Changes in the Retina in Induced Hypoestrogenia (According to Optical Coherent Tomography Data)

Changes in the Retina in Induced Hypoestrogenia (According to Optical Coherent Tomography Data)

Ultrastructural changes in the retina under conditions of experimental hypoestrogenia were studied. Hypoestrogenic status was induced in female rabbits by extirpation of both uterine horns with appendages. Clinical status of the eyes was evaluated after 9 months by ophthalmoscopy and optical coheren...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine Vol. 155; no. 5; pp. 680 - 681
Main Authors: Obrubov, A.S., Obrubov, S. A., Medvedev, I. B., Dreval, A. A., Maximova, N. V., Falhut, O. S.
Format: Journal Article
Language:English
Published: Boston Springer US 01-09-2013
Springer
Springer Nature B.V
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Choroid - metabolism
Choroid - pathology
Estradiol - blood
Estradiol - deficiency
Female
Hysterectomy
Internal Medicine
Laboratory Medicine
Ophthalmoscopy
Optic Nerve - metabolism
Optic Nerve - pathology
Pathology
Progesterone - blood
Progesterone - deficiency
Rabbits
Retinal Pigment Epithelium - metabolism
Retinal Pigment Epithelium - pathology
Tomography
Tomography, Optical Coherence
experimental hypoestrogenia
retina
optical coherent tomography
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Summary:Ultrastructural changes in the retina under conditions of experimental hypoestrogenia were studied. Hypoestrogenic status was induced in female rabbits by extirpation of both uterine horns with appendages. Clinical status of the eyes was evaluated after 9 months by ophthalmoscopy and optical coherent tomography. Changes in the retinal layers under conditions of experimental estrogenia were detected: thickened retinal pigmented epithelium layer, a lesser layer of nerve fibrils, and thinning of the choriocapillary layer. A relationship between thinning of the choroid and thickening of the pigmented epithelium of the retina was detected.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-013-2224-z