Search Results - "Falconer, I R"

Oral toxicity of the cyanobacterial toxin cylindrospermopsin in male Swiss albino mice: Determination of no observed adverse effect level for deriving a drinking water guideline value by Humpage, A. R., Falconer, I. R.

“…The cyanobacterial toxin cylindrospermopsin (CYN) is a frequent contaminant of freshwaters throughout the world, including those that are sources of drinking…”
Get full text

Interaction of the cyanobacterial toxin cylindrospermopsin with the eukaryotic protein synthesis system by Froscio, S.M., Humpage, A.R., Wickramasinghe, W., Shaw, G., Falconer, I.R.

“…The cyanobacterial toxin cylindrospermospin (CYN) was shown to inhibit the eukaryotic protein synthesis apparatus with similar potency in plant and mammalian…”
Get full text

The cyanobacterial toxin, cylindrospermopsin, induces fetal toxicity in the mouse after exposure late in gestation by Rogers, E.H., Zehr, R.D., Gage, M.I., Humpage, A.R., Falconer, I.R., Marr, M., Chernoff, N.

“…Cylindrospermopsin (cyn) is a cyanobacterial toxin implicated in human and wildlife poisonings. We have completed studies investigating the potential of…”
Get full text

Preliminary evidence for in vivo tumour initiation by oral administration of extracts of the blue-green alga Cylindrospermopsis raciborskii containing the toxin cylindrospermopsin by Falconer, I. R., Humpage, A. R.

“…New reports indicate that the toxic alkaloid cylindrospermopsin occurs in cyanobacteria in Israel, Florida, South America, and Australia in drinking water…”
Get full text

Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake by Hawkins, Peter R., Chandrasena, Nimal R., Jones, Gary J., Humpage, Andrew R., Falconer, Ian R.

“…In Australia, the tropical/ subtropical cyanobacterium Cylindrospermopsis raciborskii forms substantial blooms in some drinking water supply reservoirs, rivers…”
Get full text

Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir by HAWKINS, P. R, RUNNEGAR, M. T. C, JACKSON, A. R. B, FALCONER, I. R

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Cytoskeletal changes in hepatocytes induced by Microcystis toxins and their relation to hyperphosphorylation of cell proteins by Falconer, I R, Yeung, D S

“…The heptapeptide toxins produced by the blue-green alga (cyanobacterium) Microcystis aeruginosa are selectively hepatotoxic in mammals. The characteristic…”
Get more information

Cyanobacterial toxins present in Microcystis aeruginosa extracts—More than microcystins by Falconer, Ian R.

Get full text

Effect of the cyanobacterial (blue-green algal) toxins from Microcystis aeruginosa on isolated enterocytes from the chicken small intestine by Falconer, I R, Dornbusch, M, Moran, G, Yeung, S K

“…Livestock deaths, and clinical reports of human injury, follow the consumption of toxic blue-green algae. The experiments described show that isolated…”
Get more information

Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin by Humpage, Andrew R, Fenech, Michael, Thomas, Philip, Falconer, Ian R

“…Cylindrospermopsin (CYN) is a potent inhibitor of protein synthesis produced by a number of cyanobacterial species, the most common being Cylindrospermopsis…”
Get full text

HEALTH RISKS CAUSED BY FRESHWATER CYANOBACTERIA IN RECREATIONAL WATERS by Ingrid Chorus, Ian R. Falconer, Henry J. Salas, Jamie Bartram

“…Toxic cyanobacteria are increasingly being perceived as a potential health hazard, particularly in waters used for recreation. A few countries are developing…”
Get full text

The uptake of the cyanobacterial hepatotoxin microcystin by isolated rat hepatocytes by Runnegar, M T, Gerdes, R G, Falconer, I R

“…Microcystin-YM a cyclic heptapeptide hepatotoxin isolated from the cyanobacterium Microcystis aeruginosa was radiolabeled with 125I, and used to investigate…”
Get more information

Tumour promotion by Microcystis sp., a blue-green alga occurring in water supplies by Falconer, I R, Buckley, T H

Get more information

Effect of toxin from the cyanobacterium Microcystis aeruginosa on ultrastructural morphology and actin polymerization in isolated hepatocytes by Runnegar, M T, Falconer, I R

“…Freshly isolated rat hepatocytes incubated with the hepatotoxin from the cyanobacterium Microcystis aeruginosa are rapidly deformed (blebbed). Transmission…”
Get more information

Evidence of liver damage by toxin from a bloom of the blue-green alga, Microcystis aeruginosa by Falconer, I R, Beresford, A M, Runnegar, M T

“…Examination of the results of routine assays for hepatic enzymes in plasma has shown a significant elevation of the levels of gamma-glutamyl-transpeptidase,…”
Get more information

MICROCYSTINS (CYANOBACTERIAL TOXINS) IN DRINKING WATER ENHANCE THE GROWTH OF ABERRANT CRYPT FOCI IN THE MOUSE COLON by Humpage, A R, Hardy, S J, Moore, E J, Froscio, S M, Falconer, I R

“…Microcystis aeruginosa produces toxic cyclic peptides called microcystins, potent hepatotoxins that have been implicated in tumor promotion in skin and liver…”
Get full text

Using Activated Carbon to Remove Toxicity From Drinking Water Containing Cyanobacterial Blooms by Falconer, Ian R., Runnegar, Maria T.C., Buckley, Tom, Van L. Huyn, Bradshaw, Peter

“…Toxic blooms of cyanobacteria, including Anabaena species, which are neurotoxic, and Microcystis, which is hepatotoxic, are becoming increasingly common in…”
Get full text

Cell-free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin by Froscio, Suzanne M., Humpage, Andrew R., Burcham, Philip C., Falconer, Ian R.

“…The cyanobacterial toxin cylindrospermopsin (CYN) is known to be a potent inhibitor of protein synthesis. This paper describes the use of a rabbit reticulocyte…”
Get full text

Injury to hepatocytes induced by a peptide toxin from the cyanobacterium Microcystis aeruginosa by Runnegar, M T, Andrews, J, Gerdes, R G, Falconer, I R

“…The freshwater, bloom forming cyanobacterium (blue-green alga) Microcystis aeruginosa produces a peptide hepatotoxin which causes death accompanied by liver…”
Get more information

Toxicity of the cyanobacterium Nodularia spumigena Mertens by Runnegar, M T, Jackson, A R, Falconer, I R

“…The bloom forming cyanobacterium (blue-green alga) Nodularia spumigena produced a peptide hepatotoxin with an LD50 of 70 micrograms/kg i.p. in mice. The livers…”
Get more information