Search Results - "Familiar, Olga"

Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone by Familiar, Olga, Munier-Lehmann, Hélène, Aínsa, José Antonio, Camarasa, María-José, Pérez-Pérez, María-Jesús

“…Thymidine monophosphate kinase from Mycobacterium tuberculosis (TMPKmt) has been proposed as an attractive target in the search of new agents to fight against…”
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From β-Amino-γ-sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral Activities by de Castro, Sonia, Familiar, Olga, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Camarasa, María-José, Velázquez, Sonsoles

“…Herein we describe the first successful application of the β‐amino‐γ‐sultone system as an intermediate for the synthesis of hitherto virtually unknown…”
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Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): Present and future by Pérez-Pérez, María-Jesús, Priego, Eva-María, Hernández, Ana-Isabel, Familiar, Olga, Camarasa, María-José, Negri, Ana, Gago, Federico, Balzarini, Jan

“…Human mitochondrial thymidine kinase (TK2) is a pyrimidine deoxynucleoside kinase (dNK) that catalyzes the phosphorylation of pyrimidine deoxynucleosides to…”
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Exploring Acyclic Nucleoside Analogues as Inhibitors of Mycobacterium tuberculosis Thymidylate Kinase by Familiar, Olga, Munier-Lehmann, Hélène, Negri, Ana, Gago, Federico, Douguet, Dominique, Rigouts, Leen, Hernández, Ana-Isabel, Camarasa, María-José, Pérez-Pérez, María-Jesús

“…In the search for novel inhibitors of the enzyme thymidine monophosphate kinase of Mycobacterium tuberculosis (TMPKmt), an attractive target for novel…”
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N -Substituted Thymine Derivatives as Mitochondrial Thymidine Kinase (TK-2) Inhibitors by Hernández, Ana-Isabel, Familiar, Olga, Negri, Ana, Rodríguez-Barrios, Fátima, Gago, Federico, Karlsson, Anna, Camarasa, María-José, Balzarini, Jan, Pérez-Pérez, María-Jesús

“…Novel N 1-substituted thymine derivatives related to 1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine have been synthesized and evaluated against thymidine…”
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N 1 -substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors by Hernandez, A-I, Familiar, O, Negri, A, Rodriguez-Barrios, F, Gago, F, Karlsson, A, Camarasa, M-J, Balzarini, J, Perez-Perez, M-J

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Synthesis of Enantiopure Planar Chiral Bisferrocenes Bearing Sulfur or Nitrogen Substituents by Arrayás, Ramón Gómez, Alonso, Inés, Familiar, Olga, Carretero, Juan Carlos

“…A new procedure for the preparation of enantiopure planar chiral bisferrocenes bearing potentially metal-coordinating sulfur or nitrogen substituents is…”
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N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors by HERNANDEZ, Ana-Isabel, FAMILIAR, Olga, NEGRI, Ana, RODRIGUEZ-BARRIOS, Fatima, GAGO, Federico, KARLSSON, Anna, CAMARASA, Maria-José, BALZARINI, Jan, PEREZ-PEREZ, Maria-Jesus

“…Novel N1-substituted thymine derivatives related to 1-[(Z)-4-(triphenylmethoxy)-2-butenyl]thymine have been synthesized and evaluated against thymidine…”
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Cationic Pd II Complexes of Fesulphos Ligands: Highly Efficient Catalysts for the Enantioselective Ring Opening of Oxa- and Azabicyclic Alkenes with Dialkylzinc Reagents by Cabrera, Silvia, Alonso, Inés, Arrayás, Ramón Gómez, Familiar, Olga, Carretero, Juan C.

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