Search Results - "Falcón, Silvia"
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Multicenter Phase III Comparison of Cisplatin/S-1 With Cisplatin/Infusional Fluorouracil in Advanced Gastric or Gastroesophageal Adenocarcinoma Study: The FLAGS Trial
Published in Journal of clinical oncology (20-03-2010)“…Patients with advanced gastric or gastroesophageal adenocarcinoma need more efficacious and safer treatments than established today. S-1, a contemporary oral…”
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Multinational, Double-Blind, Phase III Study of Prednisone and Either Satraplatin or Placebo in Patients With Castrate-Refractory Prostate Cancer Progressing After Prior Chemotherapy: The SPARC Trial
Published in Journal of clinical oncology (10-11-2009)“…This multinational, double-blind, randomized, placebo-controlled, phase III trial assessed the efficacy and tolerability of the oral platinum analog…”
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Adaptation of international coronavirus disease 2019 and breast cancer guidelines to local context
Published in World journal of clinical oncology (24-01-2021)“…The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (a novel coronavirus), which was first identified…”
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Practice-Changing Use of the 21-Gene Test for the Management of Patients With Early-Stage Breast Cancer in Latin America
Published in JCO global oncology (01-12-2021)“…We present a physician survey of the impact of 21-gene Breast Recurrence Score test results on treatment decisions in clinical practice in Latin America. This…”
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Treatment of Advanced Hormone-Sensitive Breast Cancer in Postmenopausal Women With Exemestane Alone or in Combination With Celecoxib
Published in Journal of clinical oncology (10-03-2008)“…Preclinical data showed that the combination of exemestane and celecoxib has synergistic effects. Therefore, a study was undertaken to explore the efficacy and…”
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Predictors of response and surgical approach after neoadjuvant chemotherapy in receptor-positive/HER2-negative stage II-III breast cancer patients treated in two private cancer care centers in Lima, Peru: Real-world data
Published in Journal of clinical oncology (01-06-2024)“…e12659 Background: The role of neoadjuvant chemotherapy (NAC) in hormone receptor-positive HER2-negative breast cancer (BC) is controversial, its main benefit…”
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Clinical Outcomes in Adult T Leukemia/Lymphoma: Report of 55 Cases from Peru
Published in Blood (16-11-2005)“…Adult T -cell leukaemia/lymphoma (ATL) is an aggressive disease associated with human T-cell lymphotropic virus type-I (HTLV-I) with heterogeneous clinical…”
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Phase II randomized trial comparing sequential first-line everolimus and second-line sunitinib versus first-line sunitinib and second-line everolimus in patients with metastatic renal cell carcinoma
Published in Journal of clinical oncology (01-09-2014)“…A multicenter, randomized phase II trial, RECORD-3, was conducted to compare first-line everolimus followed by sunitinib at progression with the standard…”
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HannaH phase III randomised study: Association of total pathological complete response with event-free survival in HER2-positive early breast cancer treated with neoadjuvant–adjuvant trastuzumab after 2 years of treatment-free follow-up
Published in European journal of cancer (1990) (01-07-2016)“…Abstract Background In the phase III, open-label, randomised HannaH study, fixed-dose neoadjuvant–adjuvant subcutaneous trastuzumab for human epidermal growth…”
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Practice-changing use of the 21-gene oncotype DX breast recurrence score test in Latin American hospitals
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e12539 Background: The 21-gene test is clinically validated to predict chemotherapy (CT) benefit in node-negative (N0) and node-positive (up to 3…”
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Neoadjuvant pertuzumab in non‑metastatic HER2‑positive breast tumors: Multicentric study in Peru (NeoHer)
Published in Molecular and clinical oncology (01-03-2022)“…Several clinical trials have demonstrated the benefit of adding pertuzumab to trastuzumab plus neoadjuvant chemotherapy in the treatment of human epidermal…”
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Clinical validation of 2 morbidity groups in the primary care setting
Published in Atención primaria (01-02-2020)“…Adjusted Morbidity Groups (GMAs) and the Clinical Risk Groups (CRGs) are population morbidity based stratification tools which classify patients into mutually…”
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Record-3: Phase II randomized trial comparing sequential first-line everolimus (EVE) and second-line sunitinib (SUN) versus first-line SUN and second-line EVE in patients with metastatic renal cell carcinoma (mRCC)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 4504 Background: Sequential SUN (tyrosine kinase inhibitor, TKI) until progression of disease (PD) followed by EVE (mTOR inhibitor) is standard…”
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Abstract PO2-05-06: Palbociclib in advanced hormone receptor positive breast cancer: A real world study in South America
Published in Cancer research (Chicago, Ill.) (02-05-2024)“…BACKGROUND: First-line combined endocrine therapy is the standard of care for hormone receptor-positive (HR+) human epidermal growth factor receptor 2…”
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Validación clínica de 2 agrupadores de morbilidad en el ámbito de atención primaria
Published in Atención primaria (01-02-2020)“…Resumen Introducción Los grupos de morbilidad ajustados (GMA) y los clinical risk groups (CRG) son herramientas de estratificación poblacional basada en la…”
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Abstract P4-06-12: Decision of Neoadjuvant Therapy in Younger vs. Older Breast Cancer Patients: A Real-World Data Analysis
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Background: The incidence of breast cancer among younger patients (age ≤ 40) is higher in Latin America than in other regions. The multidisciplinary approach…”
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A Multicenter, Single-Arm Phase II Study of Pemetrexed Plus Doxorubicin Administered Every 21 Days in Patients With Advanced Breast Cancer
Published in Clinical breast cancer (01-08-2009)“…Abstract Background Doxorubicin and pemetrexed have both shown single-agent activity in breast cancer. Preclinical and clinical evidence indicates that a…”
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A phase II study of neoadjuvant gemcitabine plus doxorubicin in stage IIIB breast cancer: a preliminary report
Published in Seminars in oncology (01-06-2001)“…The purpose of this ongoing study is to determine the response and safety of a combination of gemcitabine (Gemzar; Eli Lilly and Company, Indianapolis, IN)…”
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