Search Results - "Falke, Sven"

Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract by Gevorgyan, Susanna, Schubert, Robin, Falke, Sven, Lorenzen, Kristina, Trchounian, Karen, Betzel, Christian

“…In recent years silver nanoparticles (Ag NPs) gained increased and widespread applications in various fields of industry, technology, and medicine. This study…”
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Characterization of Conjugates between α-Lactalbumin and Benzyl Isothiocyanate—Effects on Molecular Structure and Proteolytic Stability by Spöttel, Jenny, Brockelt, Johannes, Falke, Sven, Rohn, Sascha

“…In complex foods, bioactive secondary plant metabolites (SPM) can bind to food proteins. Especially when being covalently bound, such modifications can alter…”
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Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds by Alves França, Bruno, Falke, Sven, Rohde, Holger, Betzel, Christian

“…Bacterial caseinolytic protease P subunit (ClpP) is important and vital for cell survival and infectivity. Recent publications describe and discuss the complex…”
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Protein phase separation and determinants of in cell crystallization by Mudogo, Celestin N., Falke, Sven, Brognaro, Hévila, Duszenko, Michael, Betzel, Christian

“…Liquid‐liquid phase separation (LLPS) in cells is known as a complex physicochemical process causing the formation of membrane‐less organelles (MLOs). Cells…”
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The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity by Werner, Nadine, Petersen, Katrin, Vollstedt, Christel, Garcia, Pablo Perez, Chow, Jennifer, Ferrer, Manuel, Fernandez-Lopez, Laura, Falke, Sven, Perbandt, Markus, Hinrichs, Winfried, Betzel, Christian, Streit, Wolfgang R.

“…Previously, we reported the isolation of a quorum quenching protein (QQ), designated GqqA, from Komagataeibacter europaeus CECT 8546 that is highly homologous…”
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Structure and activity of the DHNA Coenzyme-A Thioesterase from Staphylococcus aureus providing insights for innovative drug development by Murad, Aline Melro, Brognaro, Hévila, Falke, Sven, Lindner, Jasmin, Perbandt, Markus, Mudogo, Celestin, Schubert, Robin, Wrenger, Carsten, Betzel, Christian

“…Humanity is facing an increasing health threat caused by a variety of multidrug resistant bacteria. Within this scenario, Staphylococcus aureus , in particular…”
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Eruca sativa seed napin structural insights and thorough functional characterization by Khaliq, Binish, Falke, Sven, Saeed, Qamar, Bilal, Muhammad, Munawar, Aisha, Ali, Arslan, Baermann, Gunnar, Athar, Habib-ur-Rehman, Mahmood, Seema, Betzel, Christian, Ali, Qurban, Akrem, Ahmed

“…A potent napin protein has been thoroughly characterized from seeds of rocket salad ( Eruca sativa ). Eruca sativa napin ( Es Nap) was purified by ammonium…”
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Structural and functional analysis of a plant nucleolar RNA chaperone-like protein by Fernandes, Rita, Ostendorp, Anna, Ostendorp, Steffen, Mehrmann, Judith, Falke, Sven, Graewert, Melissa Ann, Weingartner, Magdalena, Kehr, Julia, Hoth, Stefan

“…Ribosome biogenesis is a key process in all eukaryotic cells that requires hundreds of ribosome biogenesis factors (RBFs), which are essential to build the…”
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C‐phycocyanin as a highly attractive model system in protein crystallography: unique crystallization properties and packing‐diversity screening by Sarrou, Iosifina, Feiler, Christian G., Falke, Sven, Peard, Nolan, Yefanov, Oleksandr, Chapman, Henry

“…The unique crystallization properties of the antenna protein C‐phycocyanin (C‐PC) from the thermophilic cyanobacterium Thermosynechococcus elongatus are…”
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Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane by Knop, Jan, Lienemann, Tim, El-Kilani, Haifa, Falke, Sven, Krings, Catharina, Sindalovskaya, Maria, Bergler, Johannes, Betzel, Christian, Hoth, Stefan

“…Plant U-box armadillo repeat (PUB-ARM) ubiquitin (Ub) ligases have important functions in plant defense through the ubiquitination of target proteins. Defense…”
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Crystal structures of native cytochrome c6 from Thermosynechococcus elongatus in two different space groups and implications for its oligomerization by Falke, Sven, Feiler, Christian, Chapman, Henry, Sarrou, Iosifina

“…Native cytochrome c6 was purified from an extract of strain BP‐1 of the thermophilic cyanobacterium Thermosynechococcus elongatus. The protein was…”
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Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1-Pdx2 Complex by Ullah, Najeeb, Andaleeb, Hina, Mudogo, Celestin Nzanzu, Falke, Sven, Betzel, Christian, Wrenger, Carsten

“…species are protozoan parasites causing the deadly malaria disease. They have developed effective resistance mechanisms against most antimalarial medication,…”
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Tracing transport of protein aggregates in microgravity versus unit gravity crystallization by Martirosyan, Arayik, Falke, Sven, McCombs, Deborah, Cox, Martin, Radka, Christopher D., Knop, Jan, Betzel, Christian, DeLucas, Lawrence J.

