Search Results - "Falcão, Manuel A"

Dynamic Ex Vivo Porcine Eye Model to Measure Ophthalmic Drug Penetration under Simulated Lacrimal Flow by Barbalho, Geisa N, Falcão, Manuel A, Lopes, Jefferson M. S, Lopes, Júlia M, Contarato, Jonad L. A, Gelfuso, Guilherme M, Cunha-Filho, Marcilio, Gratieri, Tais

“…Animal models are still used in the research and development of ophthalmic drug products, mainly due to the difficulty in simulating natural physiological…”
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Hydrogel-based hybrid membrane enhances in vitro ophthalmic drug evaluation in the OphthalMimic device by Barbalho, Geisa N., Falcão, Manuel A., Amaral, Venâncio A., Contarato, Jonad L., Gelfuso, Guilherme M., Cunha-Filho, Marcilio, Gratieri, Tais

“…•The OphtalMimic device offers a precise simulation of human ocular conditions for improved ophthalmic drug product evaluation.•A novel hydrogel-based hybrid…”
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OphthalMimic: A new alternative apparatus without animal tissue for the evaluation of topical ophthalmic drug products by Barbalho, Geisa N., Falcão, Manuel A., Alves Amaral, Venâncio, Contarato, Jonad L.A., Barbalho, Aliucha M., Kaori Diógenes, Gabriela, Mariana Gomes Silva, Melyssa, Carvalho de Barros do Vale Rochelle, Beatriz, Gelfuso, Guilherme M., Cunha-Filho, Marcilio, Gratieri, Tais

“…•Novel in vitro methods are necessary to substitute costly, slow, and highly complexin vivomodels to evaluate ophthalmic formulations.•The efficacy of topical…”
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Lipid-polymer hybrid nanoparticles as a targeted drug delivery system for melanoma treatment by Scopel, Rodrigo, Falcão, Manuel A., Cappellari, Angélica Regina, Morrone, Fernanda B., Guterres, Silvia S., Cassel, Eduardo, Kasko, Andrea M., Vargas, Rubem M. F.

“…Aiming to target vitamin D receptors (VDR) expressed in melanoma cells, vitamin D 3 functionalized hybrid lipid-polymer nanoparticles (HNP-VDs) comprising a…”
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Supercritical fluid extraction of vinblastine from Catharanthus roseus by Falcão, Manuel A., Scopel, Rodrigo, Almeida, Rafael N., do Espirito Santo, Alexandre Timm, Franceschini, Gustavo, Garcez, José Jacques, Vargas, Rubem M.F., Cassel, Eduardo

“…[Display omitted] •The CO2+ethanol (2%) presented selectivity to vinblastine extraction from C. roseus.•SFE of vinblastine is more efficient when compared to…”
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Evaluation of visual acuity, macular status, and subfoveal choroidal thickness changes after cataract surgery in eyes with diabetic retinopathy by Brito, Pedro N, Rosas, Vítor M, Coentrão, Luís M, Carneiro, Ângela V, Rocha-Sousa, Amândio, Brandão, Elisete, Falcão-Reis, Fernando, Falcão, Manuel A

“…Progression of diabetic macular edema has been reported as a common cause of poor visual acuity recovery after cataract surgery in patients with diabetes…”
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In Vitro Performance Analysis of a Minoxidil Thermosensitive Gel with Reduced Runoff for Eyebrow Hair Growth by Xavier, Luciano C G, Matos, Breno N, Barbalho, Geisa N, Falcão, Manuel A, Cunha-Filho, Marcilio, Gelfuso, Guilherme M, Gratieri, Tais

“…There is a growing interest in innovative products for eyebrow hair loss treatment with fewer adverse effects. Nevertheless, a fundamental formulation aspect…”
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Impact of gas chromatography and mass spectrometry combined with gas chromatography and olfactometry for the sex differentiation of Baccharis articulata by the analysis of volatile compounds by Minteguiaga, Manuel, Umpiérrez, Noelia, Fariña, Laura, Falcão, Manuel A., Xavier, Vanessa. B., Cassel, Eduardo, Dellacassa, Eduardo

“…The Baccharis genus has more than 400 species of aromatic plants. However, only approximately 50 species have been studied in oil composition to date. From…”
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Determination of antibacterial activity of vacuum distillation fractions of lemongrass essential oil by Falcão, Manuel A, Fianco, Ana L. B, Lucas, Aline M, Pereira, Marcos A. A, Torres, Fernando C, Vargas, Rubem M. F, Cassel, Eduardo

“…Essential oils are natural substances composed of terpenoids and phenylpropanoid molecules that have many biological activities. Because of their activity,…”
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Supercritical fluid extraction from Syzygium aromaticum buds: Phase equilibrium, mathematical modeling and antimicrobial activity by Scopel, Rodrigo, Falcão, Manuel A., Lucas, Aline M., Almeida, Rafael N., Gandolfi, Paulo H.K., Cassel, Eduardo, Vargas, Rubem M.F.

“…•Clove essential oil obtained by supercritical fluid extraction using CO2.•High-pressure phase equilibrium modeling with Peng–Robinson EoS.•Mathematical…”
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