Search Results - "Fako, E."

Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicity by Fako, Valerie E., Furgeson, Darin Y.

“…The lack of correlative and predictive models to assess acute and chronic toxicities limits the rapid pre-clinical development of new therapeutics. This…”
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Toxicity Assessments of Multisized Gold and Silver Nanoparticles in Zebrafish Embryos by Bar‐Ilan, Ofek, Albrecht, Ralph M., Fako, Valerie E., Furgeson, Darin Y.

“…The potential toxicity of nanoparticles is addressed by utilizing a putative attractive model in developmental biology and genetics: the zebrafish (Danio…”
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Mechanism of Orlistat Hydrolysis by the Thioesterase of Human Fatty Acid Synthase by Fako, Valerie E, Zhang, Jian-Ting, Liu, Jing-Yuan

“…Fatty acid synthase (FASN), the sole protein capable of de novo synthesis of free fatty acids, is overexpressed in a wide variety of human cancers and is…”
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Repositioning Proton Pump Inhibitors as Anticancer Drugs by Targeting the Thioesterase Domain of Human Fatty Acid Synthase by Fako, Valerie E, Wu, Xi, Pflug, Beth, Liu, Jing-Yuan, Zhang, Jian-Ting

“…Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of free fatty acids, is up-regulated in many cancers. FASN is essential for cancer…”
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Abstract 3978: Mechanism of orlistat hydrolysis by fatty acid synthase thioesterase by Fako, Valerie E., Liu, Jingyuan, Zhang, Jian-Ting

“…Abstract Fatty acid synthase (FASN), a seven domain enzyme, is the sole protein capable of de novo synthesis of free fatty acids, most commonly 16-carbon…”
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Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicity: Identifying and Assessing Biomaterial Nanotoxicity in Translational Research for Preclinical Drug Development by FAKO, Valerie E, FURGESON, Darin Y

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