Search Results - "Falci, Diego"

Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab by Gupta, Anil, Gonzalez-Rojas, Yaneicy, Juarez, Erick, Crespo Casal, Manuel, Moya, Jaynier, Falci, Diego R, Sarkis, Elias, Solis, Joel, Zheng, Hanzhe, Scott, Nicola, Cathcart, Andrea L, Hebner, Christy M, Sager, Jennifer, Mogalian, Erik, Tipple, Craig, Peppercorn, Amanda, Alexander, Elizabeth, Pang, Phillip S, Free, Almena, Brinson, Cynthia, Aldinger, Melissa, Shapiro, Adrienne E

“…In this ongoing, randomized, phase 3 trial, sotrovimab (a SARS-CoV-2–targeted monoclonal antibody) or placebo was administered to outpatients within 5 days…”
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Neglected endemic mycoses by Queiroz-Telles, Flavio, Fahal, Ahmed Hassan, Falci, Diego R, Caceres, Diego H, Chiller, Tom, Pasqualotto, Alessandro C

“…Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections…”
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Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens by Sandri, Ana M., Landersdorfer, Cornelia B., Jacob, Jovan, Boniatti, Márcio M., Dalarosa, Micheline G., Falci, Diego R., Behle, Tainá F., Bordinhão, Rosaura C., Wang, Jiping, Forrest, Alan, Nation, Roger L., Li, Jian, Zavascki, Alexandre P.

“…Background. Polymyxin B is a last-line therapy for multidrug-resistant gram-negative bacteria. There is a dearth of pharmacokinetic data to guide dosing in…”
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Effect of Sotrovimab on Hospitalization or Death Among High-risk Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial by Gupta, Anil, Gonzalez-Rojas, Yaneicy, Juarez, Erick, Crespo Casal, Manuel, Moya, Jaynier, Rodrigues Falci, Diego, Sarkis, Elias, Solis, Joel, Zheng, Hanzhe, Scott, Nicola, Cathcart, Andrea L, Parra, Sergio, Sager, Jennifer E, Austin, Daren, Peppercorn, Amanda, Alexander, Elizabeth, Yeh, Wendy W, Brinson, Cynthia, Aldinger, Melissa, Shapiro, Adrienne E

“…IMPORTANCE: Older patients and those with comorbidities who are infected with SARS-CoV-2 may be at increased risk of hospitalization and death. Sotrovimab is a…”
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Clinical mycology in Latin America and the Caribbean: A snapshot of diagnostic and therapeutic capabilities by Falci, Diego R., Pasqualotto, Alessandro C.

“…Summary Despite the existence of endemic mycoses in Latin America and the Caribbean, in addition to a large population of patients at risk for invasive…”
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Polymyxin Acute Kidney Injury: Dosing and Other Strategies to Reduce Toxicity by Nation, Roger L, Rigatto, Maria Helena P, Falci, Diego R, Zavascki, Alexandre P

“…Polymyxins are valuable antimicrobials for the management of multidrug-resistant Gram-negative bacteria; however, nephrotoxicity associated with these drugs is…”
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Clinical Characteristics of Covid-19 in China by Zavascki, Alexandre P, Falci, Diego R, Chen, Andre T.C, Coura-Filho, George B, Rehder, Marília H.H, Rolf, J. Douglass, Henry, Brandon M, Vikse, Jens, Guan, Wei-jie, Zhong, Nan-shan

“…To the Editor: According to the World Health Organization (WHO), the case definition for surveillance of returning travelers requires that they need to present…”
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Single-Dose Amphotericin B for Cryptococcal Meningitis by Falci, Diego R., Pasqualotto, Alessandro C., Lawrence, David S., Harrison, Thomas S., Jarvis, Joseph N.

“…To the Editor: Jarvis et al. (March 24 issue) 1 showed that a regimen that included a single dose of liposomal amphotericin B (10 mg per kilogram of body…”
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Severe Infusion-Related Adverse Events and Renal Failure in Patients Receiving High-Dose Intravenous Polymyxin B by John, Josiane F, Falci, Diego R, Rigatto, Maria Helena, Oliveira, Renata D, Kremer, Thaysa G, Zavascki, Alexandre P

“…The use of very high doses of polymyxin B (PMB) against carbapenem-resistant Gram-negative bacilli has been addressed in experiments as a strategy to improve…”
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Multicenter Prospective Cohort Study of Renal Failure in Patients Treated with Colistin versus Polymyxin B by Rigatto, Maria Helena, Oliveira, Maura S, Perdigão-Neto, Lauro V, Levin, Anna S, Carrilho, Claudia M, Tanita, Marcos Toshiyuki, Tuon, Felipe F, Cardoso, Douglas E, Lopes, Natane T, Falci, Diego R, Zavascki, Alexandre P

“…Nephrotoxicity is the main adverse effect of colistin and polymyxin B (PMB). It is not clear whether these two antibiotics are associated with different…”
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Profile of isavuconazole and its potential in the treatment of severe invasive fungal infections by Falci, Diego R, Pasqualotto, Alessandro C

