Search Results - "Falcicchia, Chiara"

Involvement of p38 MAPK in Synaptic Function and Dysfunction by Falcicchia, Chiara, Tozzi, Francesca, Arancio, Ottavio, Watterson, Daniel Martin, Origlia, Nicola

“…Many studies have revealed a central role of p38 MAPK in neuronal plasticity and the regulation of long-term changes in synaptic efficacy, such as long-term…”
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T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex by Tozzi, Francesca, Rutigliano, Grazia, Borsò, Marco, Falcicchia, Chiara, Zucchi, Riccardo, Origlia, Nicola

“…Abnormalities in thyroid hormones (TH) availability and/or metabolism have been hypothesized to contribute to Alzheimer's disease (AD) and to be a risk factor…”
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Non-Canonical Roles of Tau and Their Contribution to Synaptic Dysfunction by Siano, Giacomo, Falcicchia, Chiara, Origlia, Nicola, Cattaneo, Antonino, Di Primio, Cristina

“…Tau plays a central role in a group of neurodegenerative disorders collectively named tauopathies. Despite the wide range of diverse symptoms at the onset and…”
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Lack of Direct Effects of Neurotrophic Factors in an In Vitro Model of Neuroinflammation by Aziz, Nimra, Ruzza, Chiara, Falcicchia, Chiara, Guarino, Annunziata, Soukupova, Marie, Asth, Laila, Aleotti, Valentina, Bettegazzi, Barbara, Simonato, Michele, Zucchini, Silvia

“…Neuroinflammation is associated with several neurological disorders including temporal lobe epilepsy. Seizures themselves can induce neuroinflammation. In an…”
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Smell and Taste in Severe CoViD-19: Self-Reported vs. Testing by Mazzatenta, Andrea, Neri, Giampiero, D'Ardes, Damiano, De Luca, Carlo, Marinari, Stefano, Porreca, Ettore, Cipollone, Francesco, Vecchiet, Jacopo, Falcicchia, Chiara, Panichi, Vincenzo, Origlia, Nicola, Di Giulio, Camillo

“…One of the most striking reported symptoms in CoViD-19 is loss of smell and taste. The frequency of these impairments and their specificity as a potential…”
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New Tools for Epilepsy Therapy by Falcicchia, Chiara, Simonato, Michele, Verlengia, Gianluca

“…One third of the epilepsies are refractory to conventional antiepileptic drugs (AEDs) and, therefore, identification of new therapies is highly needed. Here,…”
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Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy by Falcicchia, Chiara, Paolone, Giovanna, Emerich, Dwaine F, Lovisari, Francesca, Bell, William J, Fradet, Tracie, Wahlberg, Lars U, Simonato, Michele

“…Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its…”
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Corrigendum: New Tools for Epilepsy Therapy by Falcicchia, Chiara, Simonato, Michele, Verlengia, Gianluca

“…[This corrects the article DOI: 10.3389/fncel.2018.00147.]…”
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Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors by Falcicchia, Chiara, Trempat, Pascal, Binaschi, Anna, Perrier-Biollay, Coline, Roncon, Paolo, Soukupova, Marie, Berthommé, Hervé, Simonato, Michele

“…Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be…”
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Loss of cortical GABA terminals in Unverricht–Lundborg disease by Buzzi, Andrea, Chikhladze, Maia, Falcicchia, Chiara, Paradiso, Beatrice, Lanza, Giovanni, Soukupova, Marie, Marti, Matteo, Morari, Michele, Franceschetti, Silvana, Simonato, Michele

“…Abstract Unverricht–Lundborg disease (ULD) is the most common progressive myoclonic epilepsy. Its etiology has been identified in a defect of a protease…”
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Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer's disease by Gabrielli, Martina, Prada, Ilaria, Joshi, Pooja, Falcicchia, Chiara, D'Arrigo, Giulia, Rutigliano, Grazia, Battocchio, Elisabetta, Zenatelli, Rossella, Tozzi, Francesca, Radeghieri, Annalisa, Arancio, Ottavio, Origlia, Nicola, Verderio, Claudia

