Search Results - "Fakiruddin, Kamal Shaik"

Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour by Fakiruddin, Kamal Shaik, Ghazalli, Nadiah, Lim, Moon Nian, Zakaria, Zubaidah, Abdullah, Syahril

“…Tapping into the ability of engineered mesenchymal stem cells (MSCs) to mobilise into the tumour has expanded the scope of cancer treatment. Engineered MSCs…”
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Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer by Shaik Fakiruddin, Kamal, Lim, Moon Nian, Nordin, Norshariza, Rosli, Rozita, Zakaria, Zubaidah, Abdullah, Syahril

“…Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target a specific cancer stem cell…”
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Systematic review and meta-analysis of mesenchymal stromal/stem cells as strategical means for the treatment of COVID-19 by Taufiq, Hannah, Shaik Fakiruddin, Kamal, Muzaffar, Umaiya, Lim, Moon Nian, Rusli, Syahnaz, Kamaluddin, Nor Rizan, Esa, Ezalia, Abdullah, Syahril

“…Background: In coronavirus disease 2019 (COVID-19) patients, elevated levels of inflammatory cytokines from over stimulation of immune cells have become a…”
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Chemo-Sensitization of CD133+ Cancer Stem Cell Enhances the Effect of Mesenchymal Stem Cell Expressing TRAIL in Non-Small Cell Lung Cancer Cell Lines by Fakiruddin, Kamal Shaik, Lim, Moon Nian, Nordin, Norshariza, Rosli, Rozita, Abdullah, Syahril

“…Pre-clinical studies have demonstrated the efficacy of mesenchymal stem cells (MSCs) expressing tumor necrosis factor (TNF)-related apoptosis-inducing ligand…”
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A comparative study of non-viral gene delivery techniques to human adipose-derived mesenchymal stem cell by Abdul Halim, Nur Shuhaidatul Sarmiza, Fakiruddin, Kamal Shaik, Ali, Syed Atif, Yahaya, Badrul Hisham

“…Mesenchymal stem cells (MSCs) hold tremendous potential for therapeutic use in stem cell-based gene therapy. Ex vivo genetic modification of MSCs with…”
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The Effects of Lentivirus-Mediated Gene Silencing of RARβ on the Stemness Capability of Non-Small Cell Lung Cancer by Abu Halim, Noor Hanis, Zakaria, Norashikin, Theva Das, Kumitaa, Lin, Juntang, Lim, Moon Nian, Fakiruddin, Kamal Shaik, Yahaya, Badrul Hisham

“…Retinoic acid receptor beta is a nuclear receptor protein that binds to retinoic acid (RA) to mediate cellular signalling in embryogenic morphogenesis, cell…”
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Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton's jelly mesenchymal stromal cells by Rengasamy, Mathiyazhagan, Singh, Gurbind, Fakharuzi, Noor Atiqah, Siddikuzzaman, Balasubramanian, Sudha, Swamynathan, Priyanka, Thej, Charan, Sasidharan, Gopinath, Gupta, Pawan Kumar, Das, Anjan Kumar, Rahman, Ahmad Zuhairi Abd, Fakiruddin, Kamal Shaik, Nian, Lim Moon, Zakaria, Zubaidah, Majumdar, Anish S

“…Mesenchymal stromal cells (MSCs) from various tissues have shown moderate therapeutic efficacy in reversing liver fibrosis in preclinical models. Here, we…”
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CRISPR/Cas9 in Stem Cell Research: Current Application and Future Perspective by Patmanathan, Sathya Narayanan, Gnanasegaran, Nareshwaran, Lim, Moon Nian, Husaini, Roslina, Fakiruddin, Kamal Shaik, Zakaria, Zubaidah

“…The clustered regularly interspaced short palindromic repeats-associated protein 9 or CRISPR/Cas9 system is one of the hottest topics discussed lately due to…”
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Curcumin improves the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines by BAHARUDDIN, PUTERI, SATAR, NAZILAH, FAKIRUDDIN, KAMAL SHAIK, ZAKARIA, NORASHIKIN, LIM, MOON NIAN, YUSOFF, NARAZAH MOHD, ZAKARIA, ZUBAIDAH, YAHAYA, BADRUL HISHAM

“…Natural compounds such as curcumin have the ability to enhance the therapeutic effectiveness of common chemotherapy agents through cancer stem-like cell (CSC)…”
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Human non-small cell lung cancer expresses putative cancer stem cell markers and exhibits the transcriptomic profile of multipotent cells by Zakaria, Norashikin, Yusoff, Narazah Mohd, Zakaria, Zubaidah, Lim, Moon Nian, Baharuddin, Puteri J Noor, Fakiruddin, Kamal Shaik, Yahaya, Badrul

“…Despite significant advances in staging and therapies, lung cancer remains a major cause of cancer-related lethality due to its high incidence and recurrence…”
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Engineered Mesenchymal Stem Cells as Treatment for Cancers: Opportunities, Clinical Applications and Challenges by Shamsul Kamal, Aishah Amirah, Fakiruddin, Kamal Shaik, Bobbo, Khadijat Abubakar, Ling, King Hwa, Vidyadaran, Sharmili, Abdullah, Syahril

“…The insufficient and unspecific target of classical chemotherapies often leads to therapy resistance and cancer recurrence. Over the past decades, discoveries…”
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Novel triple‑positive markers identified in human non‑small cell lung cancer cell line with chemotherapy-resistant and putative cancer stem cell characteristics by Satar, Nazilah Abdul, Fakiruddin, Kamal Shaik, Lim, Moon Nian, Mok, Pooi Ling, Zakaria, Norashikin, Fakharuzi, Noor Atiqah, Abd Rahman, Ahmad Zuhairi, Zakaria, Zubaidah, Yahaya, Badrul Hisham, Baharuddin, Puteri

“…Through the specific identification and direct targeting of cancer stem cells (CSCs), it is believed that a better treatment efficacy of cancer may be…”
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Nucleofection optimization and in vitro anti-tumourigenic effect of TRAIL-expressing human adipose-derived mesenchymal stromal cells by Fakiruddin, Kamal Shaik, Baharuddin, Puteri, Lim, Moon Nian, Fakharuzi, Noor Atiqah, Yusof, Nurul Ain Nasim M, Zakaria, Zubaidah

“…Tumour homing capacity of engineered human adipose-derived mesenchymal stromal cells (ADMSCs) expressing anti-tumour agents might be the key for a much safer…”
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Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study by Bong, Ivyna Pau Ni, Ng, Ching Ching, Fakiruddin, Shaik Kamal, Lim, Moon Nian, Zakaria, Zubaidah

“…Multiple myeloma (MM) is a malignancy of B lymphocytes or plasma cells. Our array-based comparative genomic hybridization findings revealed chromosomal gains…”
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Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase induce growth inhibition and apoptosis in human multiple myeloma cells: a preliminary study by Bong, Ivyna Pau Ni, Ng, Ching Ching, Fakiruddin, Shaik Kamal, Lim, Moon Nian, Zakaria, Zubaidah

“…Multiple myeloma (MM) is a malignancy of B lymphocytes or plasma cells. Our array-based comparative genomic hybridization findings revealed chromosomal gains…”
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