“…Microgravity conditions have been used to improve protein crystallization from the early 1980s using advanced crystallization apparatuses and methods. Early…”
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A multi-channel in situ light scattering instrument utilized for monitoring protein aggregation and liquid dense cluster formation by Falke, Sven, Brognaro, Hévila, Martirosyan, Arayik, Dierks, Karsten, Betzel, Christian

“…Liquid-liquid phase separation (LLPS) phenomena have been observed in vitro as well as in vivo and came in focus of interdisciplinary research activities…”
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Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease by Ewert, Wiebke, Günther, Sebastian, Miglioli, Francesca, Falke, Sven, Reinke, Patrick Y A, Niebling, Stephan, Günther, Christian, Han, Huijong, Srinivasan, Vasundara, Brognaro, Hévila, Lieske, Julia, Lorenzen, Kristina, Garcia-Alai, Maria M, Betzel, Christian, Carcelli, Mauro, Hinrichs, Winfried, Rogolino, Dominga, Meents, Alke

“…The papain-like protease (PLpro) of SARS-CoV-2 is essential for viral propagation and, additionally, dysregulation of the host innate immune system. Using a…”
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Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections by Reinke, Patrick Y. A., de Souza, Edmarcia Elisa, Günther, Sebastian, Falke, Sven, Lieske, Julia, Ewert, Wiebke, Loboda, Jure, Herrmann, Alexander, Rahmani Mashhour, Aida, Karničar, Katarina, Usenik, Aleksandra, Lindič, Nataša, Sekirnik, Andreja, Botosso, Viviane Fongaro, Santelli, Gláucia Maria Machado, Kapronezai, Josana, de Araújo, Marcelo Valdemir, Silva-Pereira, Taiana Tainá, Filho, Antônio Francisco de Souza, Tavares, Mariana Silva, Flórez-Álvarez, Lizdany, de Oliveira, Danielle Bruna Leal, Durigon, Edison Luiz, Giaretta, Paula Roberta, Heinemann, Marcos Bryan, Hauser, Maurice, Seychell, Brandon, Böhler, Hendrik, Rut, Wioletta, Drag, Marcin, Beck, Tobias, Cox, Russell, Chapman, Henry N., Betzel, Christian, Brehm, Wolfgang, Hinrichs, Winfried, Ebert, Gregor, Latham, Sharissa L., Guimarães, Ana Marcia de Sá, Turk, Dusan, Wrenger, Carsten, Meents, Alke

“…Several drug screening campaigns identified Calpeptin as a drug candidate against SARS-CoV-2. Initially reported to target the viral main protease (M pro ),…”
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Crystal Structure of Mistletoe Lectin I (ML-I) from Viscum album in Complex with 4-N-Furfurylcytosine at 2.85 Å Resolution by Ahmad, Malik S, Rasheed, Saima, Falke, Sven, Khaliq, Binish, Perbandt, Markus, Choudhary, Muhammad I, Markiewicz, Wojciech T, Barciszewski, Jan, Betzel, Christian

“…Viscum album (the European mistletoe) is a semi-parasitic plant, which is of high medical interest. It is widely found in Europe, Asia, and North America. It…”
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Processing of the SARS-CoV pp1a/ab nsp7-10 region by Krichel, Boris, Falke, Sven, Hilgenfeld, Rolf, Redecke, Lars, Uetrecht, Charlotte

“…Severe acute respiratory syndrome coronavirus is the causative agent of a respiratory disease with a high case fatality rate. During the formation of the…”
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Highly affine and selective aptamers against cholera toxin as capture elements in magnetic bead-based sandwich ELAA by Frohnmeyer, Esther, Frisch, Farina, Falke, Sven, Betzel, Christian, Fischer, Markus

“…•ssDNA aptamers against cholera toxin were selected using the recently developed just in time-selection.•Dissociation constants in the low nanomolar range and…”
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Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2 by Oberthür, Dominik, Achenbach, John, Gabdulkhakov, Azat, Buchner, Klaus, Maasch, Christian, Falke, Sven, Rehders, Dirk, Klussmann, Sven, Betzel, Christian

“…We report the crystal structure of a 40mer mirror-image RNA oligonucleotide completely built from nucleotides of the non-natural L -chirality in complex with…”
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