Search Results - "Fan, CunYi"

Concentrically Integrative Bioassembly of a Three-Dimensional Black Phosphorus Nanoscaffold for Restoring Neurogenesis, Angiogenesis, and Immune Homeostasis by Qian, Yun, Yuan, Wei-En, Cheng, Yuan, Yang, Yunqi, Qu, Xinhua, Fan, Cunyi

“…Black phosphorus is well known for its excellent electromechanical properties. Although it has previously been used for therapeutic drug delivery in cancer, it…”
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Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice by Wang, Xiao, Li, Fengfeng, Xie, Liang, Crane, Janet, Zhen, Gehua, Mishina, Yuji, Deng, Ruoxian, Gao, Bo, Chen, Hao, Liu, Shen, Yang, Ping, Gao, Manman, Tu, Manli, Wang, Yiguo, Wan, Mei, Fan, Cunyi, Cao, Xu

“…Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by extraskeletal bone formation after injury. The exact pathogenesis…”
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Tendon healing and anti-adhesion properties of electrospun fibrous membranes containing bFGF loaded nanoparticles by Liu, Shen, Qin, Mingjie, Hu, Changmin, Wu, Fei, Cui, Wenguo, Jin, Tuo, Fan, Cunyi

“…Abstract The ideal scaffolds should contain growth factors and thus can regulate cellular behaviors and tissue assembly. Electrospun fibrous membranes are…”
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Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway by Cui, Haomin, He, Yu, Chen, Shuai, Zhang, Deming, Yu, Yaling, Fan, Cunyi

“…Following tendon injury, the development of fibrotic healing response impairs tendon function and restricts tendon motion. Peritendinous tissue fibrosis poses…”
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Aligned SF/P(LLA-CL)-blended nanofibers encapsulating nerve growth factor for peripheral nerve regeneration by Kuihua, Zhang, Chunyang, Wang, Cunyi, Fan, Xiumei, Mo

“…Artificial nerve guidance conduits (NGCs) containing bioactive neurotrophic factors and topographical structure to biomimic native tissues are essential for…”
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Polymeric Guide Conduits for Peripheral Nerve Tissue Engineering by Jiang, Huiquan, Qian, Yun, Fan, Cunyi, Ouyang, Yuanming

“…Peripheral nerve injuries (PNIs) are usually caused by trauma, immune diseases, and genetic factors. Peripheral nerve injury (PNI) may lead to limb numbness,…”
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Potential Value of miR-221/222 as Diagnostic, Prognostic, and Therapeutic Biomarkers for Diseases by Song, Jialin, Ouyang, Yuanming, Che, Junyi, Li, Xiaoming, Zhao, Yi, Yang, Kejia, Zhao, Xiaotian, Chen, Yinghui, Fan, Cunyi, Yuan, Weien

“…microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base pairing with their target messenger RNAs. Dysregulation of miRNAs is…”
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Insights into medical humanities education in China and the West by Qian, Yun, Han, Qixin, Yuan, Weien, Fan, Cunyi

“…Medical humanity is the soul of health education. Beginning medical students are taught various aspects of basic medicine, such as biochemistry, anatomy, and…”
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MicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling by Yao, Zhixiao, Li, Juehong, Xiong, Hao, Cui, Haomin, Ning, Jiexin, Wang, Shikun, Ouyang, Xingyu, Qian, Yun, Fan, Cunyi

“…Abstract Background Exosomes are extracellular vesicles of nano-structures and represent an emerging nano-scale acellular therapy in recent years. Tendon…”
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Preclinical assessment on neuronal regeneration in the injury-related microenvironment of graphene-based scaffolds by Qian, Yun, Wang, Xu, Song, Jialin, Chen, Wei, Chen, Shuai, Jin, Yi, Ouyang, Yuanming, Yuan, Wei-En, Fan, Cunyi

“…As the application of graphene nanomaterials gets increasingly attractive in the field of tissue engineering and regenerative medicine, the long-term…”
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Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult by Li, Juehong, Sun, Ziyang, Luo, Gang, Wang, Shuo, Cui, Haomin, Yao, Zhixiao, Xiong, Hao, He, Yunwei, Qian, Yun, Fan, Cunyi

