Search Results - "Falk, Gary W."

Anti–Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis by Dellon, Evan S, Peterson, Kathryn A, Murray, Joseph A, Falk, Gary W, Gonsalves, Nirmala, Chehade, Mirna, Genta, Robert M, Leung, John, Khoury, Paneez, Klion, Amy D, Hazan, Sabine, Vaezi, Michael, Bledsoe, Adam C, Durrani, Sandy R, Wang, Chao, Shaw, Camilla, Chang, Alan T, Singh, Bhupinder, Kamboj, Amol P, Rasmussen, Henrik S, Rothenberg, Marc E, Hirano, Ikuo

“…Patients with eosinophilic gastritis, duodenitis, or both conditions were randomly assigned to receive placebo or AK002, an anti–Siglec-8 antibody that…”
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In vivo endomicroscopy improves detection of Barrett's esophagus–related neoplasia: a multicenter international randomized controlled trial (with video) by Canto, Marcia Irene, MD, MHS, Anandasabapathy, Sharmila, MD, Brugge, William, MD, Falk, Gary W., MD, Dunbar, Kerry B., MD, PhD, Zhang, Zhe, PhD, Woods, Kevin, MD, MPH, Almario, Jose Antonio, BS, MHS, Schell, Ursula, BS, Goldblum, John, MD, Maitra, Anirban, MD, Montgomery, Elizabeth, MD, Kiesslich, Ralf, MD, PhD

“…Background Confocal laser endomicroscopy (CLE) enables in vivo microscopic imaging of the GI tract mucosa. However, there are limited data on endoscope-based…”
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Increasing Rates of Diagnosis, Substantial Co-Occurrence, and Variable Treatment Patterns of Eosinophilic Gastritis, Gastroenteritis, and Colitis Based on 10-Year Data Across a Multicenter Consortium by Pesek, Robert D, Reed, Craig C, Muir, Amanda B, Fulkerson, Patricia C, Menard-Katcher, Calies, Falk, Gary W, Kuhl, Jonathan, Martin, Ellen K, Magier, Adam Z, Ahmed, Faria, Demarshall, Maureen, Gupta, Ankur, Gross, Jonathan, Ashorobi, Tokunbo, Carpenter, Christina L, Krischer, Jeffrey P, Gonsalves, Nirmala, Spergel, Jonathan M, Gupta, Sandeep K, Furuta, Glenn T, Rothenberg, Marc E, Dellon, Evan S

“…The literature related to eosinophilic gastritis (EG), gastroenteritis (EGE), and colitis (EC) is limited. We aimed to characterize rates of diagnosis,…”
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Notch Signaling Mediates Differentiation in Barrett’s Esophagus and Promotes Progression to Adenocarcinoma by Kunze, Bettina, Wein, Frederik, Fang, Hsin-Yu, Anand, Akanksha, Baumeister, Theresa, Strangmann, Julia, Gerland, Sophie, Ingermann, Jonas, Münch, Natasha Stephens, Wiethaler, Maria, Sahm, Vincenz, Hidalgo-Sastre, Ana, Lange, Sebastian, Lightdale, Charles J., Bokhari, Aqiba, Falk, Gary W., Friedman, Richard A., Ginsberg, Gregory G., Iyer, Prasad G., Jin, Zhezhen, Nakagawa, Hiroshi, Shawber, Carrie J., Nguyen, TheAnh, Raab, William J., Dalerba, Piero, Rustgi, Anil K., Sepulveda, Antonia R., Wang, Kenneth K., Schmid, Roland M., Wang, Timothy C., Abrams, Julian A., Quante, Michael

“…Studies are needed to determine the mechanism by which Barrett’s esophagus (BE) progresses to esophageal adenocarcinoma (EAC). Notch signaling maintains stem…”
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Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis by Noti, Mario, Wojno, Elia D Tait, Kim, Brian S, Siracusa, Mark C, Giacomin, Paul R, Nair, Meera G, Benitez, Alain J, Ruymann, Kathryn R, Muir, Amanda B, Hill, David A, Chikwava, Kudakwashe R, Moghaddam, Amin E, Sattentau, Quentin J, Alex, Aneesh, Zhou, Chao, Yearley, Jennifer H, Menard-Katcher, Paul, Kubo, Masato, Obata-Ninomiya, Kazushige, Karasuyama, Hajime, Comeau, Michael R, Brown-Whitehorn, Terri, de Waal Malefyt, Rene, Sleiman, Patrick M, Hakonarson, Hakon, Cianferoni, Antonella, Falk, Gary W, Wang, Mei-Lun, Spergel, Jonathan M, Artis, David

