, Guangqin, Zhou, Fankun, Feng, Chang, Wu, Fengyun, Ye, Weiwei, Wang, Chunhong, Lin, Fen, Yan, Ji, Li, Yanshu, Chen, Ying, Bi, Yongyi

“…► The effects of Pb2+ on [Ca2+]i in cultured rat hippocampal neurons are examined. ► The antagonistic effects of methionine choline are investigated. ► Pb2+…”
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Methionine choline reverses lead-induced cognitive and N-methyl- d -aspartate receptor subunit 1 deficits by Fan, Guangqin, Feng, Chang, Wu, Fengyun, Ye, Weiwei, Lin, Fen, Wang, Chunhong, Yan, Ji, Zhu, Gaochun, Xiao, Yuanmei, Bi, Yongyi

“…Abstract The principal effects of Pb2+ exposure in children are attention, memory and learning deficits that persist into adulthood. The application of the…”
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The association between prenatal cadmium exposure and birth weight: A systematic review and meta-analysis of available evidence by Huang, Shouhe, Kuang, Jie, Zhou, Fankun, Jia, Qiyue, Lu, Qi, Feng, Chang, Yang, Wei, Fan, Guangqin

“…We conducted a meta-analysis to evaluate the association between prenatal cadmium (Cd) exposure and birth weight. PubMed, Embase, China National Knowledge…”
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Cognitive outcomes caused by low-level lead, cadmium, and mercury mixture exposure at distinct phases of brain development by Ouyang, Lu, Li, Qi, Rao, Shaoqi, Su, Rui, Zhu, Yanhui, Du, Guihua, Xie, Jie, Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…Contaminated water and food are the main sources of lead, cadmium, and mercury in the human body. Long-term and low-level ingestion of these toxic heavy metals…”
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Controlling lipid digestion profiles using mixtures of different types of microgel: Alginate beads and carrageenan beads by Chen, Fang, Deng, Zeyuan, Zhang, Zipei, Zhang, Ruojie, Xu, Qunying, Fan, Guangqin, Luo, Ting, McClements, David Julian

“…For certain applications, it is useful to control the rate and extent of lipid digestion in different regions of the gastrointestinal tract (GIT) e.g., to…”
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Insights into cognitive deficits caused by low-dose toxic heavy metal mixtures and their remediation through a postnatal enriched environment in rats by Zhou, Fankun, Yin, Guangming, Gao, Yanyan, Ouyang, Lu, Liu, Sisi, Jia, Qiyue, Yu, Han, Zha, Zhipeng, Wang, Kai, Xie, Jie, Fan, Ying, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…[Display omitted] •Metal mixtures (MM) caused cognitive deficits at human environmental exposure related levels.•MM induced cognitive deficits may be related…”
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Combined exposure of low dose lead, cadmium, arsenic, and mercury in mice by Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…•The study by Cobbina et al. published in Chemosphere in 2015 deserve critiques.•Levels of toxic metals measured in the control mice are extremely…”
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Toxic effects of combined exposure to four heavy metals at low doses by Fan, Guangqin, Zhou, Fankun, Feng, Chang

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RyRs mediate lead-induced neurodegenerative disorders through calcium signaling pathways by Zhou, Fankun, Du, Guihua, Xie, Jie, Gu, Junwang, Jia, Qiyue, Fan, Ying, Yu, Han, Zha, Zhipeng, Wang, Kai, Ouyang, Lu, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…[Display omitted] •Regulation of RyRs upon Pb exposure were studied in animal, tissue and cell models.•RyRs upregulation mediated Pb-induced neurodegenerative…”
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Lead, cadmium, arsenic, and mercury combined exposure disrupted synaptic homeostasis through activating the Snk-SPAR pathway by Zhou, Fankun, Xie, Jie, Zhang, Shuyun, Yin, Guangming, Gao, Yanyan, Zhang, Yuanyuan, Bo, Dandan, Li, Zongguang, Liu, Sisi, Feng, Chang, Fan, Guangqin

“…Lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) are among the leading toxic agents detected in the environment, and they have also been detected…”
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