Search Results - "Falkowski, Sabrina"

Therapeutic Drug Monitoring of Everolimus in Oncology: Evidences and Perspectives by Falkowski, Sabrina, Woillard, Jean-Baptiste

“…Everolimus is a mammalian target of rapamycin (m-TOR) inhibitor that has been approved for the treatment of hormone receptor-positive advanced breast cancer,…”
Get full text

Effect of genetic polymorphisms in CYP3A4, CYP3A5, and m-TOR on everolimus blood exposure and clinical outcomes in cancer patients by Bonnet, Stéphanie, Falkowski, Sabrina, Deppenweiler, Marine, Monchaud, Caroline, Arnion, Hélène, Picard, Nicolas, Woillard, Jean-Baptiste

“…Genetic variations in CYP3A4, CYP3A5, and m-TOR could contribute to interpatient variability regarding m-TOR inhibitors pharmacokinetics or cellular effects…”
Get full text

Towards therapeutic drug monitoring of everolimus in cancer? Results of an exploratory study of exposure-effect relationship by Deppenweiler, Marine, Falkowski, Sabrina, Saint-Marcoux, Franck, Monchaud, Caroline, Picard, Nicolas, Laroche, Marie-Laure, Tubiana-Mathieu, Nicole, Venat-Bouvet, Laurence, Marquet, Pierre, Woillard, Jean-Baptiste

“…[Display omitted] Therapeutic drug monitoring (TDM) of everolimus is not performed in oncology and no trough level (C0) target has been yet defined. The aim of…”
Get full text

Common variants in glucuronidation enzymes and membrane transporters as potential risk factors for colorectal cancer: a case control study by Falkowski, Sabrina, Woillard, Jean-Baptiste, Postil, Deborah, Tubiana-Mathieu, Nicole, Terrebonne, Eric, Pariente, Antoine, Smith, Denis, Guimbaud, Rosine, Thalamas, Claire, Rouguieg-Malki, Koukeb, Marquet, Pierre, Picard, Nicolas

“…Associations between polymorphisms of UDP-glucuronosyltransferases (UGTs) or efflux transporters (e.g., P-glycoprotein and MRP2) and different types of cancer…”
Get full text

Résistance aux inhibiteurs des tyrosines kinases dans le cancer du rein by Falkowski, Sabrina

“…La dernière décennie a vu d’importantes avancées dans la compréhension de la biologie et de la génétique du cancer du rein, dont certaines ont modifié…”
Get full text

Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck squamous-cell carcinoma (GORTEC 2014-01 TPExtreme): a multicentre, open-label, randomised, phase 2 trial by Guigay, Joël, Fayette, Jérôme, Saada-Bouzid, Esma, Martin, Laurent, Capitain, Olivier, Castanie, Hélène, Vansteene, Damien, Schafhausen, Philippe, Johnson, Alison, Even, Caroline, Duplomb, Sophie, Evrard, Camille, Laguerre, Brigitte, Chevassus-Clément, Cécile, Sinigaglia, Laura, Keilholz, Ulrich, Bourhis, Jean, Mesia, Ricard, BABA-HAMED, Nabil, BABIN, Emmanuel, BERA, Guillaume, BETRIAN-LAGARDE, Sarah, BLOT, Emmanuel, BOREL, Christian, BRUYAS, Amandine, CALAIS, Gilles, CARPIUC, Ioana, CHAPET, Sophie, CHATELLIER, Thierry, CHELI, Sandrine, CLATOT, Florian, COJOCARASU, Oana, COUTTE, Alexandre, DALLOZ, Pierre, DELHOMMEAU, Melissa, DE RAUCOURT, Dominique, DEBOURDEAU, Philippe, DUBOS-ARVIS, Catherine, DUCOULOMBIER, Agnès, EL KOURI, Claude, FALKOWSKI, Sabrina, FERRAND, François-Regis, GATINEAU, Michel, GERVAIS, Radj, GRAS, Louis, HASBINI, Ali, HENAULT, Stéphane, HERRERA GOMEZ, Ruth Gabriela, HUGUET, Florence, LAGRANGE, Aurélie, LE FOLL, Christine, LINOT, Benjamin, LOPEZ, Qian, MAYACHE-BADIS, Lamia, MINNE, Floriane, NEIDHARDT, Eve Marie, PAVILLET, Julien, PEYRADE, Frédéric, POINTREAU, Yohann, RAMEE, Jean-François, RAUCHE, Camille, RICHARD, Sandrine, RIZZO, Claudia, ROLLAND, Frédéric, STEFANI, Laetitia, THERY, Jean-Christophe, TOULLEC, Clémence, TOURANI, Jean-Marc, TOUSSAINT, Philippe, VAULEON, Elodie, VIRET, Frédéric, WALER, Sabine, ATZPODIEN, Jens, FIETKAU, Rainer, GRANIZKA, Thordis, GUNTINAS-LICHINUS, Orlando, HADLER-MIKESCH, Kristina, HAHN, Dennis, INHESTERN, Johanna, KELLNER, Karolin, KLINGHAMMER, Konrad, KRONENBERGER, Roland, LUEDTKE-HECKENKAMP, Kerstin, PIRLICH, Markus, ROTHMANN, Frank, TOMETTEN, Mareike, WOHLFARTH, Sabine, ZEBRALLA, Veit, ZIPFEL, Matthias, ADANSA KLEIN, Juan Carlos, ARRAZUBI, Virginia, CABALLERO DAROQUI, Javier, CASTELO, Beatriz, GALLEGO, Oscar, IGLESIAS DOCAMPO, Lara Carmen, MARTINEZ DEL PRADO, Maria, MARTINEZ-TRUFERO, Javier, PASTOR BORGONON, Miguel, PEREZ RUIZ, Elisabeth, RUBIO CASADEVALL, Jordi

“…Results from a phase 2 trial of the TPEx chemotherapy regimen (docetaxel–platinum–cetuximab) showed promising results, with a median overall survival of 14·0…”
Get full text

CIMUC: Chemotherapy following Immune checkpoints inhibitors in patients with locally advanced or metastatic urothelial carcinoma (la/mUC) by Meynard, Lucie, Dinart, Derek, Flechon, Aude, Saldana, Carolina, Lefort, Felix, Gravis, Gwenaelle, Thiery-Vuillemin, Antoine, Cancel, Mathilde, Coquan, Elodie, Ladoire, Sylvain, Maillet, Denis, Rolland, Frederic, Boughalem, Elouen, Martin, Sophie, Laramas, Mathieu, Crouzet, Laurence, Abbar, Baptiste, Falkowski, Sabrina, Pouessel, Damien, Roubaud, Guilhem

“…Abstract only 492 Background: Immune checkpoints inhibitors (ICIs) have recently changed therapeutic landscape of la/mUC. Recent studies suggested an…”
Get full text

Chemotherapy following immune checkpoint inhibitors in patients with locally advanced or metastatic urothelial carcinoma by Meynard, Lucie, Dinart, Derek, Delaunay, Blandine, Fléchon, Aude, Saldana, Carolina, Lefort, Félix, Gravis, Gwenaëlle, Thiery-Vuillemin, Antoine, Cancel, Mathilde, Coquan, Elodie, Ladoire, Sylvain, Maillet, Denis, Rolland, Frédéric, Boughalem, Elouen, Martin, Sophie, Laramas, Mathieu, Crouzet, Laurence, Abbar, Baptiste, Falkowski, Sabrina, Pouessel, Damien, Roubaud, Guilhem

“…Recent studies suggest improvements in response to salvage chemotherapy (CT) after immune checkpoint inhibitors (ICIs) in several types of cancer. Our…”
Get full text