“…Eosinophilic esophagitis (EoE) is characterized by esophageal eosinophilia, but the underlying mechanisms promoting eosinophil accumulation remain unclear…”
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Virtual Dysphagia Evaluation: Practical Guidelines for Dysphagia Management in the Context of the COVID-19 Pandemic by Soldatova, Liuba, Williams, Colleen, Postma, Gregory N., Falk, Gary W., Mirza, Natasha

“…With encouraging signs of pandemic containment nationwide, the promise of return to a full range of clinical practice is on the horizon. Clinicians are…”
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ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus by Shaheen, Nicholas J, Falk, Gary W, Iyer, Prasad G, Gerson, Lauren B

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The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on imaging in Barrett's Esophagus by Sharma, Prateek, MD, Savides, Thomas J., MD, Canto, Marcia I., MD, MHS, Corley, Douglas A., MD, MPH, PhD, Falk, Gary W., MD, MS, Goldblum, John R., MD, Wang, Kenneth K., MD, Wallace, Michael B., MD, MPH, Wolfsen, Herbert C., MD

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Lower Annual Rate of Progression of Short-Segment vs Long-Segment Barrett’s Esophagus to Esophageal Adenocarcinoma by Hamade, Nour, Vennelaganti, Sreekar, Parasa, Sravanthi, Vennalaganti, Prashanth, Gaddam, Srinivas, Spaander, Manon C.W., van Olphen, Sophie H., Thota, Prashanthi N., Kennedy, Kevin F., Bruno, Marco J., Vargo, John J., Mathur, Sharad, Cash, Brooks D., Sampliner, Richard, Gupta, Neil, Falk, Gary W., Bansal, Ajay, Young, Patrick E., Lieberman, David A., Sharma, Prateek

“…European guidelines recommend different surveillance intervals of non-dysplastic Barrett’s esophagus (NDBE) based on segment length, as opposed to guidelines…”
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Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis by Rieder, Florian, Biancani, Piero, Harnett, Karen, Yerian, Lisa, Falk, Gary W

“…Gastroesophageal reflux disease (GERD) is one of the most common problems in clinical practice today. It is widely believed that functional and structural…”
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Patient-derived organoids as a platform for modeling a patient’s response to chemoradiotherapy in esophageal cancer by Karakasheva, Tatiana A., Gabre, Joel T., Sachdeva, Uma M., Cruz-Acuña, Ricardo, Lin, Eric W., DeMarshall, Maureen, Falk, Gary W., Ginsberg, Gregory G., Yang, Zhaohai, Kim, Michele M., Diffenderfer, Eric S., Pitarresi, Jason R., Li, Jinyang, Muir, Amanda B., Hamilton, Kathryn E., Nakagawa, Hiroshi, Bass, Adam J., Rustgi, Anil K.

“…3D patient-derived organoids (PDOs) have been utilized to evaluate potential therapies for patients with different cancers. However, the use of PDOs created…”
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Association Between Length of Barrett's Esophagus and Risk of High-grade Dysplasia or Adenocarcinoma in Patients Without Dysplasia by Anaparthy, Rajeswari, Gaddam, Srinivas, Kanakadandi, Vijay, Alsop, Benjamin R, Gupta, Neil, Higbee, April D, Wani, Sachin B, Singh, Mandeep, Rastogi, Amit, Bansal, Ajay, Cash, Brooks D, Young, Patrick E, Lieberman, David A, Falk, Gary W, Vargo, John J, Thota, Prashanti, Sampliner, Richard E, Sharma, Prateek

“…Background & Aims It is not clear whether length of Barrett's esophagus (BE) is a risk factor for high-grade dysplasia (HGD) or esophageal adenocarcinoma (EAC)…”
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Eosinophilic Esophagitis: A Review by Muir, Amanda, Falk, Gary W

