Search Results - "Famula, Thomas R."
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Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrating Hormone Receptor 2
Published in PLoS genetics (10-03-2022)“…Congenital idiopathic megaesophagus (CIM) is a gastrointestinal (GI) motility disorder of dogs in which reduced peristaltic activity and dilation of the…”
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Heritability and complex segregation analysis of naturally-occurring diabetes in Australian Terrier Dogs
Published in PloS one (24-09-2020)“…The Australian Terrier breed is the breed at highest risk for naturally-occurring diabetes mellitus in the United States, where it is 32 times more likely to…”
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Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995–2010)
Published in Journal of the American Veterinary Medical Association (01-06-2013)“…Objective-To determine the proportion of mixed-breed and purebred dogs with common genetic disorders. Design-Case-control study. Animals-27,254 dogs with an…”
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Genetic characterization of Addison's disease in Bearded Collies
Published in BMC genomics (26-11-2020)“…Primary hypoadrenocorticism (or Addison's disease, AD) is an autoimmune disease that results in destruction of the adrenal cortex and consequent adrenal…”
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Heritability and complex segregation analysis of diabetes mellitus in American Eskimo Dogs
Published in Journal of veterinary internal medicine (01-09-2019)“…Background Heritability and mode of inheritance of spontaneous diabetes mellitus (DM) in American Eskimo Dogs (AED) are unknown. Objective Investigate the…”
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Genome-Wide Association Studies Reveal Susceptibility Loci for Noninfectious Claw Lesions in Holstein Dairy Cattle
Published in Frontiers in genetics (28-05-2021)“…Sole ulcers (SUs) and white line disease (WLD) are two common noninfectious claw lesions (NICL) that arise due to a compromised horn production and are…”
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Pleiotropic Loci Associated With Foot Disorders and Common Periparturient Diseases in Holstein Cattle
Published in Frontiers in genetics (06-12-2021)“…Lameness is an animal welfare issue that incurs substantial financial and environmental costs. This condition is commonly caused by digital dermatitis (DD),…”
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Correction to: Genetic characterization of Addison's disease in Bearded Collies
Published in BMC genomics (30-12-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci
Published in PLoS genetics (03-02-2017)“…Juvenile dermatomyositis (JDM) is a chronic inflammatory myopathy and vasculopathy driven by genetic and environmental influences. Here, we investigated the…”
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A Review of the Impact of Neuter Status on Expression of Inherited Conditions in Dogs
Published in Frontiers in veterinary science (13-11-2019)“…Gonadectomy is an important reproductive management tool employed in many countries, and is highly prevalent in the US with an estimated 85% of dogs being…”
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QTL mapping of pomological traits in peach and related species breeding germplasm
Published in Molecular breeding (01-08-2015)“…Peach is an economically important fruit tree crop that exhibits high phenotypic variability yet suffers from diversity-limited gene pool. Genetic…”
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Evidence for a maternal origin of spontaneous autopolyploidy in cultured white sturgeon (Acipenser transmontanus)
Published in Aquaculture (01-01-2015)“…Sturgeons (order Acipenseriformes) are members of an ancient evolutionary lineage that has experienced multiple rounds of whole-genome duplication. As a…”
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And the beak shall inherit - evolution in response to invasion
Published in Ecology letters (01-09-2005)“…The increased demographic performance of biological invaders may often depend on their escape from specifically adapted enemies. Here we report that native…”
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Genome-Wide Association Studies Reveal Susceptibility Loci for Digital Dermatitis in Holstein Cattle
Published in Animals (Basel) (31-10-2020)“…Digital dermatitis (DD) causes lameness in dairy cattle. To detect the quantitative trait loci (QTL) associated with DD, genome-wide association studies (GWAS)…”
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Application of a Bayesian ordinal animal model for the estimation of breeding values for the resistance to Monilinia fruticola (G.Winter) Honey in progenies of peach [Prunus persica (L.) Batsch]
Published in Breeding Science (2017)“…Fruit brown rot caused by Monilinia spp. is the most important fungal disease of stone fruits worldwide. Several phenotyping protocols to accurately…”
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Heritability of Unilateral Elbow Dysplasia in the Dog: A Retrospective Study of Sire and Dam Influence
Published in Frontiers in veterinary science (22-11-2019)“…Canine elbow dysplasia is a significant health issue affecting many breeds. Unfortunately, treatments remain relatively limited, so control of this disease…”
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Evaluation of allele frequencies of inherited disease genes in subgroups of American Quarter Horses
Published in Journal of the American Veterinary Medical Association (2009)“…To estimate allele frequencies of the hyperkalaemic periodic paralysis (HYPP), lethal white foal syndrome (LWFS), glycogen branching enzyme deficiency (GBED),…”
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Heritability of lenticular myopia in English Springer spaniels
Published in Investigative ophthalmology & visual science (08-11-2013)“…We determined whether naturally-occurring lenticular myopia in English Springer spaniels (ESS) has a genetic component. Streak retinoscopy was performed on 226…”
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Inheritance of cerebellar abiotrophy in Arabians
Published in American journal of veterinary research (01-07-2011)“…Objective—To determine the mode of inheritance for cerebellar abiotrophy (CA), a neurologic disease in Arabians. Animals—804 Arabians, including 29 horses (15…”
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Early-emerging and highly heritable sensitivity to human communication in dogs
Published in Current biology (26-07-2021)“…Human cognition is believed to be unique in part because of early-emerging social skills for cooperative communication.1 Comparative studies show that at 2.5…”
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