“…Heterotopic ossification (HO) is one of the most intractable disorders following musculoskeletal injury and is characterized by the ectopic presence of bone…”
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Multilevel neurium-mimetic individualized graft via additive manufacturing for efficient tissue repair by Kong, Lingchi, Gao, Xin, Yao, Xiangyun, Xie, Haijiao, Kang, Qinglin, Sun, Wei, You, Zhengwei, Qian, Yun, Fan, Cunyi

“…Complicated peripheral nerve injuries or defects, especially at branching sites, remain a prominent clinical challenge after the application of different…”
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Advances in Roles of miR-132 in the Nervous System by Qian, Yun, Song, Jialin, Ouyang, Yuanming, Han, Qixin, Chen, Wei, Zhao, Xiaotian, Xie, Yangmei, Chen, Yinghui, Yuan, Weien, Fan, Cunyi

“…miR-132 is an endogenous small RNA and controls post-transcriptional regulation of gene expression via controlled degradation of mRNA or transcription…”
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Nerve Guidance Conduits from Aligned Nanofibers: Improvement of Nerve Regeneration through Longitudinal Nanogrooves on a Fiber Surface by Huang, Chen, Ouyang, Yuanming, Niu, Haitao, He, Nanfei, Ke, Qinfei, Jin, Xiangyu, Li, Dawei, Fang, Jun, Liu, Wanjun, Fan, Cunyi, Lin, Tong

“…A novel fibrous conduit consisting of well-aligned nanofibers with longitudinal nanogrooves on the fiber surface was prepared by electrospinning and was…”
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Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via PI3K/Akt signaling pathway by Wu, Ruoyu, Ruan, Jihao, Sun, Yongjin, Liu, Mengyu, Sha, Zhuang, Fan, Cunyi, Wu, Qingkai

“…This study was aimed to investigate the role and specific molecular mechanism of HIF1A-AS2/miR-665/IL6 axis in regulating osteogenic differentiation of…”
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Electrospun fibrous membranes featuring sustained release of ibuprofen reduce adhesion and improve neurological function following lumbar laminectomy by Liu, Shen, Pan, Guoqing, Liu, Guangwang, Neves, José das, Song, Sa, Chen, Shuai, Cheng, Bangjun, Sun, Zhiyong, Sarmento, Bruno, Cui, Wenguo, Fan, Cunyi

“…Electrospun fibrous membranes provide suitable physical anti-adhesion barriers for reducing tissue anti-adhesion following surgery. However, often during the…”
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Validation of the Liverpool Elbow Score for evaluation of elbow stiffness by Sun, Ziyang, Fan, Cunyi

“…The Liverpool Elbow Score (LES) has been widely used to assess the outcomes of total elbow replacement in various conditions. However, there have been no…”
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Overexpression of SOX9 alleviates the progression of human osteoarthritis in vitro and in vivo by Ouyang, Yuanming, Wang, Wei, Tu, Bing, Zhu, Yi, Fan, Cunyi, Li, Yanfeng

“…Recent findings have identified that SOX9 served as a key role during the pathogenesis of osteoarthritis (OA). This study aimed to investigate the mechanisms…”
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Multilayered spraying and gradient dotting of nanodiamond–polycaprolactone guidance channels for restoration of immune homeostasis by Qian, Yun, Cheng, Yuan, Ouyang, Yuanming, Yuan, Wei-En, Fan, Cunyi

“…The major problem in peripheral nerve repair is restoration of the microenvironment rather than traditional structural reconstruction. Nanodiamonds (NDs),…”
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Cell metabolism pathways involved in the pathophysiological changes of diabetic peripheral neuropathy by Lv, Yaowei, Yao, Xiangyun, Li, Xiao, Ouyang, Yuanming, Fan, Cunyi, Qian, Yun

“…[INLINE:1] Diabetic peripheral neuropathy is a common complication of diabetes mellitus. Elucidating the pathophysiological metabolic mechanism impels the…”
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