Search Results - "Falk, Christine Susanne"

PI3K/AKT/mTOR‐dependent stabilization of oncogenic far‐upstream element binding proteins in hepatocellular carcinoma cells by Samarin, Jana, Laketa, Vibor, Malz, Mona, Roessler, Stephanie, Stein, Ilan, Horwitz, Elad, Singer, Stephan, Dimou, Eleni, Cigliano, Antonio, Bissinger, Michaela, Falk, Christine Susanne, Chen, Xin, Dooley, Steven, Pikarsky, Eli, Calvisi, Diego Francesco, Schultz, Carsten, Schirmacher, Peter, Breuhahn, Kai

“…Transcription factors of the far‐upstream element‐binding protein (FBP) family represent cellular pathway hubs, and their overexpression in liver cancer…”
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CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis by Lauruschkat, Chris David, Muchsin, Ihsan, Rein, Alice, Erhard, Florian, Grathwohl, Denise, Dölken, Lars, Köchel, Carolin, Falk, Christine Susanne, Einsele, Hermann, Wurster, Sebastian, Grigoleit, Götz Ulrich, Kraus, Sabrina

“…Human cytomegalovirus (HCMV) causes significant morbidity and mortality in allogeneic stem cell transplant (alloSCT) recipients. Recently, antiviral letermovir…”
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HCC Immune Surveillance and Antiviral Therapy of Hepatitis C Virus Infection by Owusu Sekyere, Solomon, Schlevogt, Bernhard, Mettke, Friederike, Kabbani, Mohammad, Deterding, Katja, Wirth, Thomas Christian, Vogel, Arndt, Manns, Michael Peter, Falk, Christine Susanne, Cornberg, Markus, Wedemeyer, Heiner

“…Objective: HCV clearance by current antiviral therapies improves clinical outcomes but falls short in eliminating the risk for hepatocellular carcinoma (HCC)…”
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Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury by Blume, Cornelia, Felix, Agnieszka, Shushakova, Nelli, Gueler, Faikah, Falk, Christine Susanne, Haller, Hermann, Schrader, Juergen

“…Extracellular adenosine formed by 5'-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important…”
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Induction of Stress-Induced Renal Cellular Senescence In Vitro: Impact of Mouse Strain Genetic Diversity by Liao, Chieh Ming, Wulfmeyer, Vera Christine, Swallow, Maxine, Falk, Christine Susanne, Haller, Hermann, Korstanje, Ron, Melk, Anette, Schmitt, Roland

“…Cellular senescence, a stress-induced state of irreversible cell cycle arrest, is associated with organ dysfunction and age-related disease. While immortalized…”
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Type I Interferon Elevates Co-Regulatory Receptor Expression on CMV- and EBV-Specific CD8 T Cells in Chronic Hepatitis C by Owusu Sekyere, Solomon, Suneetha, Pothakamuri Venkata, Hardtke, Svenja, Falk, Christine Susanne, Hengst, Julia, Manns, Michael Peter, Cornberg, Markus, Wedemeyer, Heiner, Schlaphoff, Verena

“…Hepatitis C virus (HCV) readily sets up persistence in a large fraction of infected hosts. Mounting epidemiological and immunological evidence suggest that…”
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Direct-Acting Antiviral–Induced Hepatitis C Virus Clearance Does Not Completely Restore the Altered Cytokine and Chemokine Milieu in Patients With Chronic Hepatitis C by Hengst, Julia, Falk, Christine Susanne, Schlaphoff, Verena, Deterding, Katja, Manns, Michael Peter, Cornberg, Markus, Wedemeyer, Heiner

“…Background. Persistent infection with hepatitis C virus (HCV) causes profound alterations of the cytokine and chemokine milieu in peripheral blood. However, it…”
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Systemic inflammation and immune cell phenotypes are associated with neuro‐psychiatric symptoms in patients with chronic inflammatory liver diseases by Aregay, Amare, Dirks, Meike, Schlaphoff, Verena, Owusu Sekyere, Solomon, Haag, Kim, Falk, Christine Susanne, Hengst, Julia, Bremer, Birgit, Schuppner, Ramona, Manns, Michael P., Pflugrad, Henning, Cornberg, Markus, Wedemeyer, Heiner, Weissenborn, Karin

“…Background & Aims Chronic inflammatory liver diseases are frequently associated with neuropsychiatric and cognitive dysfunctions. We hypothesized that…”
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Impaired T cells and “memory-like” NK-cell reconstitution is linked to late-onset HCMV reactivation after letermovir cessation by Lauruschkat, Chris David, Muchsin, Ihsan, Rein, Alice Felicitas, Erhard, Florian, Grathwohl, Denise, Dölken, Lars, Köchel, Carolin, Nehmer, Anne, Falk, Christine Susanne, Grigoleit, Götz Ulrich, Einsele, Hermann, Wurster, Sebastian, Kraus, Sabrina

“…•Clinically significant HCMV reactivation after letermovir cessation is associated with both T-cell and “memory-like” NK-cell impairments.•HCMV manifestation…”
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Identification of miR‐126 as a new regulator of skin ageing by Fiedler, Jan, Grönniger, Elke, Pfanne, Angelika, Brönneke, Simone, Schmidt, Katrin, Falk, Christine Susanne, Wenck, Horst, Terstegen, Lara, Thum, Thomas, Winnefeld, Marc

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Renal phenotype of young and old telomerase-deficient mice by Schildhorn, Carolin, Jacobi, Christoph, Weißbrodt, Andrea, Hermstedt, Christine, Westhoff, Jens Hendrik, Hömme, Meike, Bhayadia, Raj, Gretz, Norbert, Falk, Christine Susanne, Schmitt, Roland, Bröcker, Verena, Kränzlin, Bettina, Melk, Anette

“…•The hallmark of human renal ageing phenotype is its impaired ability to regenerate.•Young late generation Terc−/− mice show mild functional and histological…”
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