Search Results - "Falzone, Nadia"

Targeted radionuclide therapy in combined-modality regimens by Gill, Martin R, Falzone, Nadia, Du, Yong, Vallis, Katherine A

“…Targeted radionuclide therapy (TRT) is a branch of cancer medicine concerned with the use of radioisotopes, radiolabelled molecules, nanoparticles, or…”
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Subcellular Targeting of Theranostic Radionuclides by Bavelaar, Bas M, Lee, Boon Q, Gill, Martin R, Falzone, Nadia, Vallis, Katherine A

“…The last decade has seen rapid growth in the use of theranostic radionuclides for the treatment and imaging of a wide range of cancers. Radionuclide therapy…”
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Targeted Radionuclide Therapy: New Advances for Improvement of Patient Management and Response by Malcolm, Javian, Falzone, Nadia, Lee, Boon Q, Vallis, Katherine A

“…Compared to external beam radiotherapy, targeted radionuclide therapy (TRT) allows for systemic radiation treatment of metastatic lesions. Published work on…”
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Deep Hybrid Learning Prediction of Patient-Specific Quality Assurance in Radiotherapy: Implementation in Clinical Routine by Moreau, Noémie, Bonnor, Laurine, Jaudet, Cyril, Lechippey, Laetitia, Falzone, Nadia, Batalla, Alain, Bertaut, Cindy, Corroyer-Dulmont, Aurélien

“…Arc therapy allows for better dose deposition conformation, but the radiotherapy plans (RT plans) are more complex, requiring patient-specific pre-treatment…”
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Radioimmunotherapy for Brain Metastases: The Potential for Inflammation as a Target of Choice by Corroyer-Dulmont, Aurélien, Jaudet, Cyril, Frelin, Anne-Marie, Fantin, Jade, Weyts, Kathleen, Vallis, Katherine A, Falzone, Nadia, Sibson, Nicola R, Chérel, Michel, Kraeber-Bodéré, Françoise, Batalla, Alain, Bardet, Stéphane, Bernaudin, Myriam, Valable, Samuel

“…Brain metastases (BM) are frequently detected during the follow-up of patients with malignant tumors, particularly in those with advanced disease. Despite a…”
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Impact of cyclic changes in pharmacokinetics and absorbed dose in pediatric neuroblastoma patients receiving [177Lu]Lu-DOTATATE by Malcolm, Javian C., Falzone, Nadia, Gains, Jennifer E., Aldridge, Matthew D., Mirando, David, Lee, Boon Q., Gaze, Mark N., Vallis, Katherine A.

“…Purpose Recent reports personalizing the administered activity (AA) of each cycle of peptide receptor radionuclide therapy based on the predicted absorbed dose…”
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An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse by Kersemans, Veerle, Beech, John S, Gilchrist, Stuart, Kinchesh, Paul, Allen, Philip D, Thompson, James, Gomes, Ana L, D'Costa, Zenobia, Bird, Luke, Tullis, Iain D C, Newman, Robert G, Corroyer-Dulmont, Aurelien, Falzone, Nadia, Azad, Abul, Vallis, Katherine A, Sansom, Owen J, Muschel, Ruth J, Vojnovic, Borivoj, Hill, Mark A, Fokas, Emmanouil, Smart, Sean C

“…Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was…”
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Stereotactic Inverse Dose Planning After Yttrium-90 Selective Internal Radiation Therapy in Hepatocellular Cancer by Abbott, Elliot, Young, Robert Steve, Hale, Caroline, Mitchell, Kimberly, Falzone, Nadia, Vallis, Katherine A., Kennedy, Andrew

“…Selective internal radiation therapy (SIRT) is administered to treat tumors of the liver and is generally well tolerated. Although widely adopted for its…”
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Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation by Kersemans, Veerle, Cornelissen, Bart, Hueting, Rebekka, Tredwell, Matthew, Hussien, Kamila, Allen, Philip D, Falzone, Nadia, Hill, Sally A, Dilworth, Jonathan R, Gouverneur, Veronique, Muschel, Ruth J, Smart, Sean C

