Search Results - "Falceto‐Font, Laura"
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S163: POLYSOME INTERACTOME IN RPS14‐DEFICIENT CELLS REVEALS THE INVOLVEMENT OF THE MRNA DECAY MACHINERY IN TRANSLATION SELECTIVITY
Published in HemaSphere (08-08-2023)Get full text
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A summer course in cancer for high school students-an update on lessons taught and lessons learned
Published in BMC medical education (17-09-2024)“…Previous graduate students and postdoctoral associates from the University of Florida Health Cancer Center, in partnership with the University of Florida…”
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Immunotherapy reverses glioma-driven dysfunction of immune system homeostasis
Published in Journal for immunotherapy of cancer (01-02-2023)“…BackgroundGlioma-induced immune dysregulation of the hematopoietic system has been described in a limited number of studies. In this study, our group further…”
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In Vivo Mouse Models for Adult Brain Tumors: Exploring Tumorigenesis and Advancing Immunotherapy Development
Published in Neuro-oncology (Charlottesville, Va.) (04-11-2024)“…Brain tumors, particularly glioblastoma (GBM), are devastating and challenging to treat, with a low 5-year survival rate of only 6.6%. Mouse models are…”
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TMIC-61. INVESTIGATING REPROGRAMING OF THE GBM’S TUMOR MICROENVIRONMENT AS A RESULT OF CO-TRANSFER OF HEMATOPOIETIC STEM CELLS (HSCS) WITH ADOPTIVE CELLULAR THERAPY
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)“…Glioblastoma (GBM) is an incredibly aggressive and prevalent primary CNS tumor with dismal survival outcomes. GBM’s intra-tumor heterogeneity and the powerful…”
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IMMU-14. SINGLE CELL RNASEQ OF PBMCS FROM NEWLY-DIAGNOSED GLIOBLASTOMA PATIENTS
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)Get full text
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Elucidating the cellular mechanisms underlying adoptive cell transfer in models of glioma
Published in The Journal of immunology (1950) (01-05-2023)“…Despite advances in solid tumor biology and oncology, pediatric and adult primary brain cancer and metastasis to the brain harbor dismal prognosis and poor…”
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TAMI-78. STEM CELL IMMUNOTHERAPY MODULATES IMMUNOREGULATORY PATHWAYS IN THE TUMOR MICROENVIRONMENT
Published in Neuro-oncology (Charlottesville, Va.) (12-11-2021)Get full text
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TMIC-13. GLIOMA-DRIVEN DENDRITIC CELL DYSFUNCTION AS AN IMMUNE EVASION STRATEGY AGAINST ADOPTIVE CELLULAR THERAPY
Published in Neuro-oncology (Charlottesville, Va.) (14-11-2022)Get full text
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IMMU-36. PD-1KO HEMATOPOIETIC STEM CELLS RAPIDLY DIFFERENTIATE INTO GLIOMA-INFILTRATING EFFECTOR T-CELLS
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)Get full text
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EXTH-11. ADOPTIVE CELLULAR THERAPY OVERCOMES GLIOMA IMMUNE ESCAPE BY DISRUPTING MDSC PROLIFERATION AND RECRUITMENT
Published in Neuro-oncology (Charlottesville, Va.) (10-11-2023)Get full text
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EXTH-09. GENE MODIFICATION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS FOR IMPROVEMENT OF IMMUNOTHERAPIES FOR MALIGNANT GLIOMAS
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Patients living with high-grade gliomas have a poor survival prognosis. Furthermore, standard of care treatment for these malignant gliomas has not…”
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IMMU-50. GLIOBLASTOMA MANIPULATES HEMATOPOIETIC STEM CELL DIFFERENTIATION OUTCOMES AND DRIVES ALTERED IMMUNE RECONSTITUTION
Published in Neuro-oncology (Charlottesville, Va.) (12-11-2021)Get full text
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TMIC-55. IMMUNE DIGITAL-SPATIAL PROFILING AND CHARACTERIZATION OF GLIOMA MICROENVIRONMENT AFTER ADOPTIVE CELLULAR THERAPY
Published in Neuro-oncology (Charlottesville, Va.) (14-11-2022)Get full text
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IMMU-42. ADOPTIVE HEMATOPOIETIC STEM CELL AND APD1 THERAPY CONVERGE IN THE THYMUS TO PROMOTE ANTI-GLIOBLASTOMA IMMUNITY
Published in Neuro-oncology (Charlottesville, Va.) (14-11-2022)“…Our lab previously published that adoptive hematopoietic stem cell (HSC) therapy administered in conjunction with aPD1 increases median survival in multiple…”
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EXTH-70. IMMUNOTHERAPY REVERSES GLIOMA-DRIVEN DYSFUNCTION OF IMMUNE SYSTEM HOMEOSTASIS
Published in Neuro-oncology (Charlottesville, Va.) (14-11-2022)Get full text
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High grade gliomas impact cell fate differentiation of hematopoietic stem and progenitor cells in the bone marrow
Published in The Journal of immunology (1950) (01-05-2021)“…Glioblastoma (GBM) remains a deadly disease with an overall survival of 18 months. Despite advances in cancer immunotherapy, especially in the context of solid…”
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GLIOMA-14 ELUCIDATING THE CELL-CELL INTERACTIONS AND GEO-SPATIAL ORIENTATION OF M2 POLARIZED MACROPHAGES/MICROGLIA WITHIN GBM'S TME AND INVESTIGATING THEIR IMMUNOSUPPRESSIVE EFFECT ON DENDRITIC CELLS
Published in Neuro-oncology advances (31-10-2023)“…Glioblastoma (GBM) is an incredibly aggressive and prevalent primary CNS tumor with dismal survival outcomes. GBM’s intra-tumor heterogeneity and lack of…”
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Abstract 4611: Leveraging organotypic brain slice models to enhance adoptive cellular therapies
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Glioblastoma (GBM) is an incredibly aggressive and prevalent primary CNS tumor with dismal survival outcomes. GBM’s intra-tumor heterogeneity and lack of…”
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