Search Results - "Fallon, John F"

The dynamic spatial and temporal relationships between the phalanx‐forming region and the interdigits determine digit identity in the chick limb autopod by Suzuki, Takayuki, Fallon, John F.

“…Background Interdigits (IDs) determine digit identity in chick limbs. They are located between the digital rays and act as secondary signaling centers…”
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Downregulation of Grem1 expression in the distal limb mesoderm is a necessary precondition for phalanx development by Lancman, Joseph J., Hasso, Sean M., Suzuki, Takayuki, Kherdjemil, Yacine, Kmita, Marie, Ferris, Andrea, Dong, P. Duc S., Ros, Marian A., Fallon, John F.

“…Background The phalanges are the final skeletal elements to form in the vertebrate limb and their identity is regulated by signaling at the phalanx forming…”
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Unique SMAD1/5/8 activity at the phalanx-forming region determines digit identity by Suzuki, Takayuki, Hasso, Sean M, Fallon, John F

“…The zone of polarizing activity is the primary signaling center controlling anterior-posterior patterning of the amniote limb bud. The autopodial interdigits…”
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Molecular evidence for an activator-inhibitor mechanism in development of embryonic feather branching by Harris, M.P, Williamson, S, Fallon, J.F, Meinhardt, H, Prum, R.O

“…The developmental basis of morphological complexity remains a central question in developmental and evolutionary biology. Feathers provide a unique system to…”
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The evolution of HoxD-11 expression in the bird wing: insights from Alligator mississippiensis by Vargas, Alexander O, Kohlsdorf, Tiana, Fallon, John F, Vandenbrooks, John, Wagner, Günter P

“…Comparative morphology identifies the digits of the wing of birds as 1,2 and 3, but they develop at embryological positions that become digits 2, 3 and 4 in…”
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The Development of Archosaurian First-Generation Teeth in a Chicken Mutant by Harris, Matthew P., Hasso, Sean M., Ferguson, Mark W.J., Fallon, John F.

“…Modern birds do not have teeth. Rather, they develop a specialized keratinized structure, called the rhamphotheca, that covers the mandible, maxillae, and…”
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Regulation of Gremlin expression in the posterior limb bud by Nissim, Sahar, Hasso, Sean M., Fallon, John F., Tabin, Clifford J.

“…Proper outgrowth of the limb bud requires a positive feedback loop between Sonic hedgehog ( Shh) in the zone of polarizing activity (ZPA) and Fgfs in the…”
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Interdigital Regulation of Digit Identity and Homeotic Transformation by Modulated BMP Signaling by Dahn, Randall D., Fallon, John F.

“…The developmental mechanisms specifying digital identity have attracted 30 years of intense interest, but still remain poorly understood. Here, through…”
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Single base pair change in the long‐range Sonic hedgehog limb‐specific enhancer is a genetic basis for preaxial polydactyly by Maas, Sarah A., Fallon, John F.

“…In most instances of preaxial polydactyly (PPD), Sonic Hedgehog (Shh), an essential limb patterning signal, is ectopically expressed in an anterior region of…”
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Birds have dinosaur wings: The molecular evidence by Vargas, Alexander O., Fallon, John F.

“…Within developmental biology, the digits of the wing of birds are considered on embryological grounds to be digits 2, 3 and 4. In contrast, within…”
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The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb by Ros, Maria A, Dahn, Randall D, Fernandez-Teran, Marian, Rashka, Kay, Caruccio, Nicholas C, Hasso, Sean M, Bitgood, J James, Lancman, Joseph J, Fallon, John F

“…We have analyzed a new limb mutant in the chicken that we name oligozeugodactyly ( ozd ). The limbs of this mutant have a longitudinal postaxial defect,…”
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antiangiogenic neurokinin-B/thromboxane A2 regulatory axis by Pal, Saumen, Wu, Jing, Murray, Justin K, Gellman, Samuel H, Wozniak, Michele A, Keely, Patricia J, Boyer, Meghan E, Gomez, Timothy M, Hasso, Sean M, Fallon, John F, Bresnick, Emery H

“…Establishment of angiogenic circuits that orchestrate blood vessel development and remodeling requires an exquisite balance between the activities of pro- and…”
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Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formation by Sugi, Yukiko, Ito, Naoki, Szebenyi, Györgyi, Myers, Kioina, Fallon, John F, Mikawa, Takashi, Markwald, Roger R

“…While much has been learned about how endothelial cells transform to mesenchyme during cardiac cushion formation, there remain fundamental questions about the…”
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Analysis of the regulation of lin‐41 during chick and mouse limb development by Lancman, Joseph J., Caruccio, Nicholas C., Harfe, Brian D., Pasquinelli, Amy E., Schageman, Jeoffrey J., Pertsemlidis, Alexander, Fallon, John F.

“…We have cloned the chicken and mouse orthologues of the Caenorhabditis elegans heterochronic gene lin‐41. During limb development, lin‐41 is expressed in three…”
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Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation by Laufer, Ed, Dahn, Randall, Orozco, Olivia E, Yeo, Chang-Yeol, Pisenti, Jacqueline, Henrique, Domingos, Abbott, Ursula K, Fallon, John F, Tabin, Cliff

“…The apical ectodermal ridge of the vertebrate limb bud lies at the junction of the dorsal and ventral ectoderm and directs patterning of the growing limb. Its…”
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The digits of the wing of birds are 1, 2, and 3. a review by Vargas, Alexander O., Fallon, John F.

“…Fossil evidence documenting the evolutionary transition from theropod dinosaurs to birds indicates unambiguously that the digits of the wing of birds are…”
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Isolation of the chicken Lmbr1 coding sequence and characterization of its role during chick limb development by Maas, Sarah A., Fallon, John F.

“…In the developing amniote limb, anteroposterior (A/P) patterning is controlled through secretion of the Sonic Hedgehog (SHH) protein by cells in the zone of…”
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FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development by Fallon, John F., López, Alric, Ros, Maria A., Savage, Mary P., Olwin, Bradley B., Simandl, B. Kay

“…The apical ectodermal ridge permits growth and elongation of amniote limb buds; removal causes rapid changes in mesodermal gene expression, patterned cell…”
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Hedgehog-Regulated Processing of Gli3 Produces an Anterior/Posterior Repressor Gradient in the Developing Vertebrate Limb by Wang, Baolin, Fallon, John F, Beachy, Philip A

“…Ci/Gli zinc finger proteins mediate the transcriptional effects of Hedgehog protein signals. In Drosophila, Ci action as transcriptional repressor or activator…”
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Identification of spontaneous mutations within the long‐range limb‐specific Sonic hedgehog enhancer (ZRS) that alter Sonic hedgehog expression in the chicken limb mutants oligozeugodactyly and silkie breed by Maas, Sarah A., Suzuki, Takayuki, Fallon, John F.

“…The evolutionarily conserved, non‐coding ∼800‐base‐pair (bp) zone of polarizing activity (ZPA) regulatory sequence (ZRS) controls Shh expression in the…”
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