“…IMPORTANCE: Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory disease of the esophagus that affects an estimated 34.4/100 000 people in…”
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The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on peroral endoscopic myotomy by Chandrasekhara, Vinay, MD, Desilets, David, MD, PhD, Falk, Gary W., MD, MS, Inoue, Haruhiro, MD, PhD, Romanelli, John R., MD, Savides, Thomas J., MD, Stavropoulos, Stavros N., MD, Swanstrom, Lee L., MD

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Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration by Gupta, Sandeep K., Falk, Gary W., Aceves, Seema S., Chehade, Mirna, Collins, Margaret H., Dellon, Evan S., Gonsalves, Nirmala, Hirano, Ikuo, Mukkuda, Vincent A., Peterson, Kathryn A., Spergel, Jonathan, Yang, Guang-Yu, Furuta, Glenn T., Rothenberg, Marc E.

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Increasing prevalence of high-grade dysplasia and adenocarcinoma on index endoscopy in Barrett’s esophagus over the past 2 decades: data from a multicenter U.S. consortium by Desai, Madhav, Lieberman, David A., Kennedy, Kevin F., Hamade, Nour, Thota, Prashanthi, Parasa, Sravanthi, Gorrepati, Venkat Subhash, Bansal, Ajay, Gupta, Neil, Gaddam, Srinivas, Young, Patrick E., Mathur, Sharad, Moawad, Fouad J., Cash, Brooks D., Sampliner, Richard, Vargo, John J., Falk, Gary W., Sharma, Prateek

“…Data on time trends of dysplasia and esophageal adenocarcinoma (EAC) in Barrett’s esophagus (BE) during the index endoscopy (ie, prevalent cases) are limited…”
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High Patient Disease Burden in a Cross‐sectional, Multicenter Contact Registry Study of Eosinophilic Gastrointestinal Diseases by Jensen, Elizabeth T., Aceves, Seema S., Bonis, Peter A., Bray, Kimberly, Book, Wendy, Chehade, Mirna, Collins, Margaret H., Dellon, Evan S., Falk, Gary W., Gonsalves, Nirmala, Gupta, Sandeep K., Hirano, Ikuo, Katzka, David A., Kyle, Shay, Mack, Denise, Kodroff, Ellyn, Leung, John, Mukkada, Vincent A., Scott, Melissa, Paliana, Ally, Sable, Kathleen, Spergel, Jonathan M., Strobel, Mary Jo, Krischer, Jeffrey, Rothenberg, Marc E., Abonia, Pablo

“…ABSTRACT Objectives: Clinical features of eosinophilic esophagitis (EoE) have been well‐described in the literature, however, characterization of features…”
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Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis by Whelan, Kelly A, Merves, Jamie F, Giroux, Veronique, Tanaka, Koji, Guo, Andy, Chandramouleeswaran, Prasanna M, Benitez, Alain J, Dods, Kara, Que, Jianwen, Masterson, Joanne C, Fernando, Shahan D, Godwin, Bridget C, Klein-Szanto, Andres J, Chikwava, Kudakwashe, Ruchelli, Eduardo D, Hamilton, Kathryn E, Muir, Amanda B, Wang, Mei-Lun, Furuta, Glenn T, Falk, Gary W, Spergel, Jonathan M, Nakagawa, Hiroshi

“…The influence of eosinophilic oesophagitis (EoE)-associated inflammation upon oesophageal epithelial biology remains poorly understood. We investigated the…”
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Barrett's oesophagus: Frequency and prediction of dysplasia and cancer by Falk, Gary W., M.D., M.S

“…Abstract The incidence of oesophageal adenocarcinoma is continuing to increase at an alarming rate in the Western world today. Barrett's oesophagus is a…”
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An open-label, prospective trial of cryospray ablation for Barrett's esophagus high-grade dysplasia and early esophageal cancer in high-risk patients by Dumot, John A., DO, Vargo, John J., MD, MPH, Falk, Gary W., MD, MHS, Frey, Lorraine, RN, BSN, Lopez, Rocio, MS, Rice, Thomas W., MD

“…Background Endoscopic ablation of Barrett's esophagus (BE) is a treatment option for patients with high-grade dysplasia (HGD) and intramucosal carcinoma…”
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