“…Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly alter…”
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In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa by Falzone, Nadia, Huyser, Carin, Fourie, Francois, Toivo, Tim, Leszczynski, Dariusz, Franken, Daniel

“…Ejaculated, density purified, human spermatozoa were exposed to pulsed 900 MHz GSM mobile phone radiation at two specific absorption rate levels (SAR 2.0 and…”
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Individualized 131I-mIBG therapy in the management of refractory and relapsed neuroblastoma by George, Sally L, Falzone, Nadia, Chittenden, Sarah, Kirk, Stephanie J, Lancaster, Donna, Vaidya, Sucheta J, Mandeville, Henry, Saran, Frank, Pearson, Andrew D.J, Du, Yong, Meller, Simon T, Denis-Bacelar, Ana M, Flux, Glenn D

“…OBJECTIVEIodine-131-labelled meta-iodobenzylguanidine (I-mIBG) therapy is an established treatment modality for relapsed/refractory neuroblastoma, most…”
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EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer by Song, Lei, Falzone, Nadia, Vallis, Katherine A.

“…Purpose Radiolabeled antibodies and peptides hold promise for molecular radiotherapy but are often limited by a low payload resulting in inadequate delivery of…”
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Radiosensitization of CHO Cells by Two Novel Rhodium Complexes Under Oxic and Hypoxic Conditions by FALZONE, Nadia, BÖHM, Lothar, SWARTS, Jannie C, VAN RENSBURG, Constance E. J

“…Background: Tumour hypoxia severely limits the success of radiotherapy. Radiosensitization of hypoxic tumour cells by drugs is thus an important clinical…”
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First-Strike Rapid Predictive Dosimetry and Dose Response for 177Lu-PSMA Therapy in Metastatic Castration-Resistant Prostate Cancer by Kao, Yung Hsiang, Falzone, Nadia, Pearson, Michael, Sivaratnam, Dinesh

“…We devised and clinically validated a schema of rapid personalized predictive dosimetry for 177Lu-PSMA-I&T in metastatic castration-resistant prostate cancer…”
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First-Strike Rapid Predictive Dosimetry and Dose Response for 177 Lu-PSMA Therapy in Metastatic Castration-Resistant Prostate Cancer by Kao, Yung Hsiang, Falzone, Nadia, Pearson, Michael, Sivaratnam, Dinesh

“…We devised and clinically validated a schema of rapid personalized predictive dosimetry for Lu-PSMA-I&T in metastatic castration-resistant prostate cancer. It…”
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177Lu-PSMA With Olaparib Radiosensitization Potentiates Response and Toxicity in Extensive Castration-Resistant Metastatic Prostate cancer by Kao, Yung Hsiang, Falzone, Nadia, Pearson, Michael, Pook, David, Sivaratnam, Dinesh

“…Abstract A patient with widespread intensely prostate-specific membrane antigen–expressing, BRCA gene mutation–positive bone metastases at the time of prostate…”
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9th international symposium on physical, molecular, cellular, and medical aspects of Auger processes: preface by Vallis, Katherine A, Martin, Roger F., Falzone, Nadia

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OpenDose: Open-Access Resource for Nuclear Medicine Dosimetry by Chauvin, Maxime, Borys, Damian, Botta, Francesca, Bzowski, Pawel, Dabin, Jérémie, Denis-Bacelar, Ana M, Desbrée, Aurélie, Falzone, Nadia, Lee, Boon Quan, Mairani, Andrea, Malaroda, Alessandra, Mathieu, Gilles, McKay, Erin, Mora-Ramirez, Erick, Robinson, Andrew P, Sarrut, David, Struelens, Lara, Gil, Alex Vergara, Bardiès, Manuel

“…Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted…”
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Response to comment on "In vitro effect of pulsed 900 MHz GSM radiation on mitochondrial membrane potential and motility of human spermatozoa" by Falzone et al by Falzone, Nadia

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Monte Carlo Evaluation of Auger Electron-Emitting Theranostic Radionuclides by Falzone, Nadia, Fernández-Varea, José M, Flux, Glenn, Vallis, Katherine A

“…Several radionuclides used in medical imaging emit Auger electrons, which, depending on the targeting strategy, either may be exploited for therapeutic…”
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