Search Results - "Falvella, Felicia S."
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Transcription Deregulation at the 15q25 Locus in Association with Lung Adenocarcinoma Risk
Published in Clinical cancer research (01-03-2009)“…Purpose: We characterized the candidacy of the six candidate genes mapping in the chromosome 15q25 locus, which was previously reported as associated with lung…”
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Multiple Loci Modulate Opioid Therapy Response for Cancer Pain
Published in Clinical cancer research (01-07-2011)“…Patients treated with opioid drugs for cancer pain experience different relief responses, raising the possibility that genetic factors play a role in opioid…”
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A Comprehensive Appraisal of Laboratory Biochemistry Tests as Major Predictors of COVID-19 Severity
Published in Archives of pathology & laboratory medicine (1976) (01-12-2020)“…A relevant portion of coronavirus disease 2019 (COVID-19) patients develop severe disease with negative outcomes. Several biomarkers have been proposed to…”
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MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment
Published in Molecular cancer (17-03-2010)“…MFSD2A (major facilitator superfamily domain containing 2) gene maps on chromosome 1p34 within a linkage disequilibrium block containing genetic elements…”
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A 5'-region polymorphism modulates promoter activity of the tumor suppressor gene MFSD2A
Published in Molecular cancer (07-07-2011)“…The MFSD2A gene maps within a linkage disequilibrium block containing the MYCL1-EcoRI polymorphism associated with prognosis and survival in lung cancer…”
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Association of lung adenocarcinoma clinical stage with gene expression pattern in noninvolved lung tissue
Published in International journal of cancer (01-09-2012)“…Associations between clinical outcome of cancer patients and the gene expression signature in primary tumors at time of diagnosis have been reported. To test…”
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Eltrombopag-Induced Acute Liver Failure in a Pediatric Patient: A Pharmacokinetic and Pharmacogenetic Analysis
Published in Therapeutic drug monitoring (01-08-2018)“…Eltrombopag is an oral thrombopoietin receptor agonist approved for the treatment of patients with chronic idiopathic thrombocytopenic purpura (ITP), who are…”
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Pharmacokinetics and Pharmacogenetics of Selective Serotonin Reuptake Inhibitors During Pregnancy: An Observational Study
Published in Therapeutic drug monitoring (01-04-2017)“…An involvement of selective serotonin reuptake inhibitors (SSRIs) in increasing the risk of malformations, neonatal withdrawal syndrome, has been suggested…”
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Promoter Polymorphisms and Transcript Levels of Nicotinic Receptor CHRNA5
Published in JNCI : Journal of the National Cancer Institute (08-09-2010)“…Chromosomal locus 15q25, implicated in lung cancer risk and nicotine dependence, shows extensive linkage disequilibrium that complicates identification of…”
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Multiple isoforms and differential allelic expression of CHRNA5 in lung tissue and lung adenocarcinoma
Published in Carcinogenesis (New York) (01-06-2013)“…CHRNA5 gene expression variation may play a role in individual susceptibility to lung cancer. Analysis of CHRNA5 transcripts expressed in normal lung tissue…”
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The combination of pharmacogenetic and pharmacokinetic analyses to optimize clomipramine dosing in major depression: a case report
Published in Journal of clinical pharmacy and therapeutics (01-02-2017)“…Summary What is known and objective Polymorphisms in cytochrome P450 2D6 and 2C19 can lead to interindividual differences in drug plasma concentrations,…”
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LightSNiP assay is a good strategy for pharmacogenetics test
Published in Frontiers in pharmacology (02-06-2015)Get full text
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FGFR4 Gly388Arg polymorphism may affect the clinical stage of patients with lung cancer by modulating the transcriptional profile of normal lung
Published in International journal of cancer (15-06-2009)“…The association of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism with clinical stage and overall survival in a series of 541 Italian…”
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Multiple Genetic Loci Modulate Lung Adenocarcinoma Clinical Staging
Published in Clinical cancer research (15-04-2011)“…The main prognostic factor of lung cancer patient outcome is clinical stage, a parameter of tumor aggressiveness. Our study was conducted to test whether germ…”
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Genome-wide association study in discordant sibships identifies multiple inherited susceptibility alleles linked to lung cancer
Published in Carcinogenesis (New York) (01-03-2010)“…We analyzed a series of young (median age = 52 years) non-smoker lung cancer patients and their unaffected siblings as controls, using a genome-wide 620 901…”
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A polygenic model with common variants may predict lung adenocarcinoma risk in humans
Published in International journal of cancer (15-11-2008)“…Genome‐wide screening for genetic loci associated with risk of lung adenocarcinoma (ADCA) was carried out in pooled DNA using the Illumina 300K…”
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Reply to the Letter to the Editor from Wang
Published in Clinical cancer research (01-09-2009)Get full text
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MFSD2A is a novel lung tumour suppressor gene whose expression is modulated by a 5’-region polymorphism
Published in BMC proceedings (24-09-2010)Get full text
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The combination of pharmacogenetic and pharmacokinetic analyses to optimize clomipramine dosing in major depression: a case report
Published in Journal of clinical pharmacy and therapeutics (01-02-2017)“…WHAT IS KNOWN AND OBJECTIVEPolymorphisms in cytochrome P450 2D6 and 2C19 can lead to interindividual differences in drug plasma concentrations, affecting…”
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