“…The triazole class of antifungal drugs comprises first-line agents for the treatment of several invasive fungal diseases. Isavuconazole is a novel…”
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Incidence of histoplasmosis in patients receiving TNF-alpha inhibitors: A systematic review and meta-analysis by Cipolat, Murillo M, Rodrigues, Débora R R, Brenol, Claiton V, Pasqualotto, Alessandro C, Falci, Diego R

“…Immunobiological drugs such as TNF-α inhibitors are valuable in rescue therapy for autoimmune diseases such as rheumatoid arthritis and inflammatory bowel…”
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Early antiretroviral therapy for HIV-infected patients admitted to an intensive care unit (EARTH-ICU): A randomized clinical trial by Boniatti, Márcio M, Pellegrini, José Augusto S, Marques, Leonardo S, John, Josiane F, Marin, Luiz G, Maito, Lina R. D. M, Lisboa, Thiago C, Damiani, Lucas P, Falci, Diego R, Dal Pizzol, Felipe

“…Background Highly active antiretroviral therapy (HAART) has reduced HIV-related morbidity and mortality at all stages of infection and reduced transmission of…”
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Risk factors for acute kidney injury (AKI) in patients treated with polymyxin B and influence of AKI on mortality: a multicentre prospective cohort study by Rigatto, Maria Helena, Behle, Tainá F, Falci, Diego R, Freitas, Thiela, Lopes, Natane T, Nunes, Mariá, Costa, Leonardo W, Zavascki, Alexandre P

“…The objectives of this study were to assess risk factors for acute kidney injury (AKI) in patients treated with polymyxin B, a last resort antibiotic against…”
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Single High Dose of Liposomal Amphotericin B in Human Immunodeficiency Virus/AIDS-Related Disseminated Histoplasmosis: A Randomized Trial by Pasqualotto, Alessandro C, Lana, Daiane Dalla, Godoy, Cassia S M, Leitão, Terezinha do Menino Jesus Silva, Bay, Monica B, Damasceno, Lisandra Serra, Soares, Renata B A, Kist, Roger, Silva, Larissa R, Wiltgen, Denusa, Melo, Marineide, Guimarães, Taiguara F, Guimarães, Marilia R, Vechi, Hareton T, de Mesquita, Jacó R L, Monteiro, Gloria Regina de G, Adenis, Antoine, Bahr, Nathan C, Spec, Andrej, Boulware, David R, Israelski, Dennis, Chiller, Tom, Falci, Diego R

“…Abstract Background Histoplasmosis is a major AIDS-defining illness in Latin America. Liposomal amphotericin B (L-AmB) is the drug of choice for treatment, but…”
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In vitro activity of ceftaroline against bacterial isolates causing skin and soft tissue and respiratory tract infections collected in Latin American countries, ATLAS program 2016–2020 by Mohamed, Naglaa, Valdez, Rafael Ricardo, Fandiño, Cecil, Baudrit, Monique, Falci, Diego R., Murillo, Jorge Damián Chaverri

“…•Strong activity for ceftaroline against MRSA (MIC90 1–2 mg/L) from SSTIs and RTIs.•Higher susceptibility to ceftaroline for MRSA from SSTIs versus RTIs (92.5%…”
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Impact of polymyxin-B-associated acute kidney injury in 1-year mortality and renal function recovery by Gomes, Eduardo C., Falci, Diego R., Bergo, Pedro, Zavascki, Alexandre P., Rigatto, Maria Helena

“…•46.1% of patients who survived the first 30 days after PMB died within 1 year.•Renal failure and dialyses during PMB therapy were related to 1-year…”
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Comparison of nephrotoxicity associated to different lipid formulations of amphotericin B: a real-life study by Falci, Diego R., da Rosa, Franciane B., Pasqualotto, Alessandro C.

“…Summary Amphotericin B (AmB) use is limited by the occurrence of kidney toxicity. Here, we evaluated the incidence and impact of nephrotoxicity in a large…”
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The current state of Clinical Mycology in Eastern and South-Eastern Europe by Driemeyer, Cândida, Falci, Diego R, Hoenigl, Martin, Cornely, Oliver A, Chakrabarti, Arunaloke, Gangneux, Jean Pierre, Segal, Esther, Jürna-Ellam, Marika, Matos, Tadeja, Meis, Jacques F, Perfect, John R, Arsenijevic, Valentina Arsic, Mares, Mihai, Serban, Daniela Elena, Pasqualotto, Alessandro C

“…Abstract The ability of medical centers in Eastern and South-Eastern Europe to diagnose and treat fungal infections remains unknown. In order to investigate…”
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Hematological toxicities associated with amphotericin B formulations by Falci, Diego R, da Rosa, Franciane B, Pasqualotto, Alessandro C

“…Even though amphotericin B is associated with considerable hematological toxicity, this subject has been poorly studied. This retrospective cohort study…”
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