Search Results - "Faller, Elliott M."

IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein by Faller, Elliott M, McVey, Mark J, MacPherson, Paul A

“…Expression of the IL-7 receptor α-chain (CD127) is decreased on CD8 T-cells in HIV infected patients and partially recovers in those receiving antiretroviral…”
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MAP1a associated light chain 3 increases microtubule stability by suppressing microtubule dynamics by Faller, Elliott M., Villeneuve, Tania S., Brown, David L.

“…Microtubule associated proteins (MAP) have been shown to play a role in microtubule stability in axons and dendrites, in determining neuronal shape and in…”
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IL‐7 induces clathrin‐mediated endocytosis of CD127 and subsequent degradation by the proteasome in primary human CD8 T cells by Faller, Elliott M, Ghazawi, Feras M, Cavar, Marko, MacPherson, Paul A

“…Interleukin‐7 (IL‐7), a key immunoregulatory cytokine, plays an essential role in peripheral T‐cell homeostasis and function. Signaling via the IL‐7 receptor…”
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Suppressor of cytokine signaling (SOCS) proteins are induced by IL-7 and target surface CD127 protein for degradation in human CD8 T cells by Ghazawi, Feras M., Faller, Elliott M., Parmar, Parmvir, El-Salfiti, Abdulkareem, MacPherson, Paul A.

“…•IL-7 signaling plays key roles in the development and function of T cells.•SOCS proteins inhibit cytokine-induced signaling pathways in T cells.•IL-7 induces…”
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Transcriptional regulation of the IL-7Rα gene by dexamethasone and IL-7 in primary human CD8 T cells by Kakal, Juzer A., Ghazawi, Feras M., Faller, Elliott M., Sugden, Scott M., Parmar, Parmvir, MacPherson, Paul A.

“…Interleukin-7 is essential for the development and maintenance of T cells, and the expression of the IL-7 receptor is tightly regulated at every stage of the T…”
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IL‐7 downregulates IL‐7Rα expression in human CD8 T cells by two independent mechanisms by Ghazawi, Feras M, Faller, Elliott M, Sugden, Scott M, Kakal, Juzer A, MacPherson, Paul A

“…Interleukin (IL)‐7 is an essential nonredundant cytokine, and throughout the lifespan of a T‐cell signaling via the IL‐7 receptor influences cell survival,…”
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Soluble HIV Tat protein removes the IL-7 receptor alpha-chain from the surface of resting CD8 T cells and targets it for degradation by Faller, Elliott M, Sugden, Scott M, McVey, Mark J, Kakal, Juzer A, MacPherson, Paul A

“…IL-7 signaling is essential to CD8 T cell development, activation, and homeostasis. We have previously shown decreased expression of the IL-7R alpha-chain…”
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Modulation of microtubule dynamics by the microtubule-associated protein 1a by Faller, Elliott M., Brown, David L.

“…Structural microtubule‐associated proteins (MAPs) interact with microtubules to regulate the various dynamic stages of microtubules. The purpose of this study…”
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Interleukin-7 Receptor Expression on CD8 T-Cells Is Downregulated by the HIV Tat Protein by Faller, Elliott M, McVey, Mark J, Kakal, Juzer A, MacPherson, Paul A

“…We have previously shown decreased expression of the interleukin (IL)-7 receptor α-chain (CD127) on CD8 T-cells in HIV-infected patients and an apparent…”
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Transcriptional regulation of the IL-7R[alpha] gene by dexamethasone and IL-7 in primary human CD8 T cells by Kakal, Juzer A, Ghazawi, Feras M, Faller, Elliott M, Sugden, Scott M, Parmar, Parmvir, Macpherson, Paul A

“…Interleukin-7 is essential for the development and maintenance of T cells, and the expression of the IL-7 receptor is tightly regulated at every stage of the T…”
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IL-7 downregulates IL-7R[alpha] expression in human CD8 T cells by two independent mechanisms by Ghazawi, Feras M, Faller, Elliott M, Sugden, Scott M, Kakal, Juzer A, Macpherson, Paul A

“…Interleukin (IL)-7 is an essential nonredundant cytokine, and throughout the lifespan of a T-cell signaling via the IL-7 receptor influences cell survival,…”
Get full text