Chemotherapy following immune checkpoint inhibitors in patients with locally advanced or metastatic urothelial carcinoma by Meynard, Lucie, Dinart, Derek, Delaunay, Blandine, Fléchon, Aude, Saldana, Carolina, Lefort, Félix, Gravis, Gwenaëlle, Thiery-Vuillemin, Antoine, Cancel, Mathilde, Coquan, Elodie, Ladoire, Sylvain, Maillet, Denis, Rolland, Frédéric, Boughalem, Elouen, Martin, Sophie, Laramas, Mathieu, Crouzet, Laurence, Abbar, Baptiste, Falkowski, Sabrina, Pouessel, Damien, Roubaud, Guilhem

Get full text

First-Line Treatment of Metastatic Clear Cell Renal Cell Carcinoma: What Are the Most Appropriate Combination Therapies? by Vano, Yann-Alexandre, Ladoire, Sylvain, Elaidi, Réza, Dermeche, Slimane, Eymard, Jean-Christophe, Falkowski, Sabrina, Gross-Goupil, Marine, Malouf, Gabriel, Narciso, Bérangère, Sajous, Christophe, Tartas, Sophie, Voog, Eric, Ravaud, Alain

“…The development of antiangiogenic treatments, followed by immune checkpoint inhibitors (ICI), has significantly changed the management of metastatic clear cell…”
Get full text

Clinical activity of sunitinib rechallenge in metastatic renal cell carcinoma—Results of the REchallenge with SUnitinib in MEtastatic RCC (RESUME) Study by Oudard, Stéphane, Geoffrois, Lionnel, Guillot, Aline, Chevreau, Christine, Deville, Jean-Laurent, Falkowski, Sabrina, Boyle, Helen, Baciuchka, Marjorie, Gimel, Pierre, Laguerre, Brigitte, Laramas, Mathieu, Pfister, Christian, Topart, Delphine, Rolland, Frédéric, Legouffe, Eric, Denechere, Gwénaël, Amela, Eric Yaovi, Abadie-Lacourtoisie, Sophie, Gross-Goupil, Marine

“…Abstract Aim To assess the efficacy and tolerability of sunitinib rechallenge in the third-line or later setting in patients with metastatic renal cell…”
Get full text

Association of single nucleotide polymorphisms (SNPs) in CYP17A1 and SLCO2B1 genes and clinical outcome in metastatic castration-resistant prostate cancer patients treated with abiraterone acetate: results of the ABIGENE prospective study by Borchiellini, Delphine, Mahammedi, Hakim, Viotti, Julien, Gravis, Gwenaelle, Roubaud, Guilhem, Beuzeboc, Philippe, Largillier, Remy, Linassier, Claude, Khalil, Ahmed, Kaphan, Regis, Joly, Florence, Eymard, Jean-Christophe, Falkowski, Sabrina, Bompas, Emmanuelle, Zanetta, Sylvie, Schiappa, Renaud, Maurin, Maeva, Etienne-Grimaldi, Marie-Christine, Milano, Gerard A., Ferrero, Jean-Marc

“…Abstract only 358 Background: Abiraterone acetate (AA), a CYP17A1 inhibitor, has been approved in the treatment of metastatic castration-resistant prostate…”
Get full text

Radiodermatitis prevention with sucralfate in breast cancer: fundamental and clinical studies by Falkowski, Sabrina, Trouillas, Patrick, Duroux, Jean-Luc, Bonnetblanc, Jean-Marie, Clavère, Pierre

“…Background Acute radiodermatitis induced by radiotherapy may affect the quality of life and in some cases requires withholding treatment. The present study…”
Get full text

Représentations croisées sur l’alimentation et la dénutrition chez les patients atteints de cancer : résultats de l’étude NutriCancer2012 by Raynard, Bruno, Hébuterne, Xavier, Goldwasser, François, Ait Hssain, Ali, Dubray Longeras, Pascale, Barthélémy, Philippe, Rosso, Edoardo, Phoutthasang, Valérie, Bories, Camille, Digue, Laurence, Laharie, David, Desport, Jean-Claude, Falkowski, Sabrina, Lacau Saint Guily, Jean, Gyan, Emmanuel

“…La dénutrition est fréquente en cancérologie. Cependant, elle est souvent détectée tardivement et sa prise en charge n’est pas toujours optimale. L’avis du…”
Get full text