“…Synaptic dysfunction is an early mechanism in Alzheimer's disease that involves progressively larger areas of the brain over time. However, how it starts and…”
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Anti-epileptogenic effect of NRP2945 in the pilocarpine model of temporal lobe epilepsy by Lovisari, Francesca, Guarino, Annunziata, Soukupova, Marie, Falcicchia, Chiara, Ingusci, Selene, Marino, Pietro, Thomas, Mark, Sieg, Frank, Simonato, Michele

“…Innovative therapeutic strategies are highly needed to tackle the major medical needs of epilepsy, like prevention of epilepsy development in at-risk…”
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Role of extracellular vesicles in early synaptic dysfunction in AD by Gabrielli, Martina, D'Arrigo, Giulia, Falcicchia, Chiara, Origlia, Nicola, Arancio, Ottavio, Verderio, Claudia, Prada, Ilaria

“…Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder associated with amyloid‐β (Aβ) and tau protein accumulation. Synaptic…”
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MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples by Roncon, Paolo, Soukupovà, Marie, Binaschi, Anna, Falcicchia, Chiara, Zucchini, Silvia, Ferracin, Manuela, Langley, Sarah R., Petretto, Enrico, Johnson, Michael R., Marucci, Gianluca, Michelucci, Roberto, Rubboli, Guido, Simonato, Michele

“…The identification of biomarkers of the transformation of normal to epileptic tissue would help to stratify patients at risk of epilepsy following brain injury…”
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Long-Term, Targeted Delivery of GDNF from Encapsulated Cells Is Neuroprotective and Reduces Seizures in the Pilocarpine Model of Epilepsy by Paolone, Giovanna, Falcicchia, Chiara, Lovisari, Francesca, Kokaia, Merab, Bell, William J, Fradet, Tracie, Barbieri, Mario, Wahlberg, Lars U, Emerich, Dwaine F, Simonato, Michele

“…Neurotrophic factors are candidates for treating epilepsy, but their development has been hampered by difficulties in achieving stable and targeted delivery of…”
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Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy by Soukupová, Marie, Binaschi, Anna, Falcicchia, Chiara, Zucchini, Silvia, Roncon, Paolo, Palma, Eleonora, Magri, Eros, Grandi, Enrico, Simonato, Michele

“…The alterations in GABA release have not yet been systematically measured along the natural course of temporal lobe epilepsy. In this work, we analyzed GABA…”
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Role of microglial extracellular vesicles in the propagation of early synaptic dysfunction in Alzheimer’s disease by Gabrielli, Martina, Tozzi, Francesca, Falcicchia, Chiara, D'Arrigo, Giulia, Amoretti, Stefano, Joshi, Pooja, Tonoli, Elisa, Rutigliano, Grazia, Masini, Greta, Nardi, Gabriele, Battocchio, Elisabetta, Zenatelli, Rossella, Radeghieri, Annalisa, Verderio‐Edwards, Elisabetta, Ratto, Gianmichele, Arancio, Ottavio, Prada, Ilaria, Origlia, Nicola, Verderio, Claudia

“…Background Synaptic dysfunction is an early mechanism in Alzheimer’s disease (AD) which involves progressively larger areas of the brain over time. However,…”
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Role of extracellular vesicles in early synaptic dysfunction in AD by Prada, Ilaria, Gabrielli, Martina, Joshi, Pooja, Falcicchia, Chiara, D'Arrigo, Giulia, Rutigliano, Grazia, Tonoli, Elisa, Battocchio, Elisabetta, Zenatelli, Rossella, Tozzi, Francesca, Verderio‐Edwards, Elisabetta, Radeghieri, Annalisa, Arancio, Ottavio, Origlia, Nicola, Verderio, Claudia

“…Background Synaptic dysfunction is an early mechanism in Alzheimer’s Disease (AD) which involves progressively larger areas of the brain over time. However,…”
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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats by Soukupová, Marie, Falcicchia, Chiara, Lovisari, Francesca, Ingusci, Selene, Barbieri, Mario, Zucchini, Silvia, Simonato, Michele

“…Microdialysis is a well-established neuroscience technique that correlates the changes of neurologically active substances diffusing into the brain…”
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Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats by Soukupová, Marie, Falcicchia, Chiara, Lovisari, Francesca, Ingusci, Selene, Barbieri, Mario, Zucchini, Silvia, Simonato, Michele

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